Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10265375 . A C CCDS13109.1:NM_003081.3:c.118Aaa>Caa_NP_003072.2:p.40K>Q Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 LYS G:43 H:40 46.0 0.23 H -76.3 -32.2 12.0 0.06 0.17 J:P54921:0.17
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 LYS G:43 H:40 43.0 0.215 H -69.8 -36.6 18.0 0.09 0.125 J:P54921:0.125
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 LYS G:43 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 LYS G:43 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 LYS M:34 M:40 37.0 0.185 H -70.9 -44.2 3.0 0.015 0.17 J:P54921:0.17
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 LYS M:24 M:40 53.0 0.265 H -66.0 -35.7 2.0 0.01 0.255 L:P32851:0.01
J:P54921:0.24
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 LYS M:24 M:40 51.0 0.255 H -66.6 -44.8 9.0 0.045 0.21 J:P54921:0.21
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 LYS M:24 M:40 51.0 0.255 H -66.5 -44.9 10.0 0.05 0.205 J:P54921:0.205
6ip1 3 P60881 91.0 1e-59 EM
 2019-04-24 LYS C:42 C:40 140.0 0.7 H -76.9 -41.9 22.0 0.11 0.59 D:P60881:0.415
F:A5D7S0:0.235
1sfc 3 P60881 100.0 3e-51 X-RAY
 1998-10-28 LYS C:40 C:40 132.0 0.66 H -62.7 -38.0 60.0 0.3 0.36 B:P32851:0.005
D:P60881:0.36
 SR
SR
HOH
 8.468
5.097
6.872
 NZ
NZ
NZ
 SR
SR
O
LYS G:40 G:40 137.0 0.685 H -49.8 -53.2 NA NA NA
LYS K:40 K:40 138.0 0.69 H -60.7 -37.5 NA NA NA
1urq 3 P13795 97.47 4e-47 X-RAY
 2004-08-26 LYS C:37 C:40 104.0 NA H -62.0 -43.7 44.0 NA NA D:P13795:NA
 HOH
 3.447
 CE
 O
3hd7 3 P60881 97.47 4e-47 X-RAY
 2009-07-14 LYS C:37 C:40 137.0 0.685 H -76.6 -46.1 67.0 0.335 0.35 B:P32851:0.005
D:P60881:0.35
 SO4
 8.424
 C
 O3
LYS G:37 G:40 137.0 0.685 H -69.0 -47.5 NA NA NA
3ipd 3 P60881 97.47 4e-47 X-RAY
 2009-09-01 LYS C:37 C:40 139.0 0.695 H -72.6 -56.0 78.0 0.39 0.305 D:P60881:0.305
LYS G:37 G:40 138.0 0.69 H -73.0 -55.6 NA NA NA
1n7s 3 P60881 100.0 5e-47 X-RAY
 2002-12-27 LYS C:36 C:40 114.0 0.57 H -65.3 -41.9 49.0 0.245 0.325 B:P32851:0.01
D:P60881:0.325
 HOH
 2.617
 NZ
 O
2n1t 3 P60880 100.0 5e-47 NMR
 2015-06-03 LYS C:34 C:40 149.0 0.745 H -63.1 -43.5 77.0 0.385 0.36 D:P60880:0.36
5ccg 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LYS C:34 C:40 113.0 0.565 H -60.7 -54.5 0.0 0.0 0.565 D:P60881:0.315
E:P21707:0.335
 CA
HOH
 8.322
7.805
 NZ
NZ
 CA
O
LYS I:34 I:40 126.0 0.63 H -60.5 -52.9 NA NA NA
5cch 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LYS C:34 C:40 123.0 0.615 H -64.9 -43.2 3.0 0.015 0.6 D:P60881:0.335
E:P21707:0.385
5cci 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LYS C:34 C:40 124.0 0.62 H -52.9 -56.5 3.0 0.015 0.605 D:P60881:0.395
E:P21707:0.335
5w5c 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 LYS C:34 C:40 124.0 0.62 H -62.1 -41.2 54.0 0.27 0.35 B:P32851:0.005
D:P60881:0.35
 HOH
 2.589
 NZ
 O
5w5d 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 LYS C:34 C:40 125.0 0.625 H -60.7 -44.1 59.0 0.295 0.33 D:P60881:0.33
 HOH
 6.494
 O
 O
6mti 5 P60881 100.0 5e-47 EM
 2019-04-24 LYS I:34 C:40 126.0 0.63 H -53.0 -56.5 3.0 0.015 0.615 J:P60881:0.4
C:P21707:0.31
LYS M:34 G:40 127.0 0.635 H -53.0 -56.4 9.0 0.045 0.59 B:P21707:0.305
N:P60881:0.41
LYS Q:34 K:40 125.0 0.625 H -53.1 -56.4 46.0 0.23 0.395 P:P32851:0.005
R:P60881:0.395
LYS U:34 O:40 127.0 0.635 H -53.0 -56.5 14.0 0.07 0.565 V:P60881:0.405
D:P21707:0.265
LYS Y:34 S:40 127.0 0.635 H -53.0 -56.4 1.0 0.005 0.63 E:P21707:0.335
Z:P60881:0.4
LYS CA:34 W:40 125.0 0.625 H -52.9 -56.5 45.0 0.225 0.4 DA:P60881:0.4
5low 2 P60881 100.0 3e-46 X-RAY
 2017-06-21 LYS D:53 D:40 138.0 0.69 H -63.6 -49.6 35.0 0.175 0.515 A:P47709:0.19
E:P60881:0.325
 HOH
 6.065
 C
 O
LYS F:53 F:40 145.0 0.725 H -69.6 -36.2 47.0 0.235 0.49 G:P60881:0.41
B:P47709:0.075
 HOH
 8.114
 CE
 O
LYS K:53 K:40 148.0 0.74 H -69.6 -44.8 NA NA NA
LYS M:53 M:40 152.0 0.76 H -67.3 -44.7 NA NA NA
5lob 2 P60881 100.0 4e-46 X-RAY
 2017-06-21 LYS D:58 D:40 148.0 0.74 H -70.0 -38.4 34.0 0.17 0.57 A:P47709:0.14
E:P60881:0.435
 SO4
 5.500
 CE
 O3
LYS F:58 F:40 140.0 0.7 H -68.8 -47.3 40.0 0.2 0.5 G:P60881:0.42
B:P47709:0.08
1jth 1 P60881 92.68 4e-46 X-RAY
 2001-11-28 LYS A:40 A:40 133.0 0.665 H -66.3 -38.1 50.0 0.25 0.415 B:P32851:0.415
 HOH
 5.721
 NZ
 O
LYS C:40 C:40 143.0 0.715 H -59.9 -48.1 65.0 0.325 0.39 B:P32851:0.02
D:P32851:0.39
 HOH
 5.952
 CE
 O
3rk2 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LYS C:38 C:40 137.0 0.685 H -61.4 -51.1 64.0 0.32 0.365 D:P60880:0.365
B:P32851:0.005
 HOH
 6.914
 O
 O
LYS G:38 G:40 137.0 0.685 H -54.9 -52.8 NA NA NA
3rk3 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LYS C:38 C:40 140.0 0.7 H -66.1 -53.8 55.0 0.275 0.425 D:P60880:0.425
3rl0 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LYS C:38 C:40 130.0 0.65 H -64.8 -47.1 56.0 0.28 0.37 D:P60880:0.37
LYS G:38 G:40 127.0 0.635 H -65.7 -46.2 NA NA NA
LYS K:38 K:40 131.0 0.655 H -63.7 -46.5 NA NA NA
LYS O:38 O:40 133.0 0.665 H -64.4 -46.7 NA NA NA
LYS S:38 S:40 129.0 0.645 H -65.3 -46.7 NA NA NA
LYS W:38 W:40 131.0 0.655 H -64.6 -47.6 NA NA NA
LYS AA:38 a:40 128.0 0.64 H -64.8 -47.5 NA NA NA
LYS EA:38 e:40 129.0 0.645 H -63.2 -46.9 NA NA NA
5kj7 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 LYS C:32 C:40 113.0 0.565 H -61.6 -51.4 0.0 0.0 0.565 B:P32851:0.005
E:P21707:0.34
D:P60881:0.325
 CA
HOH
 7.903
7.579
 NZ
NZ
 CA
O
LYS I:32 I:40 125.0 0.625 H -61.9 -49.6 NA NA NA
5kj8 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 LYS C:32 C:40 114.0 0.57 H -63.4 -52.3 0.0 0.0 0.57 D:P60881:0.325
E:P21707:0.355
LYS I:32 I:40 120.0 0.6 H -63.4 -52.9 NA NA NA
6wvw 3 P60881 98.65 1e-43 X-RAY
 2021-03-17 LYS C:31 C:40 123.0 0.615 H -64.7 -45.0 56.0 0.28 0.335 D:P60881:0.335
 HOH
 5.124
 O
 O
LYS G:31 G:40 135.0 0.675 H -65.4 -42.9 NA NA NA
1kil 3 P60880 100.0 3e-42 X-RAY
 2002-03-13 LYS C:32 C:40 134.0 0.67 H -59.5 -50.0 65.0 0.325 0.345 D:P60880:0.345
B:P32851:0.005
 HOH
 7.021
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 LYS A:40 A:40 57.0 0.285 H -62.5 -46.7