Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10265384 . G A CCDS13109.1:NM_003081.3:c.127Ggt>Agt_NP_003072.2:p.43G>S Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 GLY G:46 H:43 22.0 0.293 H -72.7 -52.6 9.0 0.12 0.173 H:P32851:0.173
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 GLY G:46 H:43 18.0 0.24 H -72.7 -49.2 6.0 0.08 0.16 H:P32851:0.16
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 GLY G:46 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 GLY G:46 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 GLY M:37 M:43 10.0 0.133 H -78.5 -31.5 7.0 0.093 0.04 L:P32851:0.04
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 GLY M:27 M:43 10.0 0.133 H -67.5 -40.1 1.0 0.013 0.12 L:P32851:0.12
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 GLY M:27 M:43 8.0 0.107 H -78.0 -35.3 4.0 0.053 0.054 L:P32851:0.053
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 GLY M:27 M:43 9.0 0.12 H -77.9 -35.4 4.0 0.053 0.067 L:P32851:0.067
6ip1 3 P60881 91.0 1e-59 EM
 2019-04-24 GLY C:45 C:43 38.0 0.507 H -68.6 -34.3 2.0 0.027 0.48 D:P60881:0.333
B:P32851:0.213
1sfc 3 P60881 100.0 3e-51 X-RAY
 1998-10-28 GLY C:43 C:43 32.0 0.427 H -66.9 -50.7 0.0 0.0 0.427 B:P32851:0.267
D:P60881:0.307
GLY G:43 G:43 32.0 0.427 H -56.9 -59.4 NA NA NA
GLY K:43 K:43 30.0 0.4 H -72.4 -40.4 NA NA NA
1urq 3 P13795 97.47 4e-47 X-RAY
 2004-08-26 GLY C:40 C:43 32.0 0.427 H -62.3 -42.4 0.0 0.0 0.427 B:P32851:0.24
D:P13795:0.333
 HOH
 3.773
 CA
 O
3hd7 3 P60881 97.47 4e-47 X-RAY
 2009-07-14 GLY C:40 C:43 28.0 0.373 H -73.2 -45.2 0.0 0.0 0.373 B:P32851:0.253
D:P60881:0.267
 SO4
 8.853
 N
 O2
GLY G:40 G:43 26.0 0.347 H -70.4 -44.1 NA NA NA
3ipd 3 P60881 97.47 4e-47 X-RAY
 2009-09-01 GLY C:40 C:43 22.0 0.293 H -98.7 -44.3 0.0 0.0 0.293 B:P32851:0.24
D:P60881:0.2
GLY G:40 G:43 21.0 0.28 H -99.7 -44.1 NA NA NA
1n7s 3 P60881 100.0 5e-47 X-RAY
 2002-12-27 GLY C:39 C:43 33.0 0.44 H -63.1 -40.0 0.0 0.0 0.44 B:P32851:0.267
D:P60881:0.347
 HOH
 3.670
 CA
 O
2n1t 3 P60880 100.0 5e-47 NMR
 2015-06-03 GLY C:37 C:43 37.0 0.493 H -53.4 -51.7 0.0 0.0 0.493 B:P32851:0.253
D:P60880:0.32
5ccg 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 GLY C:37 C:43 31.0 0.413 H -63.9 -45.1 0.0 0.0 0.413 B:P32851:0.28
D:P60881:0.28
GLY I:37 I:43 29.0 0.387 H -63.5 -44.7 NA NA NA
5cch 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 GLY C:37 C:43 33.0 0.44 H -60.1 -41.6 0.0 0.0 0.44 B:P32851:0.28
D:P60881:0.307
5cci 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 GLY C:37 C:43 32.0 0.427 H -60.8 -45.8 0.0 0.0 0.427 B:P32851:0.267
D:P60881:0.307
5w5c 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 GLY C:37 C:43 34.0 0.453 H -64.5 -38.3 0.0 0.0 0.453 B:P32851:0.28
D:P60881:0.36
 HOH
 3.540
 CA
 O
5w5d 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 GLY C:37 C:43 34.0 0.453 H -66.3 -40.8 0.0 0.0 0.453 D:P60881:0.347
B:P32851:0.28
 HOH
 3.605
 CA
 O
6mti 5 P60881 100.0 5e-47 EM
 2019-04-24 GLY I:37 C:43 33.0 0.44 H -60.8 -45.8 0.0 0.0 0.44 J:P60881:0.293
H:P32851:0.28
GLY M:37 G:43 32.0 0.427 H -60.8 -45.8 0.0 0.0 0.427 N:P60881:0.307
L:P32851:0.267
GLY Q:37 K:43 33.0 0.44 H -60.9 -45.8 0.0 0.0 0.44 P:P32851:0.267
R:P60881:0.32
GLY U:37 O:43 32.0 0.427 H -60.7 -45.9 0.0 0.0 0.427 V:P60881:0.307
T:P32851:0.253
GLY Y:37 S:43 32.0 0.427 H -60.8 -45.8 0.0 0.0 0.427 X:P32851:0.28
Z:P60881:0.293
GLY CA:37 W:43 32.0 0.427 H -60.8 -45.8 0.0 0.0 0.427 BA:P32851:0.28
DA:P60881:0.293
5low 2 P60881 100.0 3e-46 X-RAY
 2017-06-21 GLY D:56 D:43 27.0 0.36 H -66.9 -27.3 0.0 0.0 0.36 F:P60881:0.213
E:P60881:0.24
 HOH
 6.026
 N
 O
GLY F:56 F:43 32.0 0.427 H -63.7 -43.3 0.0 0.0 0.427 D:P60881:0.213
G:P60881:0.32
GLY K:56 K:43 35.0 0.467 H -65.3 -33.4 NA NA NA
GLY M:56 M:43 33.0 0.44 H -68.6 -42.3 NA NA NA
5lob 2 P60881 100.0 4e-46 X-RAY
 2017-06-21 GLY D:61 D:43 32.0 0.427 H -74.0 -28.5 0.0 0.0 0.427 F:P60881:0.28
E:P60881:0.213
 SO4
 8.336
 O
 O2
GLY F:61 F:43 34.0 0.453 H -68.7 -30.6 0.0 0.0 0.453 G:P60881:0.28
D:P60881:0.227
1jth 1 P60881 92.68 4e-46 X-RAY
 2001-11-28 GLY A:43 A:43 30.0 0.4 H -57.4 -46.3 0.0 0.0 0.4 B:P32851:0.293
D:P32851:0.307
 HOH
 7.518
 O
 O
GLY C:43 C:43 33.0 0.44 H -63.5 -34.8 0.0 0.0 0.44 B:P32851:0.333
D:P32851:0.293
 HOH
 6.363
 N
 O
3rk2 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 GLY C:41 C:43 33.0 0.44 H -55.8 -49.8 0.0 0.0 0.44 D:P60880:0.28
B:P32851:0.293
A:P63027:0.027
 HOH
 3.781
 CA
 O
GLY G:41 G:43 34.0 0.453 H -68.3 -37.0 NA NA NA
3rk3 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 GLY C:41 C:43 30.0 0.4 H -57.1 -47.8 0.0 0.0 0.4 B:P32851:0.24
D:P60880:0.253
3rl0 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 GLY C:41 C:43 33.0 0.44 H -58.8 -55.8 0.0 0.0 0.44 D:P60880:0.293
B:P32851:0.24
GLY G:41 G:43 32.0 0.427 H -58.9 -55.8 NA NA NA
GLY K:41 K:43 33.0 0.44 H -57.8 -56.1 NA NA NA
GLY O:41 O:43 32.0 0.427 H -57.6 -55.5 NA NA NA
GLY S:41 S:43 31.0 0.413 H -58.8 -55.8 NA NA NA
GLY W:41 W:43 32.0 0.427 H -59.1 -55.5 NA NA NA
GLY AA:41 a:43 32.0 0.427 H -57.0 -56.1 NA NA NA
GLY EA:41 e:43 32.0 0.427 H -58.3 -55.6 NA NA NA
5kj7 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 GLY C:35 C:43 32.0 0.427 H -65.5 -43.8 0.0 0.0 0.427 B:P32851:0.28
D:P60881:0.28
GLY I:35 I:43 30.0 0.4 H -65.0 -43.9 NA NA NA
5kj8 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 GLY C:35 C:43 32.0 0.427 H -66.2 -39.0 0.0 0.0 0.427 D:P60881:0.307
B:P32851:0.293
GLY I:35 I:43 30.0 0.4 H -66.0 -38.8 NA NA NA
6wvw 3 P60881 98.65 1e-43 X-RAY
 2021-03-17 GLY C:34 C:43 32.0 0.427 H -65.3 -40.1 0.0 0.0 0.427 D:P60881:0.347
B:P32851:0.267
 HOH
 2.624
 HA2
 O
GLY G:34 G:43 32.0 0.427 H -64.3 -38.6 NA NA NA
1kil 3 P60880 100.0 3e-42 X-RAY
 2002-03-13 GLY C:35 C:43 31.0 0.413 H -63.2 -49.7 0.0 0.0 0.413 D:P60880:0.267
B:P32851:0.267
 HOH
 3.972
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 GLY A:43 A:43 9.0 0.12 H -59.5 -45.1