Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10265399 . G A CCDS13109.1:NM_003081.3:c.142Gtt>Att_NP_003072.2:p.48V>I Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 VAL G:51 H:48 82.0 0.529 H -66.3 -49.4 35.0 0.226 0.303 J:P54921:0.303
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 VAL G:51 H:48 82.0 0.529 H -67.4 -52.4 47.0 0.303 0.226 J:P54921:0.226
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 VAL G:51 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 VAL G:51 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 VAL M:42 M:48 98.0 0.632 H -71.4 -27.9 40.0 0.258 0.374 J:P54921:0.374
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 VAL M:32 M:48 88.0 0.568 H -60.8 -37.2 38.0 0.245 0.323 J:P54921:0.323
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 VAL M:32 M:48 85.0 0.548 H -49.1 -38.6 35.0 0.226 0.322 J:P54921:0.323
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 VAL M:32 M:48 85.0 0.548 H -49.0 -38.6 38.0 0.245 0.303 J:P54921:0.303
6ip1 3 P60881 91.0 1e-59 EM
 2019-04-24 VAL C:50 C:48 94.0 0.606 H -69.4 -39.5 45.0 0.29 0.316 F:A5D7S0:0.316
1sfc 3 P60881 100.0 3e-51 X-RAY
 1998-10-28 VAL C:48 C:48 72.0 0.465 H -48.7 -56.8 72.0 0.465 0.0
VAL G:48 G:48 96.0 0.619 H -72.3 -47.0 NA NA NA
VAL K:48 K:48 89.0 0.574 H -70.4 -36.9 NA NA NA
1urq 3 P13795 97.47 4e-47 X-RAY
 2004-08-26 VAL C:45 C:48 73.0 0.471 H -65.1 -45.5 73.0 0.471 0.0 HOH
 2.908
 O
 O
3hd7 3 P60881 97.47 4e-47 X-RAY
 2009-07-14 VAL C:45 C:48 68.0 0.439 H -68.9 -42.7 68.0 0.439 0.0
VAL G:45 G:48 70.0 0.452 H -63.8 -36.0 NA NA NA
3ipd 3 P60881 97.47 4e-47 X-RAY
 2009-09-01 VAL C:45 C:48 80.0 0.516 H -57.2 -28.5 80.0 0.516 0.0
VAL G:45 G:48 78.0 0.503 H -57.3 -28.5 NA NA NA
1n7s 3 P60881 100.0 5e-47 X-RAY
 2002-12-27 VAL C:44 C:48 96.0 0.619 H -62.0 -44.0 96.0 0.619 0.0 HOH
 2.707
 O
 O
2n1t 3 P60880 100.0 5e-47 NMR
 2015-06-03 VAL C:42 C:48 89.0 0.574 H -64.2 -41.2 66.0 0.426 0.148 E:P21579:0.148
5ccg 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 VAL C:42 C:48 89.0 0.574 H -62.8 -45.0 15.0 0.097 0.477 E:P21707:0.477
VAL I:42 I:48 88.0 0.568 H -62.9 -45.7 NA NA NA
5cch 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 VAL C:42 C:48 93.0 0.6 H -60.0 -51.6 26.0 0.168 0.432 E:P21707:0.432
5cci 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 VAL C:42 C:48 89.0 0.574 H -57.5 -50.0 22.0 0.142 0.432 E:P21707:0.432
5w5c 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 VAL C:42 C:48 92.0 0.594 H -68.4 -41.7 92.0 0.594 0.0 HOH
 3.637
 CB
 O
5w5d 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 VAL C:42 C:48 91.0 0.587 H -57.6 -46.2 91.0 0.587 0.0 HOH
 3.787
 CB
 O
6mti 5 P60881 100.0 5e-47 EM
 2019-04-24 VAL I:42 C:48 88.0 0.568 H -57.4 -50.0 28.0 0.181 0.387 C:P21707:0.387
VAL M:42 G:48 90.0 0.581 H -57.4 -50.0 28.0 0.181 0.4 B:P21707:0.4
VAL Q:42 K:48 87.0 0.561 H -57.4 -50.0 87.0 0.561 0.0
VAL U:42 O:48 90.0 0.581 H -57.5 -50.0 34.0 0.219 0.362 D:P21707:0.361
VAL Y:42 S:48 87.0 0.561 H -57.5 -50.0 27.0 0.174 0.387 E:P21707:0.387
VAL CA:42 W:48 89.0 0.574 H -57.5 -49.9 89.0 0.574 0.0
5low 2 P60881 100.0 3e-46 X-RAY
 2017-06-21 VAL D:61 D:48 75.0 0.484 H -66.5 -49.1 8.0 0.052 0.432 A:P47709:0.432
VAL F:61 F:48 80.0 0.516 H -51.5 -44.4 5.0 0.032 0.484 B:P47709:0.484
 HOH
 7.535
 O
 O
VAL K:61 K:48 78.0 0.503 H -71.2 -48.8 NA NA NA
VAL M:61 M:48 90.0 0.581 H -65.6 -48.4 NA NA NA
5lob 2 P60881 100.0 4e-46 X-RAY
 2017-06-21 VAL D:66 D:48 63.0 0.406 H -70.2 -61.2 3.0 0.019 0.387 A:P47709:0.387
 SO4
 8.800
 O
 O4
VAL F:66 F:48 79.0 0.51 H -67.0 -22.5 6.0 0.039 0.471 B:P47709:0.471
 SO4
 8.514
 O
 O2
1jth 1 P60881 92.68 4e-46 X-RAY
 2001-11-28 VAL A:48 A:48 70.0 0.452 H -64.6 -41.0 70.0 0.452 0.0 HOH
 3.741
 CB
 O
VAL C:48 C:48 92.0 0.594 H -56.9 -51.3 92.0 0.594 0.0 HOH
 6.283
 O
 O
3rk2 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 VAL C:46 C:48 91.0 0.587 H -72.5 -49.0 91.0 0.587 0.0 CA
HOH
 9.119
7.838
 O
O
 CA
O
VAL G:46 G:48 91.0 0.587 H -76.6 -44.9 NA NA NA
3rk3 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 VAL C:46 C:48 79.0 0.51 H -46.5 -54.9 79.0 0.51 0.0
3rl0 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 VAL C:46 C:48 81.0 0.523 H -63.5 -45.0 81.0 0.523 0.0
VAL G:46 G:48 83.0 0.535 H -64.2 -45.2 NA NA NA
VAL K:46 K:48 85.0 0.548 H -64.1 -44.9 NA NA NA
VAL O:46 O:48 84.0 0.542 H -63.6 -45.4 NA NA NA
VAL S:46 S:48 84.0 0.542 H -64.2 -45.4 NA NA NA
VAL W:46 W:48 83.0 0.535 H -63.3 -45.0 NA NA NA
VAL AA:46 a:48 84.0 0.542 H -63.5 -45.8 NA NA NA
VAL EA:46 e:48 85.0 0.548 H -64.4 -44.6 NA NA NA
5kj7 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 VAL C:40 C:48 91.0 0.587 H -63.8 -44.2 15.0 0.097 0.49 E:P21707:0.49
VAL I:40 I:48 89.0 0.574 H -63.8 -44.5 NA NA NA
5kj8 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 VAL C:40 C:48 92.0 0.594 H -62.2 -49.4 13.0 0.084 0.51 E:P21707:0.51
VAL I:40 I:48 87.0 0.561 H -63.2 -50.0 NA NA NA
6wvw 3 P60881 98.65 1e-43 X-RAY
 2021-03-17 VAL C:39 C:48 70.0 0.452 H -62.1 -48.4 70.0 0.452 0.0 HOH
 2.310
 HG22
 O
VAL G:39 G:48 75.0 0.484 H -63.2 -48.0 NA NA NA
1kil 3 P60880 100.0 3e-42 X-RAY
 2002-03-13 VAL C:40 C:48 69.0 0.445 H -68.0 -46.5 69.0 0.445 0.0 MG
HOH
 9.984
4.201
 O
CB
 MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 VAL A:48 A:48 89.0 0.574 H -61.8 -42.6