Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10265406 . T A CCDS13109.1:NM_003081.3:c.149tTg>tAg_NP_003072.2:p.50L>* Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 LEU G:53 H:50 22.0 0.129 H -60.6 -37.1 10.0 0.059 0.07 H:P32851:0.071
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 LEU G:53 H:50 27.0 0.159 H -71.1 -34.0 12.0 0.071 0.088 H:P32851:0.088
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 LEU G:53 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 LEU G:53 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 LEU M:44 M:50 40.0 0.235 H -74.0 -13.8 12.0 0.071 0.164 L:P32851:0.053
K:P63045:0.129
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 LEU M:34 M:50 18.0 0.106 H -58.6 -33.5 7.0 0.041 0.065 L:P32851:0.029
K:P63045:0.035
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 LEU M:34 M:50 30.0 0.176 H -51.7 -31.8 9.0 0.053 0.123 L:P32851:0.029
K:P63045:0.094
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 LEU M:34 M:50 30.0 0.176 H -51.7 -31.8 8.0 0.047 0.129 L:P32851:0.035
K:P63045:0.094
6ip1 3 P60881 91.0 1e-59 EM
 2019-04-24 LEU C:52 C:50 97.0 0.571 H -69.4 -40.5 0.0 0.0 0.571 D:P60881:0.465
B:P32851:0.141
A:P63045:0.124
1sfc 3 P60881 100.0 3e-51 X-RAY
 1998-10-28 LEU C:50 C:50 106.0 0.624 H -63.4 -31.8 0.0 0.0 0.624 B:P32851:0.147
D:P60881:0.518
A:P63045:0.176
 SR
HOH
 6.932
7.493
 O
O
 SR
O
LEU G:50 G:50 94.0 0.553 H -53.1 -44.9 NA NA NA
LEU K:50 K:50 96.0 0.565 H -52.3 -51.7 NA NA NA
1urq 3 P13795 97.47 4e-47 X-RAY
 2004-08-26 LEU C:47 C:50 98.0 0.576 H -64.3 -35.7 1.0 0.006 0.57 B:P32851:0.106
D:P13795:0.459
A:Q9Z152:0.165
 HOH
 4.106
 CB
 O
3hd7 3 P60881 97.47 4e-47 X-RAY
 2009-07-14 LEU C:47 C:50 107.0 0.629 H -55.7 -23.7 2.0 0.012 0.617 B:P32851:0.106
D:P60881:0.506
A:P63045:0.147
LEU G:47 G:50 100.0 0.588 H -55.1 -31.8 NA NA NA
3ipd 3 P60881 97.47 4e-47 X-RAY
 2009-09-01 LEU C:47 C:50 105.0 0.618 H -57.8 -20.7 8.0 0.047 0.571 B:P32851:0.082
A:P63045:0.053
D:P60881:0.459
LEU G:47 G:50 107.0 0.629 H -58.5 -20.3 NA NA NA
1n7s 3 P60881 100.0 5e-47 X-RAY
 2002-12-27 LEU C:46 C:50 98.0 0.576 H -63.0 -35.5 1.0 0.006 0.57 A:P63045:0.153
B:P32851:0.1
D:P60881:0.459
 HOH
 4.213
 O
 O
2n1t 3 P60880 100.0 5e-47 NMR
 2015-06-03 LEU C:44 C:50 115.0 0.676 H -61.0 -44.5 12.0 0.071 0.605 A:P63045:0.076
B:P32851:0.029
D:P60880:0.582
5ccg 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LEU C:44 C:50 97.0 0.571 H -61.2 -35.8 2.0 0.012 0.559 B:P32851:0.106
D:P60881:0.453
A:P63045:0.094
 CA
 6.720
 O
 CA
LEU I:44 I:50 100.0 0.588 H -62.4 -35.1 NA NA NA
5cch 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LEU C:44 C:50 101.0 0.594 H -63.1 -37.9 0.0 0.0 0.594 B:P32851:0.1
D:P60881:0.482
A:P63045:0.141
5cci 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 LEU C:44 C:50 104.0 0.612 H -63.2 -39.5 0.0 0.0 0.612 B:P32851:0.082
D:P60881:0.506
A:P63045:0.106
5w5c 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 LEU C:44 C:50 102.0 0.6 H -56.2 -33.4 1.0 0.006 0.594 B:P32851:0.1
A:P63045:0.147
D:P60881:0.488
 MG
HOH
 6.408
3.885
 O
O
 MG
O
5w5d 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 LEU C:44 C:50 103.0 0.606 H -69.1 -30.0 2.0 0.012 0.594 D:P60881:0.482
B:P32851:0.1
A:P63045:0.147
 MG
HOH
 6.914
4.125
 O
C
 MG
O
6mti 5 P60881 100.0 5e-47 EM
 2019-04-24 LEU I:44 C:50 103.0 0.606 H -63.2 -39.6 1.0 0.006 0.6 J:P60881:0.494
G:P63045:0.106
H:P32851:0.076
LEU M:44 G:50 105.0 0.618 H -63.2 -39.5 0.0 0.0 0.618 N:P60881:0.5
K:P63045:0.1
L:P32851:0.088
LEU Q:44 K:50 105.0 0.618 H -63.3 -39.5 0.0 0.0 0.618 P:P32851:0.082
R:P60881:0.506
O:P63045:0.1
LEU U:44 O:50 104.0 0.612 H -63.1 -39.5 0.0 0.0 0.612 V:P60881:0.5
T:P32851:0.082
S:P63045:0.1
LEU Y:44 S:50 103.0 0.606 H -63.4 -39.4 1.0 0.006 0.6 X:P32851:0.076
W:P63045:0.1
Z:P60881:0.494
LEU CA:44 W:50 101.0 0.594 H -63.3 -39.4 0.0 0.0 0.594 BA:P32851:0.076
AA:P63045:0.094
DA:P60881:0.488
5low 2 P60881 100.0 3e-46 X-RAY
 2017-06-21 LEU D:63 D:50 95.0 0.559 H -70.6 -49.0 4.0 0.024 0.535 G:P60881:0.118
F:P60881:0.053
E:P60881:0.435
LEU F:63 F:50 100.0 0.588 H -65.2 -34.0 3.0 0.018 0.57 D:P60881:0.053
G:P60881:0.494
E:P60881:0.053
 HOH
 8.126
 O
 O
LEU K:63 K:50 86.0 0.506 H -68.3 -43.3 NA NA NA
LEU M:63 M:50 89.0 0.524 H -65.2 -47.9 NA NA NA
5lob 2 P60881 100.0 4e-46 X-RAY
 2017-06-21 LEU D:68 D:50 107.0 0.629 H -76.4 -45.9 4.0 0.024 0.605 F:P60881:0.076
G:P60881:0.141
E:P60881:0.529
 SO4
 8.870
 O
 O4
LEU F:68 F:50 101.0 0.594 H -65.7 -38.7 2.0 0.012 0.582 G:P60881:0.476
D:P60881:0.071
E:P60881:0.241
 SO4
SO4
 5.218
8.312
 O
O
 O1
O1
1jth 1 P60881 92.68 4e-46 X-RAY
 2001-11-28 LEU A:50 A:50 90.0 0.529 H -57.0 -43.5 2.0 0.012 0.517 B:P32851:0.424
D:P32851:0.082
C:P60881:0.076
 HOH
 3.505
 CD2
 O
LEU C:50 C:50 98.0 0.576 H -62.2 -32.7 0.0 0.0 0.576 B:P32851:0.112
D:P32851:0.465
A:P60881:0.071
 HOH
 3.478
 CD2
 O
3rk2 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LEU C:48 C:50 100.0 0.588 H -63.6 -38.6 1.0 0.006 0.582 D:P60880:0.482
B:P32851:0.094
A:P63027:0.135
 CA
HOH
 9.467
7.541
 N
N
 CA
O
LEU G:48 G:50 99.0 0.582 H -64.0 -36.6 NA NA NA
3rk3 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LEU C:48 C:50 109.0 0.641 H -59.2 -31.2 0.0 0.0 0.641 B:P32851:0.124
A:P63027:0.188
D:P60880:0.512
3rl0 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 LEU C:48 C:50 99.0 0.582 H -62.5 -40.7 1.0 0.006 0.576 D:P60880:0.471
A:P63027:0.094
B:P32851:0.082
LEU G:48 G:50 99.0 0.582 H -61.7 -41.1 NA NA NA
LEU K:48 K:50 99.0 0.582 H -61.8 -40.4 NA NA NA
LEU O:48 O:50 98.0 0.576 H -62.1 -40.3 NA NA NA
LEU S:48 S:50 99.0 0.582 H -61.7 -41.2 NA NA NA
LEU W:48 W:50 97.0 0.571 H -62.1 -41.0 NA NA NA
LEU AA:48 a:50 101.0 0.594 H -62.2 -40.0 NA NA NA
LEU EA:48 e:50 100.0 0.588 H -61.4 -40.7 NA NA NA
5kj7 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 LEU C:42 C:50 99.0 0.582 H -65.1 -33.6 3.0 0.018 0.564 B:P32851:0.112
A:P63025:0.1
D:P60881:0.459
 CA
 6.515
 O
 CA
LEU I:42 I:50 100.0 0.588 H -66.1 -33.2 NA NA NA
5kj8 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 LEU C:42 C:50 97.0 0.571 H -65.7 -31.8 2.0 0.012 0.559 D:P60881:0.429
A:P63025:0.165
B:P32851:0.118
 CA
 6.514
 O
 CA
LEU I:42 I:50 97.0 0.571 H -66.7 -31.0 NA NA NA
6wvw 3 P60881 98.65 1e-43 X-RAY
 2021-03-17 LEU C:41 C:50 97.0 0.571 H -64.3 -41.2 0.0 0.0 0.571 D:P60881:0.459
B:P32851:0.1
A:P63045:0.171
 CA
HOH
 6.726
6.022
 O
O
 CA
O
LEU G:41 G:50 96.0 0.565 H -64.7 -40.9 NA NA NA
1kil 3 P60880 100.0 3e-42 X-RAY
 2002-03-13 LEU C:42 C:50 97.0 0.571 H -60.0 -38.4 0.0 0.0 0.571 D:P60880:0.482
B:P32851:0.094
A:P63045:0.147
 MG
HOH
 6.033
4.427
 O
O
 MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 LEU A:50 A:50 14.0 0.082 H -67.7 -44.4