Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10273821 . G A CCDS13110.1:NM_130811.2:c.176cGc>cAc_NP_570824.1:p.59R>H Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 95.59 1e-141 EM
 2018-09-19 ARG G:62 H:59 134.0 0.596 H -73.7 -21.1 13.0 0.058 0.538 J:P54921:0.476
H:P32851:0.116
6mdn 2 P60881 95.59 1e-141 EM
 2018-09-19 ARG G:62 H:59 144.0 0.64 H -77.7 -22.9 7.0 0.031 0.609 J:P54921:0.529
H:P32851:0.142
6mdo 2 P60881 95.59 1e-141 EM
 2018-09-19 ARG G:62 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 95.59 1e-141 EM
 2018-09-19 ARG G:62 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 96.97 1e-140 EM
 2015-01-28 ARG M:53 M:59 184.0 0.818 H -81.8 -28.1 69.0 0.307 0.511 I:P54921:0.098
L:P32851:0.16
J:P54921:0.276
3j96 5 ? 96.81 2e-133 EM
 2015-01-28 ARG M:43 M:59 157.0 0.698 T -98.7 -20.2 46.0 0.204 0.494 L:P32851:0.324
J:P54921:0.244
3j98 5 ? 96.81 2e-133 EM
 2015-01-28 ARG M:43 M:59 147.0 0.653 H -79.6 -19.0 56.0 0.249 0.404 I:P54921:0.027
L:P32851:0.178
J:P54921:0.227
3j99 5 ? 96.81 2e-133 EM
 2015-01-28 ARG M:43 M:59 144.0 0.64 H -79.6 -19.0 69.0 0.307 0.333 L:P32851:0.178
J:P54921:0.178
6ip1 3 P60881 100.0 1e-66 EM
 2019-04-24 ARG C:61 C:59 179.0 0.796 H -67.6 -28.7 35.0 0.156 0.64 B:P32851:0.16
F:A5D7S0:0.52
1jth 1 P60881 100.0 1e-49 X-RAY
 2001-11-28 ARG A:59 A:59 166.0 0.738 H -72.8 -39.8 146.0 0.649 0.089 D:P32851:0.089
 HOH
 7.079
 O
 O
ARG C:59 C:59 148.0 0.658 H -66.9 -42.6 119.0 0.529 0.129 B:P32851:0.129
 HOH
 3.116
 CD
 O
1sfc 3 P60881 92.77 9e-47 X-RAY
 1998-10-28 ARG C:59 C:59 171.0 0.76 H -61.3 -33.4 138.0 0.613 0.147 B:P32851:0.147
 SR
HOH
 9.251
9.366
 N
N
 SR
O
ARG G:59 G:59 119.0 0.529 H -66.9 -35.8 NA NA NA
ARG K:59 K:59 136.0 0.604 H -72.2 -47.0 NA NA NA
1urq 3 P13795 89.87 1e-42 X-RAY
 2004-08-26 ARG C:56 C:59 140.0 0.622 H -64.6 -37.8 102.0 0.453 0.169 B:P32851:0.169
 HOH
 3.180
 CG
 O
3hd7 3 P60881 89.87 1e-42 X-RAY
 2009-07-14 ARG C:56 C:59 141.0 0.627 H -67.3 -49.0 117.0 0.52 0.107 B:P32851:0.107
ARG G:56 G:59 137.0 0.609 H -63.2 -60.6 NA NA NA
3ipd 3 P60881 89.87 1e-42 X-RAY
 2009-09-01 ARG C:56 C:59 162.0 0.72 H -58.2 -42.7 113.0 0.502 0.218 B:P32851:0.218
ARG G:56 G:59 163.0 0.724 H -58.4 -42.4 NA NA NA
1n7s 3 P60881 92.21 2e-42 X-RAY
 2002-12-27 ARG C:55 C:59 141.0 0.627 H -67.6 -35.3 90.0 0.4 0.227 B:P32851:0.227
 HOH
 2.702
 O
 O
2n1t 3 P60880 92.21 2e-42 NMR
 2015-06-03 ARG C:53 C:59 166.0 0.738 H -61.2 -39.5 104.0 0.462 0.276 B:P32851:0.276
5ccg 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ARG C:53 C:59 173.0 0.769 H -64.8 -34.1 82.0 0.364 0.405 B:P32851:0.253
E:P21707:0.187
 CA
CA
HOH
 7.696
7.280
6.869
 N
N
NH2
 CA
CA
O
ARG I:53 I:59 147.0 0.653 H -63.8 -34.8 NA NA NA
5cch 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ARG C:53 C:59 144.0 0.64 H -58.6 -39.2 54.0 0.24 0.4 B:P32851:0.133
E:P21707:0.316
5cci 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ARG C:53 C:59 161.0 0.716 H -59.0 -37.9 68.0 0.302 0.414 B:P32851:0.16
E:P21707:0.289
5w5c 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 ARG C:53 C:59 159.0 0.707 H -57.3 -33.3 131.0 0.582 0.125 B:P32851:0.124
 MG
HOH
 8.344
4.505
 N
NH1
 MG
O
5w5d 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 ARG C:53 C:59 162.0 0.72 H -72.7 -26.4 142.0 0.631 0.089 B:P32851:0.089
 MG
HOH
 8.581
2.366
 N
NE
 MG
O
6mti 5 P60881 92.21 2e-42 EM
 2019-04-24 ARG I:53 C:59 158.0 0.702 H -59.0 -37.9 59.0 0.262 0.44 C:P21707:0.351
H:P32851:0.151
ARG M:53 G:59 156.0 0.693 H -58.9 -37.9 55.0 0.244 0.449 B:P21707:0.373
L:P32851:0.142
ARG Q:53 K:59 160.0 0.711 H -59.0 -37.9 127.0 0.564 0.147 P:P32851:0.147
ARG U:53 O:59 162.0 0.72 H -59.0 -37.9 58.0 0.258 0.462 D:P21707:0.382
T:P32851:0.151
ARG Y:53 S:59 157.0 0.698 H -59.0 -38.0 59.0 0.262 0.436 E:P21707:0.338
X:P32851:0.147
ARG CA:53 W:59 160.0 0.711 H -59.0 -37.9 125.0 0.556 0.155 BA:P32851:0.156
5low 2 P60881 92.11 8e-42 X-RAY
 2017-06-21 ARG D:72 D:59 162.0 0.72 H -67.6 -35.9 86.0 0.382 0.338 A:P47709:0.151
F:P60881:0.187
 HOH
 5.561
 N
 O
ARG F:72 F:59 132.0 0.587 H -62.5 -31.3 117.0 0.52 0.067 D:P60881:0.053
B:P47709:0.009
 HOH
 3.183
 CG
 O
ARG K:72 K:59 152.0 0.676 H -67.1 -34.7 NA NA NA
ARG M:72 M:59 150.0 0.667 H -67.6 -30.6 NA NA NA
5lob 2 P60881 92.11 9e-42 X-RAY
 2017-06-21 ARG D:77 D:59 122.0 0.542 H -70.8 -26.8 96.0 0.427 0.115 F:P60881:0.062
A:P47709:0.053
 SO4
 6.318
 NH2
 O2
ARG F:77 F:59 170.0 0.756 H -65.9 -36.4 98.0 0.436 0.32 D:P60881:0.107
B:P47709:0.213
 SO4
SO4
 8.300
8.449
 N
N
 O1
O3
3rk2 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ARG C:57 C:59 143.0 0.636 H -58.9 -43.5 117.0 0.52 0.116 B:P32851:0.116
 CA
HOH
 8.037
2.683
 NH2
NH1
 CA
O
ARG G:57 G:59 145.0 0.644 H -60.7 -43.1 NA NA NA
3rk3 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ARG C:57 C:59 148.0 0.658 H -67.1 -40.4 112.0 0.498 0.16 B:P32851:0.16
3rl0 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ARG C:57 C:59 156.0 0.693 H -70.6 -28.2 136.0 0.604 0.089 B:P32851:0.089
ARG G:57 G:59 158.0 0.702 H -71.6 -27.8 NA NA NA
ARG K:57 K:59 154.0 0.684 H -71.0 -28.3 NA NA NA
ARG O:57 O:59 156.0 0.693 H -71.8 -27.9 NA NA NA
ARG S:57 S:59 154.0 0.684 H -71.1 -28.3 NA NA NA
ARG W:57 W:59 157.0 0.698 H -71.2 -27.6 NA NA NA
ARG AA:57 a:59 155.0 0.689 H -71.8 -27.6 NA NA NA
ARG EA:57 e:59 156.0 0.693 H -71.6 -28.3 NA NA NA
5kj7 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 ARG C:51 C:59 168.0 0.747 H -66.9 -28.1 79.0 0.351 0.396 B:P32851:0.262
E:P21707:0.169
 CA
CA
HOH
 7.594
7.052
6.601
 N
N
NH2
 CA
CA
O
ARG I:51 I:59 149.0 0.662 H -63.4 -36.2 NA NA NA
5kj8 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 ARG C:51 C:59 162.0 0.72 H -60.7 -36.8 61.0 0.271 0.449 E:P21707:0.284
B:P32851:0.209
 CA
CA
 7.769
7.450
 N
N
 CA
CA
ARG I:51 I:59 140.0 0.622 H -59.2 -37.2 NA NA NA
6wvw 3 P60881 90.54 5e-39 X-RAY
 2021-03-17 PRO C:50 C:59 79.0 0.545 H -61.3 -23.9 61.0 0.421 0.124 B:P32851:0.124
 CA
CA
HOH
 8.740
6.488
2.771
 HB2
HD2
HD3
 CA
CA
O
PRO G:50 G:59 69.0 0.476 H -61.6 -22.8 NA NA NA
1kil 3 P60880 91.55 1e-37 X-RAY
 2002-03-13 ARG C:51 C:59 153.0 0.68 H -64.7 -36.3 126.0 0.56 0.12 B:P32851:0.12
 MG
HOH
 8.942
3.654
 N
CG
 MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 100.0 1e-150 ARG A:59 A:59 134.0 0.596 H -59.5 -36.4