Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10273845 . T A CCDS13110.1:NM_130811.2:c.200aTc>aAc_NP_570824.1:p.67I>N Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 95.59 1e-141 EM
 2018-09-19 ILE G:70 H:67 77.0 0.44 H -62.2 -49.4 18.0 0.103 0.337 H:P32851:0.337
6mdn 2 P60881 95.59 1e-141 EM
 2018-09-19 ILE G:70 H:67 77.0 0.44 H -63.5 -45.4 14.0 0.08 0.36 H:P32851:0.349
I:P63045:0.011
6mdo 2 P60881 95.59 1e-141 EM
 2018-09-19 ILE G:70 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 95.59 1e-141 EM
 2018-09-19 ILE G:70 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 96.97 1e-140 EM
 2015-01-28 ILE M:61 M:67 76.0 0.434 H -73.6 -36.9 6.0 0.034 0.4 L:P32851:0.326
K:P63045:0.074
3j96 5 ? 96.81 2e-133 EM
 2015-01-28 ILE M:51 M:67 59.0 0.337 H -66.7 -42.1 0.0 0.0 0.337 L:P32851:0.286
K:P63045:0.091
3j98 5 ? 96.81 2e-133 EM
 2015-01-28 ILE M:51 M:67 68.0 0.389 H -71.7 -36.4 3.0 0.017 0.372 L:P32851:0.314
K:P63045:0.08
3j99 5 ? 96.81 2e-133 EM
 2015-01-28 ILE M:51 M:67 67.0 0.383 H -71.7 -36.3 3.0 0.017 0.366 L:P32851:0.309
K:P63045:0.086
6ip1 3 P60881 100.0 1e-66 EM
 2019-04-24 ILE C:69 C:67 75.0 0.429 T -72.0 -10.6 1.0 0.006 0.423 D:P60881:0.029
B:P32851:0.36
A:P63045:0.074
1jth 1 P60881 100.0 1e-49 X-RAY
 2001-11-28 ILE A:67 A:67 93.0 0.531 H -58.3 -50.3 0.0 0.0 0.531 B:P32851:0.074
D:P32851:0.4
C:P60881:0.257
 HOH
 8.803
 N
 O
ILE C:67 C:67 69.0 0.394 H -56.0 -49.0 0.0 0.0 0.394 B:P32851:0.343
D:P32851:0.023
A:P60881:0.126
 HOH
 5.068
 N
 O
1sfc 3 P60881 92.77 9e-47 X-RAY
 1998-10-28 ILE C:67 C:67 96.0 0.549 H -54.8 -44.7 0.0 0.0 0.549 B:P32851:0.354
D:P60881:0.189
A:P63045:0.177
ILE G:67 G:67 101.0 0.577 H -67.0 -30.5 NA NA NA
ILE K:67 K:67 96.0 0.549 H -64.8 -34.8 NA NA NA
1urq 3 P13795 89.87 1e-42 X-RAY
 2004-08-26 ILE C:64 C:67 105.0 0.6 H -56.2 -44.8 0.0 0.0 0.6 B:P32851:0.4
D:P13795:0.211
A:Q9Z152:0.171
 HOH
 3.759
 CA
 O
3hd7 3 P60881 89.87 1e-42 X-RAY
 2009-07-14 ILE C:64 C:67 92.0 0.526 H -50.5 -38.7 0.0 0.0 0.526 B:P32851:0.371
D:P60881:0.149
A:P63045:0.103
 SO4
 7.438
 O
 O2
ILE G:64 G:67 87.0 0.497 H -50.3 -54.5 NA NA NA
3ipd 3 P60881 89.87 1e-42 X-RAY
 2009-09-01 ILE C:64 C:67 92.0 0.526 H -67.1 -57.1 8.0 0.046 0.48 B:P32851:0.366
A:P63045:0.063
D:P60881:0.057
ILE G:64 G:67 92.0 0.526 H -67.8 -56.3 NA NA NA
1n7s 3 P60881 92.21 2e-42 X-RAY
 2002-12-27 ILE C:63 C:67 92.0 0.526 H -61.4 -44.1 0.0 0.0 0.526 A:P63045:0.109
B:P32851:0.343
D:P60881:0.2
 HOH
 3.678
 CA
 O
2n1t 3 P60880 92.21 2e-42 NMR
 2015-06-03 ILE C:61 C:67 105.0 0.6 H -60.1 -44.3 1.0 0.006 0.594 A:P63045:0.126
B:P32851:0.383
D:P60880:0.194
5ccg 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ILE C:61 C:67 97.0 0.554 H -55.5 -43.6 1.0 0.006 0.548 B:P32851:0.429
D:P60881:0.12
A:P63045:0.08
ILE I:61 I:67 99.0 0.566 H -55.9 -45.4 NA NA NA
5cch 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ILE C:61 C:67 95.0 0.543 H -63.5 -41.3 0.0 0.0 0.543 B:P32851:0.383
D:P60881:0.154
A:P63045:0.12
5cci 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 ILE C:61 C:67 90.0 0.514 H -57.1 -45.7 2.0 0.011 0.503 B:P32851:0.337
D:P60881:0.137
A:P63045:0.109
5w5c 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 ILE C:61 C:67 108.0 0.617 H -63.3 -41.1 13.0 0.074 0.543 B:P32851:0.4
D:P60881:0.137
5w5d 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 ILE C:61 C:67 100.0 0.571 H -64.6 -40.9 27.0 0.154 0.417 D:P60881:0.023
B:P32851:0.394
6mti 5 P60881 92.21 2e-42 EM
 2019-04-24 ILE I:61 C:67 90.0 0.514 H -57.1 -45.6 2.0 0.011 0.503 J:P60881:0.131
G:P63045:0.097
H:P32851:0.343
ILE M:61 G:67 90.0 0.514 H -57.1 -45.7 2.0 0.011 0.503 N:P60881:0.131
K:P63045:0.109
L:P32851:0.331
ILE Q:61 K:67 88.0 0.503 H -57.1 -45.7 2.0 0.011 0.492 P:P32851:0.331
R:P60881:0.126
O:P63045:0.109
ILE U:61 O:67 89.0 0.509 H -57.0 -45.8 1.0 0.006 0.503 V:P60881:0.131
T:P32851:0.337
S:P63045:0.109
ILE Y:61 S:67 90.0 0.514 H -57.0 -45.7 2.0 0.011 0.503 X:P32851:0.343
W:P63045:0.103
Z:P60881:0.126
ILE CA:61 W:67 89.0 0.509 H -57.0 -45.7 2.0 0.011 0.498 BA:P32851:0.337
AA:P63045:0.097
DA:P60881:0.131
5low 2 P60881 92.11 8e-42 X-RAY
 2017-06-21 ILE D:80 D:67 115.0 0.657 H -73.8 -9.8 30.0 0.171 0.486 F:P60881:0.383
E:P60881:0.114
 HOH
 9.024
 O
 O
ILE F:80 F:67 102.0 0.583 H -66.4 -40.4 2.0 0.011 0.572 D:P60881:0.554
G:P60881:0.114
 HOH
 5.120
 N
 O
ILE K:80 K:67 82.0 0.469 H -69.0 -32.3 NA NA NA
ILE M:80 M:67 97.0 0.554 H -59.6 -32.9 NA NA NA
5lob 2 P60881 92.11 9e-42 X-RAY
 2017-06-21 ILE D:85 D:67 95.0 0.543 H -79.3 -35.4 1.0 0.006 0.537 F:P60881:0.491
E:P60881:0.114
ILE F:85 F:67 100.0 0.571 H -68.2 -39.6 1.0 0.006 0.565 G:P60881:0.114
D:P60881:0.497
3rk2 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ILE C:65 C:67 97.0 0.554 H -52.9 -50.9 6.0 0.034 0.52 D:P60880:0.194
B:P32851:0.354
 HOH
 6.600
 N
 O
ILE G:65 G:67 98.0 0.56 H -62.2 -46.1 NA NA NA
3rk3 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ILE C:65 C:67 98.0 0.56 H -61.5 -51.3 19.0 0.109 0.451 B:P32851:0.28
D:P60880:0.171
3rl0 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 ILE C:65 C:67 102.0 0.583 H -57.9 -44.9 7.0 0.04 0.543 D:P60880:0.183
B:P32851:0.377
ILE G:65 G:67 100.0 0.571 H -58.1 -45.2 NA NA NA
ILE K:65 K:67 102.0 0.583 H -57.5 -44.6 NA NA NA
ILE O:65 O:67 102.0 0.583 H -58.1 -44.5 NA NA NA
ILE S:65 S:67 103.0 0.589 H -58.1 -44.9 NA NA NA
ILE W:65 W:67 101.0 0.577 H -57.8 -44.9 NA NA NA
ILE AA:65 a:67 100.0 0.571 H -58.1 -44.4 NA NA NA
ILE EA:65 e:67 101.0 0.577 H -57.3 -44.8 NA NA NA
5kj7 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 ILE C:59 C:67 97.0 0.554 H -57.9 -40.4 1.0 0.006 0.548 B:P32851:0.429
A:P63025:0.063
D:P60881:0.12
ILE I:59 I:67 100.0 0.571 H -58.5 -41.7 NA NA NA
5kj8 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 ILE C:59 C:67 97.0 0.554 H -58.7 -42.5 0.0 0.0 0.554 D:P60881:0.126
A:P63025:0.074
B:P32851:0.429
ILE I:59 I:67 100.0 0.571 H -60.2 -44.3 NA NA NA
6wvw 3 P60881 90.54 5e-39 X-RAY
 2021-03-17 ILE C:58 C:67 96.0 0.549 H -61.2 -42.6 0.0 0.0 0.549 D:P60881:0.189
B:P32851:0.366
A:P63045:0.103
 HOH
 2.981
 HA
 O
ILE G:58 G:67 95.0 0.543 H -58.8 -43.7 NA NA NA
1kil 3 P60880 91.55 1e-37 X-RAY
 2002-03-13 ILE C:59 C:67 98.0 0.56 H -55.7 -45.1 0.0 0.0 0.56 D:P60880:0.211
B:P32851:0.366
A:P63045:0.137
 HOH
 5.432
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 100.0 1e-150 ILE A:67 A:67 58.0 0.331 H -56.6 -39.8