Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10280028 . C A CCDS13109.1:NM_003081.3:c.520Cag>Aag_NP_003072.2:p.174Q>K Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:177 H:174 29.0 0.161 H -66.9 -29.5 28.0 0.156 0.005 J:P54921:0.006
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:177 H:174 37.0 0.206 H -69.2 -31.7 28.0 0.156 0.05 J:P54921:0.05
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:177 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:177 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 GLN M:168 M:174 23.0 0.128 H -67.8 -53.5 6.0 0.033 0.095 L:P32851:0.006
K:P63045:0.094
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:158 M:174 14.0 0.078 H -57.4 -42.6 7.0 0.039 0.039 L:P32851:0.006
K:P63045:0.033
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:158 M:174 20.0 0.111 H -87.2 -36.0 0.0 0.0 0.111 L:P32851:0.006
K:P63045:0.106
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:158 M:174 21.0 0.117 H -87.3 -36.1 0.0 0.0 0.117 L:P32851:0.011
K:P63045:0.111
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 GLN D:55 D:174 85.0 0.472 H -61.3 -44.4 4.0 0.022 0.45 B:P32851:0.05
C:P60881:0.389
A:P63045:0.183
 SR
HOH
 4.992
3.731
 CG
CG
 SR
O
GLN H:55 H:174 92.0 0.511 H -70.5 -37.2 NA NA NA
GLN L:55 L:174 92.0 0.511 H -68.5 -33.5 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 GLN D:51 D:174 89.0 0.494 H -68.9 -33.0 0.0 0.0 0.494 B:P32851:0.022
C:P60881:0.439
A:P63045:0.167
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 GLN D:44 D:174 115.0 0.639 H -62.4 -41.8 14.0 0.078 0.561 A:P63045:0.183
C:P60880:0.489
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 GLN D:36 D:174 89.0 0.494 H -68.6 -31.4 1.0 0.006 0.488 B:P32851:0.061
C:P60881:0.433
A:P63045:0.217
 HOH
 3.333
 CB
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 GLN D:34 D:174 97.0 0.539 H -70.7 -28.4 0.0 0.0 0.539 A:P63025:0.233
B:P32851:0.056
C:P60881:0.461
 CA
CA
 5.346
9.898
 CG
O
 CA
CA
GLN J:34 J:174 91.0 0.506 H -70.3 -26.8 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 GLN D:34 D:174 97.0 0.539 H -70.3 -25.6 0.0 0.0 0.539 A:P63025:0.217
B:P32851:0.044
C:P60881:0.467
 CA
 5.102
 NE2
 CA
GLN J:34 J:174 94.0 0.522 H -70.0 -26.6 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 GLN D:34 D:174 91.0 0.506 H -68.2 -33.0 2.0 0.011 0.495 B:P32851:0.039
C:P60881:0.428
A:P63045:0.217
 CA
HOH
 4.579
2.743
 HG2
HA
 CA
O
GLN H:34 H:174 93.0 0.517 H -66.9 -33.0 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 GLN D:38 D:174 92.0 0.511 H -69.4 -34.1 1.0 0.006 0.505 B:P32851:0.05
C:P60881:0.411
A:P63045:0.206
GLN H:38 H:174 97.0 0.539 H -75.3 -26.4 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 GLN D:38 D:174 117.0 0.65 H -66.9 -45.4 9.0 0.05 0.6 B:P32851:0.028
A:P63045:0.233
C:P60881:0.494
GLN H:38 H:174 119.0 0.661 H -67.4 -45.5 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:35 D:174 96.0 0.533 H -69.3 -30.0 0.0 0.0 0.533 B:P32851:0.05
C:P60881:0.467
A:P63045:0.233
 CA
CA
 5.402
9.837
 CG
CA
 CA
CA
GLN J:35 J:174 92.0 0.511 H -69.1 -29.1 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:35 D:174 112.0 0.622 H -70.7 -28.6 13.0 0.072 0.55 B:P32851:0.056
C:P60881:0.489
A:P63045:0.194
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:35 D:174 99.0 0.55 H -66.5 -32.1 6.0 0.033 0.517 B:P32851:0.028
C:P60881:0.456
A:P63045:0.183
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 GLN D:35 D:174 90.0 0.5 H -69.9 -31.7 1.0 0.006 0.494 B:P32851:0.05
C:P60881:0.439
A:P63045:0.2
 MG
HOH
 5.185
3.269
 CG
CB
 MG
O
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 GLN D:35 D:174 88.0 0.489 H -67.6 -24.9 0.0 0.0 0.489 B:P32851:0.039
C:P60881:0.439
A:P63045:0.189
 MG
HOH
 5.530
3.396
 NE2
C
 MG
O
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 GLN J:35 D:174 98.0 0.544 H -66.5 -32.1 7.0 0.039 0.505 G:P63045:0.183
H:P32851:0.028
I:P60881:0.444
GLN N:35 H:174 99.0 0.55 H -66.4 -32.2 8.0 0.044 0.506 L:P32851:0.028
M:P60881:0.444
K:P63045:0.183
GLN R:35 L:174 97.0 0.539 H -66.6 -32.1 7.0 0.039 0.5 Q:P60881:0.439
P:P32851:0.028
O:P63045:0.183
GLN V:35 P:174 98.0 0.544 H -66.4 -32.1 6.0 0.033 0.511 T:P32851:0.033
S:P63045:0.189
U:P60881:0.45
GLN Z:35 T:174 98.0 0.544 H -66.5 -32.1 6.0 0.033 0.511 W:P63045:0.183
Y:P60881:0.444
X:P32851:0.028
GLN DA:35 X:174 96.0 0.533 H -66.5 -32.1 6.0 0.033 0.5 AA:P63045:0.183
BA:P32851:0.028
CA:P60881:0.439
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 GLN D:39 D:173 83.0 0.461 H -69.7 -34.7 1.0 0.006 0.455 B:P32851:0.05
C:P13795:0.383
A:Q9Z152:0.222
 HOH
 3.792
 NE2
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 GLN E:53 E:174 88.0 0.489 H -71.4 -36.0 0.0 0.0 0.489 D:P60881:0.483
G:P60881:0.028
 HOH
 5.529
 O
 O
GLN G:53 G:174 92.0 0.511 H -63.7 -42.0 3.0 0.017 0.494 D:P60881:0.006
F:P60881:0.483
E:P60881:0.078
 HOH
 8.125
 C
 O
GLN L:53 L:174 76.0 0.422 H -68.1 -37.5 NA NA NA
GLN N:53 N:174 88.0 0.489 H -69.5 -33.2 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:36 D:174 91.0 0.506 H -62.9 -31.3 0.0 0.0 0.506 B:P32851:0.05
C:P60880:0.433
A:P63027:0.222
 HOH
 7.638
 N
 O
GLN H:36 H:174 86.0 0.478 H -60.5 -32.5 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:36 D:174 97.0 0.539 H -59.5 -40.9 5.0 0.028 0.511 A:P63027:0.217
C:P60880:0.45
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:36 D:174 100.0 0.556 H -70.0 -34.3 6.0 0.033 0.523 B:P32851:0.044
A:P63027:0.211
C:P60880:0.433
GLN H:36 H:174 102.0 0.567 H -69.9 -35.0 NA NA NA
GLN L:36 L:174 99.0 0.55 H -71.2 -33.9 NA NA NA
GLN P:36 P:174 98.0 0.544 H -71.1 -33.7 NA NA NA
GLN T:36 T:174 102.0 0.567 H -70.3 -34.0 NA NA NA
GLN X:36 X:174 99.0 0.55 H -70.3 -34.3 NA NA NA
GLN BA:36 b:174 98.0 0.544 H -71.2 -33.9 NA NA NA
GLN FA:36 f:174 101.0 0.561 H -70.8 -34.1 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 GLN E:67 E:174 87.0 0.483 H -71.8 -33.0 5.0 0.028 0.455 D:P60881:0.439
G:P60881:0.067
 SO4
 9.784
 NE2
 O4
GLN G:67 G:174 90.0 0.5 H -71.0 -33.6 1.0 0.006 0.494 E:P60881:0.106
F:P60881:0.45
 SO4
SO4
 4.656
5.610
 NE2
CG
 O4
O1
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 GLN D:36 D:174 84.0 0.467 H -59.3 -38.3 2.0 0.011 0.456 B:P32851:0.044
C:P60880:0.394
A:P63045:0.194
 MG
HOH
 5.082
3.237
 NE2
NE2
 MG
O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 GLN B:29 B:174 169.0 0.939 S -75.2 151.4 134.0 0.744 0.195 A:33321098:0.194
 HOH
 2.464
 OE1
 O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 GLN A:480 NA:NA DO NA DO DO DO NA NA NA
GLN B:480 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 GLN A:174 A:174 11.0 0.061 H -62.7 -40.3