Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 10280037 | . | C | A | CCDS13109.1:NM_003081.3:c.529Cag>Aag_NP_003072.2:p.177Q>K | Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6mdm | 2 | P60881 | 100.0 | 2e-149 |
EM |
2018-09-19 | GLN | G:180 | H:177 | 31.0 | 0.172 | H | -63.0 | -38.9 | 31.0 | 0.172 | 0.0 | ||||||
6mdn | 2 | P60881 | 100.0 | 2e-149 |
EM |
2018-09-19 | GLN | G:180 | H:177 | 39.0 | 0.217 | H | -64.3 | -33.9 | 39.0 | 0.217 | 0.0 | ||||||
6mdo | 2 | P60881 | 100.0 | 2e-149 |
EM |
2018-09-19 | GLN | G:180 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
6mdp | 2 | P60881 | 100.0 | 2e-149 |
EM |
2018-09-19 | GLN | G:180 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
3j97 | 5 | ? | 98.48 | 1e-141 |
EM |
2015-01-28 | GLN | M:171 | M:177 | 14.0 | 0.078 | H | -85.5 | -37.0 | 14.0 | 0.078 | 0.0 | ||||||
3j96 | 5 | ? | 98.4 | 3e-134 |
EM |
2015-01-28 | GLN | M:161 | M:177 | 21.0 | 0.117 | H | -63.2 | -38.4 | 12.0 | 0.067 | 0.05 |
I:P54921:0.05 |
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3j98 | 5 | ? | 98.4 | 3e-134 |
EM |
2015-01-28 | GLN | M:161 | M:177 | 8.0 | 0.044 | H | -72.4 | -39.8 | 5.0 | 0.028 | 0.016 |
I:P54921:0.017 |
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3j99 | 5 | ? | 98.4 | 3e-134 |
EM |
2015-01-28 | GLN | M:161 | M:177 | 7.0 | 0.039 | H | -72.5 | -39.7 | 7.0 | 0.039 | 0.0 | ||||||
1sfc | 4 | P60881 | 100.0 | 1e-56 |
X-RAY |
1998-10-28 | GLN | D:58 | D:177 | 86.0 | 0.478 | H | -52.9 | -53.3 | 13.0 | 0.072 | 0.406 |
C:P60881:0.406 |
SR HOH |
4.689 2.878 |
OE1 OE1 |
SR O |
|
GLN | H:58 | H:177 | 90.0 | 0.5 | H | -63.6 | -46.0 | NA | NA | NA | |||||||||||||
GLN | L:58 | L:177 | 88.0 | 0.489 | H | -73.4 | -42.9 | NA | NA | NA | |||||||||||||
6ip1 | 4 | P60881 | 100.0 | 2e-52 |
EM |
2019-04-24 | GLN | D:54 | D:177 | 95.0 | 0.528 | H | -76.1 | -34.3 | 16.0 | 0.089 | 0.439 |
C:P60881:0.439 |
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2n1t | 4 | P60880 | 100.0 | 6e-47 |
NMR |
2015-06-03 | GLN | D:47 | D:177 | 76.0 | 0.422 | H | -62.4 | -35.2 | 33.0 | 0.183 | 0.239 |
C:P60880:0.239 |
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1n7s | 4 | P60881 | 100.0 | 9e-39 |
X-RAY |
2002-12-27 | GLN | D:39 | D:177 | 86.0 | 0.478 | H | -66.4 | -39.9 | 11.0 | 0.061 | 0.417 |
C:P60881:0.417 |
HOH |
2.632 |
OE1 |
O |
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5kj7 | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2016-10-19 | GLN | D:37 | D:177 | 85.0 | 0.472 | H | -60.1 | -40.2 | 16.0 | 0.089 | 0.383 |
C:P60881:0.383 |
CA CA |
3.687 4.893 |
OE1 NE2 |
CA CA |
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GLN | J:37 | J:177 | 93.0 | 0.517 | H | -60.5 | -38.1 | NA | NA | NA | |||||||||||||
5kj8 | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2016-10-19 | GLN | D:37 | D:177 | 83.0 | 0.461 | H | -60.6 | -43.0 | 18.0 | 0.1 | 0.361 |
C:P60881:0.361 |
CA CA |
3.797 6.097 |
OE1 NE2 |
CA CA |
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GLN | J:37 | J:177 | 87.0 | 0.483 | H | -61.0 | -40.2 | NA | NA | NA | |||||||||||||
6wvw | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2021-03-17 | GLN | D:37 | D:177 | 92.0 | 0.511 | H | -62.9 | -40.1 | 14.0 | 0.078 | 0.433 |
C:P60881:0.433 |
CA HOH |
2.942 2.829 |
OE1 OE1 |
CA O |
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GLN | H:37 | H:177 | 91.0 | 0.506 | H | -62.8 | -40.2 | NA | NA | NA | |||||||||||||
3hd7 | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2009-07-14 | GLN | D:41 | D:177 | 90.0 | 0.5 | H | -67.0 | -55.1 | 14.0 | 0.078 | 0.422 |
C:P60881:0.422 |
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GLN | H:41 | H:177 | 88.0 | 0.489 | H | -67.3 | -53.9 | NA | NA | NA | |||||||||||||
3ipd | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2009-09-01 | GLN | D:41 | D:177 | 92.0 | 0.511 | H | -63.3 | -55.2 | 23.0 | 0.128 | 0.383 |
C:P60881:0.383 |
|||||
GLN | H:41 | H:177 | 94.0 | 0.522 | H | -63.5 | -54.7 | NA | NA | NA | |||||||||||||
5ccg | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2015-08-12 | GLN | D:38 | D:177 | 84.0 | 0.467 | H | -58.8 | -41.1 | 16.0 | 0.089 | 0.378 |
C:P60881:0.378 |
CA CA |
3.773 5.036 |
OE1 NE2 |
CA CA |
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GLN | J:38 | J:177 | 91.0 | 0.506 | H | -59.5 | -39.4 | NA | NA | NA | |||||||||||||
5cch | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2015-08-12 | GLN | D:38 | D:177 | 96.0 | 0.533 | H | -58.9 | -47.7 | 19.0 | 0.106 | 0.427 |
C:P60881:0.428 |
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5cci | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2015-08-12 | GLN | D:38 | D:177 | 104.0 | 0.578 | H | -61.3 | -40.2 | 23.0 | 0.128 | 0.45 |
C:P60881:0.45 |
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5w5c | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2017-08-23 | GLN | D:38 | D:177 | 93.0 | 0.517 | H | -68.6 | -41.0 | 12.0 | 0.067 | 0.45 |
C:P60881:0.45 |
MG HOH |
4.351 2.531 |
OE1 OE1 |
MG O |
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5w5d | 4 | P60881 | 100.0 | 1e-38 |
X-RAY |
2017-08-23 | GLN | D:38 | D:177 | 86.0 | 0.478 | H | -63.4 | -45.7 | 11.0 | 0.061 | 0.417 |
C:P60881:0.417 |
MG HOH |
4.673 2.916 |
OE1 OE1 |
MG O |
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6mti | 6 | P60881 | 100.0 | 1e-38 |
EM |
2019-04-24 | GLN | J:38 | D:177 | 101.0 | 0.561 | H | -61.3 | -40.2 | 24.0 | 0.133 | 0.428 |
I:P60881:0.428 |
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GLN | N:38 | H:177 | 104.0 | 0.578 | H | -61.4 | -40.1 | 23.0 | 0.128 | 0.45 |
M:P60881:0.45 |
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GLN | R:38 | L:177 | 104.0 | 0.578 | H | -61.3 | -40.3 | 23.0 | 0.128 | 0.45 |
Q:P60881:0.45 |
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GLN | V:38 | P:177 | 105.0 | 0.583 | H | -61.4 | -40.2 | 23.0 | 0.128 | 0.455 |
U:P60881:0.456 |
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GLN | Z:38 | T:177 | 102.0 | 0.567 | H | -61.3 | -40.2 | 23.0 | 0.128 | 0.439 |
Y:P60881:0.439 |
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GLN | DA:38 | X:177 | 103.0 | 0.572 | H | -61.3 | -40.3 | 25.0 | 0.139 | 0.433 |
CA:P60881:0.433 |
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1urq | 4 | P13795 | 98.44 | 2e-38 |
X-RAY |
2004-08-26 | GLN | D:42 | D:176 | 91.0 | 0.506 | H | -64.0 | -42.1 | 16.0 | 0.089 | 0.417 |
C:P13795:0.417 |
HOH |
2.506 |
OE1 |
O |
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5low | 3 | P60881 | 100.0 | 6e-38 |
X-RAY |
2017-06-21 | GLN | E:56 | E:177 | 105.0 | 0.583 | H | -61.8 | -37.0 | 13.0 | 0.072 | 0.511 |
D:P60881:0.511 |
HOH |
4.972 |
NE2 |
O |
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GLN | G:56 | G:177 | 91.0 | 0.506 | H | -64.8 | -41.5 | 25.0 | 0.139 | 0.367 |
F:P60881:0.367 |
HOH |
6.662 |
CG |
O |
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GLN | L:56 | L:177 | 117.0 | 0.65 | H | -71.1 | -46.9 | NA | NA | NA | |||||||||||||
GLN | N:56 | N:177 | 93.0 | 0.517 | H | -62.9 | -32.9 | NA | NA | NA | |||||||||||||
3rk2 | 4 | P60880 | 100.0 | 8e-38 |
X-RAY |
2011-07-27 | GLN | D:39 | D:177 | 89.0 | 0.494 | H | -65.8 | -44.0 | 11.0 | 0.061 | 0.433 |
C:P60880:0.433 |
HOH |
5.459 |
N |
O |
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GLN | H:39 | H:177 | 89.0 | 0.494 | H | -75.1 | -41.9 | NA | NA | NA | |||||||||||||
3rk3 | 4 | P60880 | 100.0 | 8e-38 |
X-RAY |
2011-07-27 | GLN | D:39 | D:177 | 97.0 | 0.539 | H | -60.5 | -41.7 | 13.0 | 0.072 | 0.467 |
C:P60880:0.467 |
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3rl0 | 4 | P60880 | 100.0 | 8e-38 |
X-RAY |
2011-07-27 | GLN | D:39 | D:177 | 93.0 | 0.517 | H | -60.6 | -41.4 | 9.0 | 0.05 | 0.467 |
C:P60880:0.467 |
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GLN | H:39 | H:177 | 93.0 | 0.517 | H | -59.9 | -41.2 | NA | NA | NA | |||||||||||||
GLN | L:39 | L:177 | 94.0 | 0.522 | H | -59.8 | -42.2 | NA | NA | NA | |||||||||||||
GLN | P:39 | P:177 | 94.0 | 0.522 | H | -60.8 | -42.3 | NA | NA | NA | |||||||||||||
GLN | T:39 | T:177 | 92.0 | 0.511 | H | -59.8 | -41.3 | NA | NA | NA | |||||||||||||
GLN | X:39 | X:177 | 95.0 | 0.528 | H | -60.4 | -42.3 | NA | NA | NA | |||||||||||||
GLN | BA:39 | b:177 | 92.0 | 0.511 | H | -60.6 | -42.0 | NA | NA | NA | |||||||||||||
GLN | FA:39 | f:177 | 95.0 | 0.528 | H | -60.1 | -42.2 | NA | NA | NA | |||||||||||||
5lob | 3 | P60881 | 100.0 | 1e-37 |
X-RAY |
2017-06-21 | GLN | E:70 | E:177 | 82.0 | 0.456 | H | -84.8 | -35.3 | 10.0 | 0.056 | 0.4 |
D:P60881:0.4 |
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GLN | G:70 | G:177 | 81.0 | 0.45 | H | -70.0 | -32.8 | 7.0 | 0.039 | 0.411 |
F:P60881:0.411 |
SO4 SO4 |
5.719 3.977 |
OE1 OE1 |
O4 O1 |
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1kil | 4 | P60880 | 100.0 | 1e-37 |
X-RAY |
2002-03-13 | GLN | D:39 | D:177 | 87.0 | 0.483 | H | -63.7 | -36.9 | 16.0 | 0.089 | 0.394 |
C:P60880:0.394 |
MG HOH |
5.002 2.925 |
OE1 OE1 |
MG O |
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1xtg | 2 | P60880 | 100.0 | 3e-35 |
X-RAY |
2004-12-21 | GLN | B:32 | B:177 | 179.0 | 0.994 | -131.9 | 166.9 | 129.0 | 0.717 | 0.277 |
A:33321098:0.278 |
HOH |
2.837 |
OE1 |
O |
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3zur | 1 | P10845,P60880 | 98.41 | 9e-34 |
X-RAY |
2011-12-07 | GLN | A:483 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
GLN | B:483 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p60880-f1 | 1 | P60880 | 95.63 | 1e-143 | GLN | A:177 | A:177 | 22.0 | 0.122 | H | -67.5 | -44.2 |