Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10286777 . G A CCDS13109.1:NM_003081.3:c.553Gct>Act_NP_003072.2:p.185A>T Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:188 H:185 34.0 0.296 H -62.9 -33.0 14.0 0.122 0.174 I:P63045:0.174
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:188 H:185 34.0 0.296 H -91.5 -43.3 7.0 0.061 0.235 I:P63045:0.235
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:188 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:188 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 ALA M:179 M:185 48.0 0.417 H -63.3 -39.2 0.0 0.0 0.417 K:P63045:0.417
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:169 M:185 35.0 0.304 H -52.4 -45.0 4.0 0.035 0.269 K:P63045:0.27
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:169 M:185 36.0 0.313 H -51.9 -49.4 4.0 0.035 0.278 K:P63045:0.278
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:169 M:185 37.0 0.322 H -52.1 -49.2 4.0 0.035 0.287 K:P63045:0.287
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 ALA D:66 D:185 51.0 0.443 H -59.0 -37.5 1.0 0.009 0.434 C:P60881:0.139
A:P63045:0.374
ALA H:66 H:185 50.0 0.435 H -59.8 -45.9 NA NA NA
ALA L:66 L:185 49.0 0.426 H -55.3 -52.8 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 ALA D:62 D:185 55.0 0.478 H -69.8 -18.9 2.0 0.017 0.461 C:P60881:0.139
A:P63045:0.374
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 ALA D:55 D:185 58.0 0.504 H -62.8 -48.0 5.0 0.043 0.461 A:P63045:0.296
C:P60880:0.235
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 ALA D:47 D:185 55.0 0.478 H -66.5 -38.1 4.0 0.035 0.443 C:P60881:0.113
A:P63045:0.374
 HOH
 2.846
 O
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ALA D:45 D:185 56.0 0.487 H -65.9 -41.1 4.0 0.035 0.452 A:P63025:0.391
C:P60881:0.122
ALA J:45 J:185 55.0 0.478 H -67.3 -42.9 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ALA D:45 D:185 53.0 0.461 H -66.9 -39.8 3.0 0.026 0.435 A:P63025:0.33
C:P60881:0.2
ALA J:45 J:185 55.0 0.478 H -67.3 -42.0 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 ALA D:45 D:185 51.0 0.443 H -68.0 -41.6 3.0 0.026 0.417 C:P60881:0.13
A:P63045:0.348
 HOH
 2.711
 O
 O
ALA H:45 H:185 52.0 0.452 H -66.9 -41.4 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 ALA D:49 D:185 58.0 0.504 H -79.0 -4.0 3.0 0.026 0.478 C:P60881:0.174
A:P63045:0.365
 SO4
 8.118
 N
 O4
ALA H:49 H:185 55.0 0.478 H -73.4 -16.8 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 ALA D:49 D:185 48.0 0.417 H -78.4 -38.2 6.0 0.052 0.365 A:P63045:0.278
C:P60881:0.113
ALA H:49 H:185 48.0 0.417 H -78.0 -39.0 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:46 D:185 54.0 0.47 H -62.6 -46.6 5.0 0.043 0.427 C:P60881:0.13
A:P63045:0.357
ALA J:46 J:185 53.0 0.461 H -64.0 -48.5 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:46 D:185 54.0 0.47 H -65.8 -44.0 5.0 0.043 0.427 C:P60881:0.148
A:P63045:0.339
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:46 D:185 56.0 0.487 H -68.6 -38.4 2.0 0.017 0.47 C:P60881:0.148
A:P63045:0.374
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ALA D:46 D:185 54.0 0.47 H -74.0 -35.9 13.0 0.113 0.357 C:P60881:0.165
A:P63045:0.27
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ALA D:46 D:185 58.0 0.504 H -65.0 -42.9 22.0 0.191 0.313 C:P60881:0.226
A:P63045:0.113
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 ALA J:46 D:185 55.0 0.478 H -68.7 -38.4 2.0 0.017 0.461 G:P63045:0.374
I:P60881:0.139
ALA N:46 H:185 54.0 0.47 H -68.7 -38.3 2.0 0.017 0.453 M:P60881:0.139
K:P63045:0.365
ALA R:46 L:185 56.0 0.487 H -68.7 -38.3 3.0 0.026 0.461 Q:P60881:0.148
O:P63045:0.374
ALA V:46 P:185 55.0 0.478 H -68.6 -38.4 2.0 0.017 0.461 S:P63045:0.374
U:P60881:0.139
ALA Z:46 T:185 54.0 0.47 H -68.6 -38.4 2.0 0.017 0.453 W:P63045:0.365
Y:P60881:0.139
ALA DA:46 X:185 55.0 0.478 H -68.7 -38.3 2.0 0.017 0.461 AA:P63045:0.365
CA:P60881:0.139
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 ALA D:50 D:184 51.0 0.443 H -57.4 -48.2 0.0 0.0 0.443 C:P13795:0.157
A:Q9Z152:0.409
 HOH
 4.064
 O
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 ALA E:64 E:185 50.0 0.435 H -74.6 -38.7 6.0 0.052 0.383 D:P60881:0.13
G:P60881:0.278
F:P60881:0.009
 HOH
 8.535
 N
 O
ALA G:64 G:185 53.0 0.461 H -61.4 -49.6 9.0 0.078 0.383 D:P60881:0.13
F:P60881:0.148
E:P60881:0.235
ALA L:64 L:185 27.0 0.235 H -60.1 -42.9 NA NA NA
ALA N:64 N:185 39.0 0.339 H -64.3 -42.3 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:47 D:185 56.0 0.487 H -66.7 -42.2 42.0 0.365 0.122 C:P60880:0.122
 HOH
 8.265
 N
 O
ALA H:47 H:185 55.0 0.478 H -52.4 -47.5 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:47 D:185 48.0 0.417 H -60.2 -41.2 37.0 0.322 0.095 C:P60880:0.096
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:47 D:185 26.0 0.226 H -62.2 -47.9 14.0 0.122 0.104 C:P60880:0.104
ALA H:47 H:185 42.0 0.365 H -62.9 -46.3 NA NA NA
ALA L:47 L:185 49.0 0.426 H -62.7 -46.6 NA NA NA
ALA P:47 P:185 56.0 0.487 H -63.3 -45.3 NA NA NA
ALA T:47 T:185 58.0 0.504 H -63.2 -45.9 NA NA NA
ALA X:47 X:185 31.0 0.27 H -62.8 -46.9 NA NA NA
ALA BA:47 b:185 49.0 0.426 H -62.8 -46.0 NA NA NA
ALA FA:47 f:185 56.0 0.487 H -62.7 -45.2 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 ALA E:78 E:185 47.0 0.409 H -85.6 -42.6 5.0 0.043 0.366 D:P60881:0.148
G:P60881:0.217
F:P60881:0.113
ALA G:78 G:185 50.0 0.435 H -74.6 -36.6 8.0 0.07 0.365 E:P60881:0.217
D:P60881:0.087
F:P60881:0.165
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 ALA D:47 D:185 54.0 0.47 H -65.4 -32.9 3.0 0.026 0.444 C:P60880:0.13
A:P63045:0.365
 HOH
 6.578
 C
 O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 ALA B:40 B:185 95.0 0.826 -60.4 102.0 89.0 0.774 0.052 A:33321098:0.052
 HOH
 8.537
 N
 O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 ALA A:491 NA:NA DO NA DO DO DO NA NA NA
ALA B:491 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 ALA A:185 A:185 35.0 0.304 H -64.5 -46.2