Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10286799 . T A CCDS13109.1:NM_003081.3:c.575aTt>aAt_NP_003072.2:p.192I>N Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:195 H:192 74.0 0.423 H -69.3 -38.4 11.0 0.063 0.36 H:P32851:0.08
I:P63045:0.303
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:195 H:192 73.0 0.417 H -65.3 -37.5 8.0 0.046 0.371 H:P32851:0.051
I:P63045:0.326
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:195 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:195 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 ILE M:186 M:192 80.0 0.457 H -81.8 -37.4 3.0 0.017 0.44 L:P32851:0.029
K:P63045:0.429
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:176 M:192 82.0 0.469 H -56.3 -30.5 1.0 0.006 0.463 L:P32851:0.103
K:P63045:0.406
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:176 M:192 75.0 0.429 H -71.1 -44.2 2.0 0.011 0.418 L:P32851:0.034
K:P63045:0.411
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:176 M:192 75.0 0.429 H -71.1 -44.2 1.0 0.006 0.423 L:P32851:0.034
K:P63045:0.417
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 ILE D:73 D:192 99.0 0.566 H -61.6 -58.3 0.0 0.0 0.566 B:P32851:0.154
C:P60881:0.269
A:P63045:0.377
ILE H:73 H:192 110.0 0.629 H -65.4 -43.8 NA NA NA
ILE L:73 L:192 108.0 0.617 H -64.7 -37.9 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 ILE D:69 D:192 87.0 0.497 H -68.1 -36.8 6.0 0.034 0.463 B:P32851:0.04
C:P60881:0.114
A:P63045:0.343
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 ILE D:62 D:192 117.0 0.669 H -64.0 -40.4 2.0 0.011 0.658 B:P32851:0.131
A:P63045:0.446
C:P60880:0.194
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 ILE D:54 D:192 109.0 0.623 H -69.0 -41.4 1.0 0.006 0.617 B:P32851:0.154
C:P60881:0.194
A:P63045:0.44
 HOH
 3.650
 CG2
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ILE D:52 D:192 115.0 0.657 H -65.8 -44.2 1.0 0.006 0.651 A:P63025:0.451
B:P32851:0.16
C:P60881:0.217
ILE J:52 J:192 113.0 0.646 H -73.4 -45.0 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ILE D:52 D:192 112.0 0.64 H -68.3 -42.7 0.0 0.0 0.64 A:P63025:0.446
B:P32851:0.143
C:P60881:0.211
ILE J:52 J:192 113.0 0.646 H -69.6 -42.2 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 ILE D:52 D:192 98.0 0.56 H -73.2 -37.7 1.0 0.006 0.554 B:P32851:0.137
C:P60881:0.206
A:P63045:0.377
 HOH
 2.516
 HG22
 O
ILE H:52 H:192 100.0 0.571 H -70.9 -35.9 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 ILE D:56 D:192 110.0 0.629 H -94.0 -41.4 1.0 0.006 0.623 B:P32851:0.143
C:P60881:0.2
A:P63045:0.423
 SO4
 9.057
 N
 O2
ILE H:56 H:192 109.0 0.623 H -89.5 -39.9 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 ILE D:56 D:192 106.0 0.606 H -79.0 -45.8 9.0 0.051 0.555 B:P32851:0.069
A:P63045:0.394
C:P60881:0.126
ILE H:56 H:192 106.0 0.606 H -78.8 -45.9 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:53 D:192 112.0 0.64 H -66.0 -45.0 1.0 0.006 0.634 B:P32851:0.143
C:P60881:0.194
A:P63045:0.457
ILE J:53 J:192 115.0 0.657 H -66.8 -45.7 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:53 D:192 117.0 0.669 H -66.3 -40.9 3.0 0.017 0.652 B:P32851:0.166
C:P60881:0.211
A:P63045:0.457
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:53 D:192 121.0 0.691 H -78.3 -28.2 5.0 0.029 0.662 B:P32851:0.16
C:P60881:0.177
A:P63045:0.48
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ILE D:53 D:192 117.0 0.669 H -79.9 -35.6 82.0 0.469 0.2 C:P60881:0.2
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ILE D:53 D:192 126.0 0.72 H -75.5 -37.5 102.0 0.583 0.137 C:P60881:0.137
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 ILE J:53 D:192 122.0 0.697 H -78.3 -28.2 8.0 0.046 0.651 G:P63045:0.474
H:P32851:0.16
I:P60881:0.171
ILE N:53 H:192 121.0 0.691 H -78.2 -28.2 7.0 0.04 0.651 L:P32851:0.149
M:P60881:0.171
K:P63045:0.463
ILE R:53 L:192 120.0 0.686 H -78.2 -28.3 6.0 0.034 0.652 Q:P60881:0.177
P:P32851:0.16
O:P63045:0.463
ILE V:53 P:192 121.0 0.691 H -78.3 -28.2 6.0 0.034 0.657 T:P32851:0.154
S:P63045:0.474
U:P60881:0.171
ILE Z:53 T:192 121.0 0.691 H -78.3 -28.2 6.0 0.034 0.657 W:P63045:0.48
Y:P60881:0.177
X:P32851:0.154
ILE DA:53 X:192 121.0 0.691 H -78.3 -28.2 6.0 0.034 0.657 AA:P63045:0.48
BA:P32851:0.16
CA:P60881:0.171
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 ILE D:57 D:191 110.0 0.629 H -63.1 -47.9 0.0 0.0 0.629 B:P32851:0.154
C:P13795:0.229
A:Q9Z152:0.434
 HOH
 4.805
 N
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 ILE E:71 E:192 101.0 0.577 H -72.6 -46.4 4.0 0.023 0.554 D:P60881:0.171
G:P60881:0.229
F:P60881:0.377
 HOH
 9.262
 N
 O
ILE G:71 G:192 99.0 0.566 H -69.8 -41.3 0.0 0.0 0.566 D:P60881:0.457
F:P60881:0.131
E:P60881:0.246
 HOH
 8.421
 O
 O
ILE L:71 L:192 95.0 0.543 H -70.9 -42.6 NA NA NA
ILE N:71 N:192 98.0 0.56 H -71.7 -44.9 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:54 D:192 99.0 0.566 H -59.2 -49.0 53.0 0.303 0.263 B:P32851:0.12
C:P60880:0.2
 HOH
 6.284
 C
 O
ILE H:54 H:192 101.0 0.577 H -63.3 -43.6 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:54 D:192 107.0 0.611 H -72.2 -25.6 71.0 0.406 0.205 B:P32851:0.08
C:P60880:0.12
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:54 D:192 107.0 0.611 H -70.6 -34.9 62.0 0.354 0.257 B:P32851:0.103
C:P60880:0.177
ILE H:54 H:192 111.0 0.634 H -71.0 -34.8 NA NA NA
ILE L:54 L:192 107.0 0.611 H -69.6 -34.9 NA NA NA
ILE P:54 P:192 111.0 0.634 H -70.2 -35.0 NA NA NA
ILE T:54 T:192 109.0 0.623 H -70.9 -34.0 NA NA NA
ILE X:54 X:192 105.0 0.6 H -70.8 -34.7 NA NA NA
ILE BA:54 b:192 110.0 0.629 H -69.5 -35.2 NA NA NA
ILE FA:54 f:192 107.0 0.611 H -69.3 -35.4 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 ILE E:85 E:192 88.0 0.503 H -86.5 -45.5 0.0 0.0 0.503 D:P60881:0.166
G:P60881:0.16
F:P60881:0.377
ILE G:85 G:192 97.0 0.554 H -74.5 -44.1 3.0 0.017 0.537 E:P60881:0.177
D:P60881:0.406
F:P60881:0.143
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 ILE D:54 D:192 112.0 0.64 H -71.6 -42.9 1.0 0.006 0.634 B:P32851:0.16
C:P60880:0.2
A:P63045:0.457
 HOH
 5.499
 N
 O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 ILE B:47 B:192 154.0 0.88 -122.2 135.0 54.0 0.309 0.571 A:33321098:0.571
 HOH
 2.958
 O
 O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 ILE A:498 NA:NA DO NA DO DO DO NA NA NA
ILE B:498 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 ILE A:192 A:192 76.0 0.434 H -60.1 -47.4