Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10286813 . C A CCDS13109.1:NM_003081.3:c.589Caa>Aaa_NP_003072.2:p.197Q>K Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:200 H:197 108.0 0.6 H -71.1 -32.7 58.0 0.322 0.278 K:P54921:0.272
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:200 H:197 116.0 0.644 H -67.5 -35.2 58.0 0.322 0.322 K:P54921:0.322
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:200 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 GLN G:200 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 GLN M:191 M:197 128.0 0.711 H -61.3 -47.9 68.0 0.378 0.333 G:P54921:0.333
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:181 M:197 123.0 0.683 H -75.6 -32.1 85.0 0.472 0.211 G:P54921:0.211
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:181 M:197 138.0 0.767 H -87.5 -20.0 100.0 0.556 0.211 G:P54921:0.211
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 GLN M:181 M:197 138.0 0.767 H -87.7 -19.8 92.0 0.511 0.256 G:P54921:0.256
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 GLN D:78 D:197 127.0 0.706 H -49.0 -58.2 127.0 0.706 0.0
GLN H:78 H:197 156.0 0.867 H -52.8 -65.6 NA NA NA
GLN L:78 L:197 128.0 0.711 H -71.4 -36.6 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 GLN D:74 D:197 116.0 0.644 H -68.5 -25.9 28.0 0.156 0.488 E:A5D7S0:0.489
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 GLN D:67 D:197 113.0 0.628 H -62.0 -46.7 113.0 0.628 0.0
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 GLN D:59 D:197 126.0 0.7 H -65.4 -46.3 126.0 0.7 0.0 HOH
 2.786
 O
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 GLN D:57 D:197 44.0 NA H -62.8 -52.7 44.0 NA NA HOH
 6.209
 CA
 O
GLN J:57 J:197 100.0 0.556 H -61.1 -50.5 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 GLN D:57 D:197 46.0 NA H -60.2 -49.7 46.0 NA NA
GLN J:57 J:197 103.0 0.572 H -59.5 -50.1 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 GLN D:57 D:197 129.0 0.717 H -59.2 -45.3 129.0 0.717 0.0 HOH
 2.056
 HE21
 O
GLN H:57 H:197 136.0 0.756 H -60.0 -45.7 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 GLN D:61 D:197 152.0 0.844 T -99.4 -5.8 152.0 0.844 0.0
GLN H:61 H:197 155.0 0.861 H -96.4 -14.4 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 GLN D:61 D:197 165.0 0.917 S -99.4 5.5 165.0 0.917 0.0
GLN H:61 H:197 164.0 0.911 T -99.4 5.7 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:58 D:197 43.0 NA H -60.9 -55.3 43.0 NA NA HOH
 6.183
 CA
 O
GLN J:58 J:197 100.0 0.556 H -59.9 -53.9 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:58 D:197 140.0 0.778 H -57.1 -48.0 140.0 0.778 0.0
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 GLN D:58 D:197 130.0 0.722 H -63.4 -45.2 130.0 0.722 0.0
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 GLN D:58 NA:NA DO NA DO DO DO NA NA NA
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 GLN D:58 NA:NA DO NA DO DO DO NA NA NA
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 GLN J:58 D:197 131.0 0.728 H -63.4 -45.2 131.0 0.728 0.0
GLN N:58 H:197 130.0 0.722 H -63.4 -45.2 130.0 0.722 0.0
GLN R:58 L:197 133.0 0.739 H -63.4 -45.3 133.0 0.739 0.0
GLN V:58 P:197 131.0 0.728 H -63.4 -45.3 131.0 0.728 0.0
GLN Z:58 T:197 130.0 0.722 H -63.3 -45.3 130.0 0.722 0.0
GLN DA:58 X:197 133.0 0.739 H -63.3 -45.2 133.0 0.739 0.0
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 GLN D:62 D:196 70.0 NA H -81.2 -33.9 70.0 NA NA HOH
 3.724
 O
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 GLN E:76 E:197 207.0 1.0 -67.7 360.0 207.0 1.0 0.0
GLN G:76 G:197 139.0 0.772 -109.1 74.5 139.0 0.772 0.0 HOH
 7.376
 N
 O
GLN L:76 L:197 95.0 0.528 H -69.7 -25.7 NA NA NA
GLN N:76 N:197 156.0 0.867 -96.7 76.3 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:59 D:197 117.0 0.65 H -69.7 -35.6 117.0 0.65 0.0 HOH
 2.494
 O
 O
GLN H:59 H:197 101.0 0.561 H -63.7 -42.3 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:59 D:197 129.0 0.717 H -63.6 -32.4 129.0 0.717 0.0
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 GLN D:59 D:197 162.0 0.9 H -59.5 -41.7 162.0 0.9 0.0
GLN H:59 H:197 155.0 0.861 H -59.0 -42.9 NA NA NA
GLN L:59 L:197 116.0 0.644 H -59.0 -43.4 NA NA NA
GLN P:59 P:197 101.0 0.561 H -60.3 -40.4 NA NA NA
GLN T:59 T:197 147.0 0.817 H -59.6 -42.2 NA NA NA
GLN X:59 X:197 141.0 0.783 H -62.8 -40.0 NA NA NA
GLN BA:59 b:197 164.0 0.911 H -59.8 -42.0 NA NA NA
GLN FA:59 f:197 145.0 0.806 H -59.8 -42.1 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 GLN E:90 E:197 162.0 0.9 -113.0 108.4 159.0 0.883 0.017 G:P60881:0.017
GLN G:90 G:197 218.0 1.0 57.5 360.0 212.0 1.0 0.0 C:P47709:0.033
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 GLN D:59 D:197 105.0 0.583 H -60.9 -63.7 87.0 0.483 0.1 E:P63041:0.083
A:P63045:0.017
 HOH
 2.985
 NE2
 O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 GLN B:52 B:197 150.0 0.833 -78.0 103.3 64.0 0.356 0.477 A:33321098:0.478
 ZN
HOH
 6.158
3.257
 C
OE1
 ZN
O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 GLN A:503 NA:NA DO NA DO DO DO NA NA NA
GLN B:503 NA:NA DO NA DO DO DO NA NA NA
3dda 2 P60880 100.0 1.0 X-RAY
 2008-09-16 GLN B:1 B:197 225.0 1.0 360.0 120.0 61.0 0.339 0.661 A:A5HZZ9:0.911
 ZN
HOH
 2.105
2.843
 N
N
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 GLN A:197 A:197 115.0 0.639 H -61.9 -42.3