Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 1592139 | . | G | A | CCDS46571.1:NM_001135844.2:c.297aaC>aaT_NP_001129316.1:p.99N>N | Homo sapiens signal regulatory protein beta 1 (SIRPB1), transcript variant 3, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2wng | 1 | P78324 | 96.25 | 0.0 |
X-RAY |
2009-07-21 | GLU | A:70 | A:70 | 128.0 | 0.674 | T | -87.9 | 16.6 | 128.0 | 0.674 | 0.0 | ||||||
4i2x | 3 | Q9P1W8 | 82.3 | 0.0 |
X-RAY |
2013-12-18 | ASN | E:70 | E:70 | 126.0 | 0.787 | T | -91.6 | -12.2 | 117.0 | 0.731 | 0.056 |
B:None:0.056 |
HOH |
4.389 |
O |
O |
|
ASN | F:70 | F:70 | 122.0 | 0.762 | T | -90.6 | 10.0 | NA | NA | NA | |||||||||||||
2jjv | 1 | Q5TFQ8 | 100.0 | 5e-83 |
X-RAY |
2008-08-05 | ASN | A:70 | A:70 | 74.0 | NA | T | 75.5 | 11.2 | 74.0 | NA | NA |
HOH |
8.984 |
O |
O |
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ASN | B:70 | B:70 | 122.0 | 0.762 | T | -118.1 | 23.4 | NA | NA | NA | |||||||||||||
4cmm | 1 | P78324 | 94.12 | 4e-78 |
X-RAY |
2014-02-26 | ASN | A:70 | A:70 | 125.0 | 0.781 | T | -88.5 | 1.2 | 125.0 | 0.781 | 0.0 |
HOH |
2.699 |
OD1 |
O |
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6nmr | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | ASN | C:70 | S:70 | 119.0 | 0.744 | T | 54.7 | 39.1 | 39.0 | 0.244 | 0.5 |
B:None:0.5 |
HOH |
2.185 |
ND2 |
O |
|
ASN | F:70 | E:70 | 116.0 | 0.725 | T | 55.3 | 32.2 | NA | NA | NA | |||||||||||||
ASN | I:70 | I:70 | 136.0 | 0.85 | T | 57.9 | 36.7 | NA | NA | NA | |||||||||||||
ASN | L:70 | M:70 | 113.0 | 0.706 | T | 54.4 | 39.3 | NA | NA | NA | |||||||||||||
6nms | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | ASN | C:70 | S:70 | 99.0 | 0.619 | T | -93.7 | 9.9 | 99.0 | 0.619 | 0.0 |
HOH |
6.490 |
N |
O |
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ASN | F:70 | C:70 | 129.0 | 0.806 | T | -94.5 | 13.0 | NA | NA | NA | |||||||||||||
6nmt | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | ASN | C:70 | C:70 | 136.0 | 0.85 | T | -93.5 | 4.4 | 136.0 | 0.85 | 0.0 |
HOH |
2.641 |
O |
O |
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6nmu | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | ASN | C:70 | S:70 | 114.0 | 0.713 | T | 121.2 | -27.0 | 114.0 | 0.713 | 0.0 |
HOH |
4.637 |
C |
O |
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ASN | F:70 | C:70 | 122.0 | 0.762 | T | -119.4 | 45.2 | NA | NA | NA | |||||||||||||
6nmv | 1 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | ASN | A:70 | S:70 | 101.0 | 0.631 | T | -96.2 | 44.1 | 101.0 | 0.631 | 0.0 | ||||||
6bit | 3 | P78324 | 94.02 | 1e-76 |
X-RAY |
2017-12-06 | ASN | C:70 | H:70 | 116.0 | 0.725 | T | -93.5 | 10.5 | 116.0 | 0.725 | 0.0 |
HOH |
4.020 |
O |
O |
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ASN | F:70 | G:70 | 95.0 | 0.594 | T | 64.2 | 31.7 | NA | NA | NA | |||||||||||||
2jju | 1 | O00241 | 89.92 | 2e-74 |
X-RAY |
2008-08-05 | ASN | A:70 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
ASN | B:70 | B:70 | 114.0 | 0.713 | T | 66.0 | 13.2 | NA | NA | NA | |||||||||||||
2jjs | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2008-08-05 | GLU | A:70 | A:70 | 135.0 | 0.711 | T | -81.9 | -9.0 | 123.0 | 0.647 | 0.064 |
C:Q08722:0.063 |
IOD HOH |
7.836 2.877 |
O O |
I O |
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GLU | B:70 | B:70 | 145.0 | 0.763 | T | -73.7 | -15.7 | NA | NA | NA | |||||||||||||
2jjt | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2008-08-05 | GLU | A:70 | A:70 | 147.0 | 0.774 | T | -71.5 | -17.6 | 130.0 | 0.684 | 0.09 |
C:Q08722:0.089 |
HOH |
4.424 |
C |
O |
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GLU | B:70 | B:70 | 83.0 | NA | T | -70.4 | -18.8 | NA | NA | NA | |||||||||||||
2uv3 | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2007-03-27 | GLU | A:70 | A:70 | 111.0 | 0.584 | T | -85.2 | -7.6 | 55.0 | 0.289 | 0.295 |
B:P78324:0.295 |
SO4 SO4 SO4 MES HOH |
8.291 4.299 4.269 6.871 2.488 |
OE1 OE1 OE2 O OE1 |
O2 O2 O4 C2 O |
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GLU | B:70 | B:70 | 108.0 | 0.568 | T | -92.7 | 3.6 | 48.0 | 0.253 | 0.315 |
A:P78324:0.316 |
MES HOH |
6.662 2.667 |
O O |
C6 O |
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7kpg | 3 | P78324 | 93.04 | 5e-74 |
X-RAY |
2020-12-16 | ASN | C:68 | S:70 | 115.0 | 0.719 | T | -82.4 | -16.6 | 78.0 | 0.487 | 0.232 |
B:None:0.175 A:None:0.056 |
HOH |
3.660 |
ND2 |
O |
|
2jjw | 1 | Q9P1W8 | 81.51 | 1e-68 |
X-RAY |
2008-08-05 | ASN | A:70 | A:70 | 102.0 | 0.637 | T | -100.6 | 24.3 | 102.0 | 0.637 | 0.0 |
HOH |
2.747 |
ND2 |
O |
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4kjy | 2 | ? | 81.3 | 2e-68 |
X-RAY |
2013-06-12 | GLU | B:74 | B:70 | 123.0 | 0.647 | T | -87.7 | -0.0 | 113.0 | 0.595 | 0.052 |
A:Q08722:0.053 |
HOH |
2.422 |
OE2 |
O |
|
GLU | D:74 | D:70 | 127.0 | 0.668 | T | -89.0 | 4.2 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-o00241-f1 | 1 | O00241 | 87.44 | 0.0 | ASN | A:99 | A:99 | 134.0 | 0.838 | T | -114.6 | 27.5 | |
af-p78324-f1 | 1 | P78324 | 96.73 | 0.0 | ASN | A:100 | A:100 | 126.0 | 0.787 | T | -111.0 | 26.7 |