Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 1592152 | . | A | C | CCDS46571.1:NM_001135844.2:c.284cTc>cGc_NP_001129316.1:p.95L>R | Homo sapiens signal regulatory protein beta 1 (SIRPB1), transcript variant 3, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2wng | 1 | P78324 | 96.25 | 0.0 |
X-RAY |
2009-07-21 | SER | A:66 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
4i2x | 3 | Q9P1W8 | 82.3 | 0.0 |
X-RAY |
2013-12-18 | LEU | E:66 | E:66 | 15.0 | 0.088 | T | -60.6 | -33.8 | 15.0 | 0.088 | 0.0 |
HOH |
2.731 |
N |
O |
||
LEU | F:66 | F:66 | 17.0 | 0.1 | T | -70.6 | -19.3 | NA | NA | NA | |||||||||||||
2jjv | 1 | Q5TFQ8 | 100.0 | 5e-83 |
X-RAY |
2008-08-05 | LEU | A:66 | A:66 | 34.0 | 0.2 | S | -78.1 | -28.0 | 34.0 | 0.2 | 0.0 |
HOH |
3.862 |
CD2 |
O |
||
LEU | B:66 | B:66 | 36.0 | 0.212 | T | -70.9 | -10.3 | NA | NA | NA | |||||||||||||
4cmm | 1 | P78324 | 94.12 | 4e-78 |
X-RAY |
2014-02-26 | LEU | A:66 | A:66 | 19.0 | 0.112 | T | -74.1 | -4.9 | 3.0 | 0.018 | 0.094 |
B:Q08722:0.094 |
HOH |
3.027 |
N |
O |
|
6nmr | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | LEU | C:66 | S:66 | 142.0 | 0.835 | T | -76.1 | 161.2 | 128.0 | 0.753 | 0.082 |
B:None:0.076 A:None:0.006 |
HOH |
3.050 |
CB |
O |
|
LEU | F:66 | E:66 | 136.0 | 0.8 | T | -52.3 | -10.5 | NA | NA | NA | |||||||||||||
LEU | I:66 | I:66 | 147.0 | 0.865 | S | -68.9 | 165.5 | NA | NA | NA | |||||||||||||
LEU | L:66 | M:66 | 161.0 | 0.947 | S | -101.6 | 121.6 | NA | NA | NA | |||||||||||||
6nms | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | LEU | C:66 | S:66 | 24.0 | 0.141 | T | -75.7 | -23.5 | 24.0 | 0.141 | 0.0 |
HOH |
3.850 |
CB |
O |
||
LEU | F:66 | C:66 | 21.0 | 0.124 | T | -75.1 | -24.9 | NA | NA | NA | |||||||||||||
6nmt | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | LEU | C:66 | C:66 | 24.0 | 0.141 | T | -74.2 | -14.7 | 24.0 | 0.141 | 0.0 |
HOH |
2.650 |
O |
O |
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6nmu | 3 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | LEU | C:66 | S:66 | 14.0 | 0.082 | S | -80.2 | -18.8 | 14.0 | 0.082 | 0.0 |
HOH |
3.663 |
O |
O |
||
LEU | F:66 | C:66 | 21.0 | 0.124 | S | -76.7 | -20.7 | NA | NA | NA | |||||||||||||
6nmv | 1 | P78324 | 93.28 | 6e-77 |
X-RAY |
2019-08-07 | LEU | A:66 | S:66 | 39.0 | 0.229 | S | -81.2 | -24.3 | 39.0 | 0.229 | 0.0 |
HOH |
6.491 |
CD1 |
O |
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6bit | 3 | P78324 | 94.02 | 1e-76 |
X-RAY |
2017-12-06 | LEU | C:66 | H:66 | 25.0 | 0.147 | T | -72.7 | -13.5 | 25.0 | 0.147 | 0.0 |
HOH |
3.471 |
CD1 |
O |
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LEU | F:66 | G:66 | 25.0 | 0.147 | T | -71.4 | -19.5 | NA | NA | NA | |||||||||||||
2jju | 1 | O00241 | 89.92 | 2e-74 |
X-RAY |
2008-08-05 | LEU | A:66 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LEU | B:66 | B:66 | 22.0 | 0.129 | T | -70.1 | -22.1 | NA | NA | NA | |||||||||||||
2jjs | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2008-08-05 | SER | A:66 | A:66 | 20.0 | 0.174 | T | -82.0 | 3.4 | 3.0 | 0.026 | 0.148 |
C:Q08722:0.148 |
HOH |
2.741 |
O |
O |
|
SER | B:66 | B:66 | 18.0 | 0.157 | T | -86.0 | 2.4 | NA | NA | NA | |||||||||||||
2jjt | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2008-08-05 | SER | A:66 | A:66 | 21.0 | 0.183 | T | -80.5 | -3.3 | 3.0 | 0.026 | 0.157 |
C:Q08722:0.157 |
HOH |
2.996 |
O |
O |
|
SER | B:66 | B:66 | 22.0 | 0.191 | T | -81.2 | -3.9 | NA | NA | NA | |||||||||||||
2uv3 | 1 | P78324 | 92.44 | 3e-74 |
X-RAY |
2007-03-27 | SER | A:66 | A:66 | 36.0 | 0.313 | S | -155.9 | 168.0 | 15.0 | 0.13 | 0.183 |
B:P78324:0.183 |
SO4 SO4 HOH |
3.366 6.880 2.678 |
CA OG OG |
O1 O4 O |
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SER | B:66 | B:66 | 50.0 | 0.435 | -64.1 | 134.4 | 19.0 | 0.165 | 0.27 |
A:P78324:0.27 |
SO4 HOH |
9.732 2.589 |
N O |
O2 O |
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7kpg | 3 | P78324 | 93.04 | 5e-74 |
X-RAY |
2020-12-16 | LEU | C:64 | S:66 | 32.0 | 0.188 | T | -72.8 | -7.1 | 23.0 | 0.135 | 0.053 |
A:None:0.053 |
HOH |
2.792 |
N |
O |
|
2jjw | 1 | Q9P1W8 | 81.51 | 1e-68 |
X-RAY |
2008-08-05 | LEU | A:66 | A:66 | 23.0 | 0.135 | T | -66.8 | -16.2 | 23.0 | 0.135 | 0.0 |
HOH |
2.649 |
O |
O |
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4kjy | 2 | ? | 81.3 | 2e-68 |
X-RAY |
2013-06-12 | THR | B:70 | B:66 | 23.0 | 0.164 | T | -79.6 | 1.1 | 6.0 | 0.043 | 0.121 |
A:Q08722:0.121 |
HOH |
2.966 |
O |
O |
|
THR | D:70 | D:66 | 27.0 | 0.193 | T | -81.8 | 0.4 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-o00241-f1 | 1 | O00241 | 87.44 | 0.0 | LEU | A:95 | A:95 | 63.0 | 0.371 | T | -62.0 | -19.3 | |
af-p78324-f1 | 1 | P78324 | 96.73 | 0.0 | LEU | A:96 | A:96 | 57.0 | 0.335 | T | -67.1 | -13.3 |