Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895796 . T A CCDS13022.1:NM_001040022.1:c.131tTg>tAg_NP_001035111.1:p.44L>* Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 SER A:14 A:14 65.0 0.565 E -116.8 121.5 65.0 0.565 0.0 HOH
 4.801
 OG
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 LEU E:14 E:14 51.0 0.3 E -95.1 137.8 46.0 0.271 0.029 A:None:0.029
 HOH
 2.914
 O
 O
LEU F:14 F:14 51.0 0.3 E -99.6 126.3 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 LEU A:14 A:14 112.0 0.659 E -108.3 126.8 112.0 0.659 0.0 HOH
 2.912
 N
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 LEU C:14 S:14 56.0 0.329 -151.2 177.1 56.0 0.329 0.0 HOH
 7.695
 O
 O
LEU F:14 E:14 142.0 0.835 -113.1 135.8 NA NA NA
LEU I:14 I:14 143.0 0.841 -111.1 128.3 NA NA NA
LEU L:14 M:14 122.0 0.718 E -114.6 138.0 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 LEU C:14 S:14 109.0 0.641 E -109.9 128.6 66.0 0.388 0.253 B:None:0.253
 HOH
 4.610
 O
 O
LEU F:14 C:14 89.0 0.524 E -120.0 141.6 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 LEU C:14 C:14 81.0 0.476 E -119.2 124.4 51.0 0.3 0.176 B:None:0.176
 HOH
 2.807
 N
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 LEU C:14 S:14 104.0 0.612 E -112.8 125.8 104.0 0.612 0.0 HOH
 2.539
 O
 O
LEU F:14 C:14 85.0 0.5 E -141.0 129.8 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 LEU A:14 S:14 85.0 0.5 E -108.4 106.9 85.0 0.5 0.0 HOH
 8.118
 CD2
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 LEU C:14 H:14 98.0 0.576 E -122.0 123.8 98.0 0.576 0.0 HOH
 2.661
 O
 O
LEU F:14 G:14 101.0 0.594 E -110.0 122.9 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 LEU C:12 S:14 103.0 0.606 E -115.6 129.8 103.0 0.606 0.0 HOH
 2.630
 N
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 SER A:14 A:14 65.0 0.565 E -123.2 122.6 65.0 0.565 0.0 HOH
 4.251
 O
 O
SER B:14 B:14 55.0 0.478 E -126.0 136.5 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 SER A:14 A:14 66.0 0.574 E -97.3 128.0 66.0 0.574 0.0 HOH
 2.728
 OG
 O
SER B:14 B:14 26.0 0.226 E -136.2 145.6 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:14 A:14 71.0 0.617 E -115.7 130.1 71.0 0.617 0.0 HOH
 3.004
 N
 O
SER B:14 B:14 72.0 0.626 E -109.7 130.9 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:14 A:14 92.0 0.8 E -126.1 119.5 92.0 0.8 0.0 HOH
 5.442
 O
 O
SER B:14 B:14 96.0 0.835 E -126.1 119.9 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 SER A:14 A:14 60.0 0.522 E -118.3 120.7 60.0 0.522 0.0 MES
SO4
HOH
 5.071
7.624
2.485
 N
N
OG
 O1S
O1
O
SER B:14 B:14 66.0 0.574 E -113.1 127.5 66.0 0.574 0.0 MES
SO4
HOH
 4.931
7.517
2.491
 N
N
OG
 O3S
O3
O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 LEU A:14 A:14 119.0 0.7 E -100.5 114.6 39.0 0.229 0.471 A:Q9P1W8:0.471
 HOH
 4.815
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 LEU A:44 A:44 95.0 0.559 E -117.9 125.1
af-o00241-f1 1 O00241 86.98 0.0 SER A:43 A:43 60.0 0.522 E -124.2 122.6