Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895813 . A C CCDS13022.1:NM_001040022.1:c.148Aca>Cca_NP_001035111.1:p.50T>P Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 SER A:20 A:20 59.0 0.513 -104.6 142.8 59.0 0.513 0.0 HOH
 6.905
 O
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 THR E:20 E:20 73.0 0.521 -89.3 144.7 73.0 0.521 0.0 HOH
 2.731
 OG1
 O
THR F:20 F:20 74.0 0.529 -98.9 124.5 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 THR A:20 A:20 76.0 0.543 -97.5 134.7 76.0 0.543 0.0 HOH
 2.732
 O
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:20 S:20 79.0 0.564 -107.6 125.5 79.0 0.564 0.0 HOH
 2.650
 OG1
 O
THR F:20 E:20 65.0 0.464 -114.9 124.7 NA NA NA
THR I:20 I:20 50.0 0.357 -107.5 127.3 NA NA NA
THR L:20 M:20 76.0 0.543 -109.1 124.6 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:20 S:20 72.0 0.514 -113.5 128.1 72.0 0.514 0.0 HOH
 5.238
 CG2
 O
THR F:20 C:20 73.0 0.521 -113.6 127.0 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:20 C:20 76.0 0.543 -98.7 132.2 76.0 0.543 0.0 HOH
 2.787
 O
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:20 S:20 79.0 0.564 -92.7 141.3 79.0 0.564 0.0 HOH
 8.533
 O
 O
THR F:20 C:20 69.0 0.493 -83.9 140.3 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR A:20 S:20 70.0 0.5 -93.2 142.6 70.0 0.5 0.0 HOH
 5.582
 N
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 THR C:20 H:20 72.0 0.514 -106.9 140.9 72.0 0.514 0.0 HOH
 2.786
 O
 O
THR F:20 G:20 78.0 0.557 -97.9 130.5 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 THR C:18 S:20 78.0 0.557 -92.6 124.8 78.0 0.557 0.0 SO4
HOH
 7.913
2.745
 CG2
O
 O2
O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 SER A:20 A:20 40.0 0.348 -95.9 149.1 40.0 0.348 0.0 HOH
 2.860
 OG
 O
SER B:20 B:20 40.0 0.348 -95.2 151.3 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 SER A:20 A:20 64.0 0.557 -91.6 154.3 64.0 0.557 0.0 HOH
 2.821
 O
 O
SER B:20 B:20 64.0 0.557 -82.8 155.1 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:20 A:20 73.0 0.635 -96.6 142.1 73.0 0.635 0.0 NAG
HOH
 3.251
2.719
 OG
O
 O7
O
SER B:20 B:20 71.0 0.617 -91.0 141.0 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:20 A:20 66.0 0.574 -89.9 149.9 66.0 0.574 0.0 HOH
 4.089
 O
 O
SER B:20 B:20 66.0 0.574 -90.9 150.1 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 SER A:20 A:20 69.0 0.6 -88.7 156.6 69.0 0.6 0.0 MES
SO4
HOH
 7.579
7.604
2.638
 O
OG
O
 O1S
O2
O
SER B:20 B:20 62.0 0.539 -97.4 145.9 62.0 0.539 0.0 SO4
MES
HOH
 9.704
7.696
2.398
 O
O
OG
 O3
O3S
O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 THR A:20 A:20 82.0 0.586 -98.2 126.2 62.0 0.443 0.143 A:Q9P1W8:0.143
 HOH
 2.801
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 THR A:50 A:50 79.0 0.564 -114.0 120.9
af-o00241-f1 1 O00241 86.98 0.0 SER A:49 A:49 66.0 0.574 -109.4 134.1