Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895820 . C A CCDS13022.1:NM_001040022.1:c.155aCt>aAt_NP_001035111.1:p.52T>N Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 ILE A:22 A:22 61.0 0.349 E -103.4 118.6 61.0 0.349 0.0 HOH
 2.713
 O
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 THR E:22 E:22 31.0 0.221 E -111.3 109.6 31.0 0.221 0.0 HOH
 2.604
 N
 O
THR F:22 F:22 35.0 0.25 E -116.1 113.2 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 THR A:22 A:22 52.0 0.371 E -112.8 117.6 52.0 0.371 0.0 HOH
 2.742
 OG1
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:22 S:22 50.0 0.357 E -110.1 118.2 50.0 0.357 0.0 HOH
 6.588
 CG2
 O
THR F:22 E:22 54.0 0.386 E -106.9 121.4 NA NA NA
THR I:22 I:22 44.0 0.314 E -111.8 123.1 NA NA NA
THR L:22 M:22 50.0 0.357 E -111.8 118.0 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:22 S:22 39.0 0.279 E -110.5 125.2 39.0 0.279 0.0 HOH
 6.286
 O
 O
THR F:22 C:22 53.0 0.379 E -110.2 122.9 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:22 C:22 32.0 0.229 E -109.6 122.4 32.0 0.229 0.0 HOH
 2.447
 OG1
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR C:22 S:22 56.0 0.4 E -103.6 119.0 56.0 0.4 0.0
THR F:22 C:22 54.0 0.386 E -93.3 119.3 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 THR A:22 S:22 25.0 0.179 E -102.8 123.0 25.0 0.179 0.0 HOH
 4.053
 O
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 THR C:22 H:22 45.0 0.321 E -100.3 112.2 45.0 0.321 0.0 HOH
 2.723
 OG1
 O
THR F:22 G:22 59.0 0.421 E -102.4 119.5 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 THR C:20 S:22 19.0 0.136 E -106.7 115.8 19.0 0.136 0.0 SO4
HOH
 3.990
2.690
 CG2
OG1
 O2
O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 THR A:22 A:22 50.0 0.357 E -107.4 116.2 50.0 0.357 0.0 HOH
 2.783
 O
 O
THR B:22 B:22 33.0 0.236 E -108.1 116.9 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 THR A:22 A:22 66.0 0.471 E -104.4 124.3 66.0 0.471 0.0 HOH
 2.716
 OG1
 O
THR B:22 B:22 65.0 0.464 E -104.8 127.5 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ILE A:22 A:22 66.0 0.377 E -111.2 119.3 66.0 0.377 0.0 NAG
HOH
 6.237
2.722
 CD1
O
 O3
O
ILE B:22 B:22 64.0 0.366 E -109.0 120.3 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ILE A:22 A:22 59.0 0.337 E -103.4 121.5 59.0 0.337 0.0 HOH
 2.909
 N
 O
ILE B:22 B:22 61.0 0.349 E -104.4 119.7 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 ILE A:22 A:22 75.0 0.429 E -103.2 123.8 39.0 0.223 0.206 B:P78324:0.206
 MES
HOH
 5.146
2.652
 O
O
 O1S
O
ILE B:22 B:22 70.0 0.4 E -95.3 121.8 44.0 0.251 0.149 A:P78324:0.149
 SO4
SO4
MES
SO4
HOH
 9.158
6.625
5.080
9.724
2.691
 CD1
CD1
O
O
O
 O2
O4
O3S
O3
O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 THR A:22 A:22 42.0 0.3 E -109.1 121.6 8.0 0.057 0.243 A:Q9P1W8:0.243
 HOH
 2.774
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 THR A:52 A:52 35.0 0.25 E -113.0 121.7
af-o00241-f1 1 O00241 86.98 0.0 THR A:51 A:51 56.0 0.4 E -99.1 122.1