Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895826 . G A CCDS13022.1:NM_001040022.1:c.161cGc>cAc_NP_001035111.1:p.54R>H Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 HIS A:24 A:24 71.0 0.364 -87.6 144.8 71.0 0.364 0.0 HOH
 3.108
 O
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 HIS E:24 E:24 70.0 0.359 -95.8 126.6 6.0 0.031 0.328 B:None:0.328
 HOH
 2.795
 O
 O
HIS F:24 F:24 77.0 0.395 -90.9 131.4 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ARG A:24 A:24 109.0 0.484 -89.3 137.7 109.0 0.484 0.0 HOH
 2.770
 O
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:24 S:24 113.0 0.502 -96.4 148.2 113.0 0.502 0.0 HOH
 3.549
 CB
 O
ARG F:24 E:24 87.0 0.387 -87.4 146.0 NA NA NA
ARG I:24 I:24 126.0 0.56 -92.9 151.4 NA NA NA
ARG L:24 M:24 107.0 0.476 -90.1 148.6 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:24 S:24 109.0 0.484 -87.5 141.7 109.0 0.484 0.0 HOH
 2.415
 O
 O
ARG F:24 C:24 110.0 0.489 -90.9 145.0 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:24 C:24 101.0 0.449 -89.3 141.1 83.0 0.369 0.08 A:None:0.08
 HOH
 2.750
 NH1
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:24 S:24 120.0 0.533 -99.4 136.0 120.0 0.533 0.0 HOH
 7.394
 O
 O
ARG F:24 C:24 119.0 0.529 -90.2 138.7 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG A:24 S:24 120.0 0.533 -78.0 138.4 120.0 0.533 0.0 HOH
 2.780
 N
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ARG C:24 H:24 111.0 0.493 -83.8 143.2 111.0 0.493 0.0 HOH
 2.655
 O
 O
ARG F:24 G:24 116.0 0.516 -78.7 139.2 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ARG C:22 S:24 107.0 0.476 -99.9 144.1 107.0 0.476 0.0 SO4
HOH
 3.204
2.830
 NH2
O
 O2
O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 HIS A:24 A:24 67.0 0.344 -93.4 139.1 67.0 0.344 0.0 HOH
 2.859
 O
 O
HIS B:24 B:24 73.0 0.374 -90.6 140.2 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 ARG A:24 A:24 118.0 0.524 -93.9 140.4 118.0 0.524 0.0 HOH
 2.759
 O
 O
ARG B:24 B:24 117.0 0.52 -91.0 144.3 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 HIS A:24 A:24 73.0 0.374 -88.8 140.2 73.0 0.374 0.0 HOH
 2.934
 N
 O
HIS B:24 B:24 74.0 0.379 -90.7 141.3 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 HIS A:24 A:24 67.0 0.344 -92.6 141.9 67.0 0.344 0.0 HOH
 2.736
 NE2
 O
HIS B:24 B:24 70.0 0.359 -89.5 141.0 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 HIS A:24 A:24 68.0 0.349 -88.9 140.7 13.0 0.067 0.282 B:P78324:0.282
 MES
SO4
HOH
 3.561
9.553
2.728
 CD2
CD2
O
 C6
O3
O
HIS B:24 B:24 66.0 0.338 -88.7 143.1 13.0 0.067 0.271 A:P78324:0.272
 SO4
MES
SO4
HOH
 7.894
3.615
9.579
2.671
 NE2
CD2
CD2
NE2
 O4
C2
O4
O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 HIS A:24 A:24 66.0 0.338 -91.6 139.1 24.0 0.123 0.215 A:Q9P1W8:0.215
 HOH
 2.669
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ARG A:54 A:54 121.0 0.538 -89.6 133.6
af-o00241-f1 1 O00241 86.98 0.0 ARG A:53 A:53 139.0 0.618 -85.6 132.2