Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 1895835 | . | C | A | CCDS13022.1:NM_001040022.1:c.170gCg>gAg_NP_001035111.1:p.57A>E | Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2wng | 1 | P78324 | 95.94 | 0.0 |
X-RAY |
2009-07-21 | VAL | A:27 | A:27 | 7.0 | 0.045 | E | -105.3 | 148.8 | 7.0 | 0.045 | 0.0 |
HOH |
9.241 |
CB |
O |
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4i2x | 3 | Q9P1W8 | 82.19 | 0.0 |
X-RAY |
2013-12-18 | VAL | E:27 | E:27 | 10.0 | 0.065 | E | -104.4 | 152.3 | 4.0 | 0.026 | 0.039 |
B:None:0.039 |
HOH |
4.484 |
CG2 |
O |
|
VAL | F:27 | F:27 | 11.0 | 0.071 | E | -126.7 | 146.0 | NA | NA | NA | |||||||||||||
4cmm | 1 | P78324 | 100.0 | 6e-82 |
X-RAY |
2014-02-26 | ALA | A:27 | A:27 | 5.0 | 0.043 | E | -101.1 | 143.3 | 5.0 | 0.043 | 0.0 |
HOH |
4.891 |
CB |
O |
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6nmr | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | ALA | C:27 | S:27 | 12.0 | 0.104 | E | -100.4 | 152.9 | 12.0 | 0.104 | 0.0 |
HOH |
7.085 |
C |
O |
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ALA | F:27 | E:27 | 10.0 | 0.087 | E | -99.3 | 144.4 | NA | NA | NA | |||||||||||||
ALA | I:27 | I:27 | 4.0 | 0.035 | E | -100.4 | 139.9 | NA | NA | NA | |||||||||||||
ALA | L:27 | M:27 | 8.0 | 0.07 | E | -99.6 | 140.3 | NA | NA | NA | |||||||||||||
6nms | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | ALA | C:27 | S:27 | 3.0 | 0.026 | E | -105.0 | 133.1 | 3.0 | 0.026 | 0.0 |
HOH |
7.783 |
CA |
O |
||
ALA | F:27 | C:27 | 1.0 | 0.009 | E | -105.6 | 135.6 | NA | NA | NA | |||||||||||||
6nmt | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | ALA | C:27 | C:27 | 3.0 | 0.026 | E | -100.4 | 138.6 | 3.0 | 0.026 | 0.0 |
HOH |
3.894 |
CB |
O |
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6nmu | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | ALA | C:27 | S:27 | 3.0 | 0.026 | E | -89.7 | 150.5 | 3.0 | 0.026 | 0.0 |
HOH |
7.029 |
CB |
O |
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ALA | F:27 | C:27 | 2.0 | 0.017 | E | -107.1 | 141.9 | NA | NA | NA | |||||||||||||
6nmv | 1 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | ALA | A:27 | S:27 | 8.0 | 0.07 | E | -94.6 | 125.1 | 8.0 | 0.07 | 0.0 | ||||||
6bit | 3 | P78324 | 100.0 | 2e-80 |
X-RAY |
2017-12-06 | ALA | C:27 | H:27 | 6.0 | 0.052 | E | -95.5 | 147.5 | 6.0 | 0.052 | 0.0 |
HOH |
3.962 |
CB |
O |
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ALA | F:27 | G:27 | 3.0 | 0.026 | E | -93.0 | 144.3 | NA | NA | NA | |||||||||||||
7kpg | 3 | P78324 | 99.13 | 7e-78 |
X-RAY |
2020-12-16 | ALA | C:25 | S:27 | 9.0 | 0.078 | E | -116.4 | 147.5 | 9.0 | 0.078 | 0.0 |
HOH |
3.949 |
CB |
O |
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2jjv | 1 | Q5TFQ8 | 94.12 | 1e-76 |
X-RAY |
2008-08-05 | VAL | A:27 | A:27 | 9.0 | 0.058 | E | -98.9 | 161.5 | 9.0 | 0.058 | 0.0 |
HOH |
6.942 |
O |
O |
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VAL | B:27 | B:27 | 4.0 | 0.026 | E | -105.6 | 119.6 | NA | NA | NA | |||||||||||||
2jju | 1 | O00241 | 89.92 | 5e-73 |
X-RAY |
2008-08-05 | MET | A:27 | A:27 | 5.0 | 0.027 | E | -103.3 | 149.9 | 5.0 | 0.027 | 0.0 |
HOH |
3.623 |
CG |
O |
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MET | B:27 | B:27 | 5.0 | 0.027 | E | -100.5 | 149.4 | NA | NA | NA | |||||||||||||
2jjs | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2008-08-05 | VAL | A:27 | A:27 | 9.0 | 0.058 | E | -116.6 | 153.7 | 7.0 | 0.045 | 0.013 |
C:Q08722:0.013 |
IOD HOH |
7.750 2.717 |
CG2 O |
I O |
|
VAL | B:27 | B:27 | 9.0 | 0.058 | E | -116.6 | 149.7 | NA | NA | NA | |||||||||||||
2jjt | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2008-08-05 | VAL | A:27 | A:27 | 6.0 | 0.039 | E | -113.4 | 145.5 | 4.0 | 0.026 | 0.013 |
C:Q08722:0.013 |
HOH |
7.446 |
CG2 |
O |
|
VAL | B:27 | B:27 | 9.0 | 0.058 | E | -115.7 | 144.7 | NA | NA | NA | |||||||||||||
2uv3 | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2007-03-27 | VAL | A:27 | A:27 | 8.0 | 0.052 | E | -115.3 | 150.0 | 2.0 | 0.013 | 0.039 |
B:P78324:0.039 |
MES HOH |
7.167 2.790 |
O O |
O1 O |
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VAL | B:27 | B:27 | 8.0 | 0.052 | E | -110.4 | 151.8 | 2.0 | 0.013 | 0.039 |
A:P78324:0.039 |
MES HOH |
7.349 3.509 |
O CG2 |
O1 O |
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2jjw | 1 | Q9P1W8 | 80.67 | 1e-66 |
X-RAY |
2008-08-05 | VAL | A:27 | A:27 | 6.0 | 0.039 | E | -102.4 | 145.0 | 6.0 | 0.039 | 0.0 |
HOH |
4.232 |
CG2 |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p78324-f1 | 1 | P78324 | 100.0 | 0.0 | ALA | A:57 | A:57 | 4.0 | 0.035 | E | -115.2 | 139.6 | |
af-o00241-f1 | 1 | O00241 | 86.98 | 0.0 | MET | A:56 | A:56 | 7.0 | 0.038 | E | -109.8 | 145.0 |