Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895880 . C A CCDS13022.1:NM_001040022.1:c.215gCt>gAt_NP_001035111.1:p.72A>D Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 ALA A:42 A:42 52.0 0.452 -125.6 179.5 52.0 0.452 0.0 HOH
 4.086
 CB
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 VAL E:42 E:42 100.0 0.645 S -105.5 177.6 100.0 0.645 0.0 HOH
 3.341
 CA
 O
VAL F:42 F:42 98.0 0.632 S -123.0 174.9 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ALA A:42 A:42 67.0 0.583 S -126.7 173.1 67.0 0.583 0.0 HOH
 3.554
 CA
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ALA C:42 S:42 72.0 0.626 S -108.9 -9.0 72.0 0.626 0.0
ALA F:42 E:42 108.0 0.939 S -107.2 -8.0 NA NA NA
ALA I:42 I:42 73.0 0.635 S -106.2 -13.1 NA NA NA
ALA L:42 M:42 65.0 0.565 S -107.2 -9.3 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ALA C:42 S:42 71.0 0.617 S -120.5 160.7 18.0 0.157 0.46 A:None:0.461
 HOH
 4.104
 CB
 O
ALA F:42 C:42 72.0 0.626 S -118.3 158.3 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ALA C:42 C:42 65.0 0.565 S -124.7 1.2 65.0 0.565 0.0 HOH
 2.538
 O
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ALA C:42 S:42 65.0 0.565 S -111.8 -32.3 65.0 0.565 0.0 HOH
 2.792
 O
 O
ALA F:42 C:42 73.0 0.635 S -108.5 -43.6 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ALA A:42 S:42 75.0 0.652 S -106.9 167.2 5.0 0.043 0.609 B:None:0.478
C:None:0.2
 HOH
 2.855
 N
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ALA C:42 H:42 68.0 0.591 -127.8 171.5 68.0 0.591 0.0 HOH
 2.691
 O
 O
ALA F:42 G:42 72.0 0.626 S -117.1 159.0 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ALA C:40 S:42 69.0 0.6 S -124.7 8.9 69.0 0.6 0.0 HOH
 3.386
 CA
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 ALA A:42 A:42 68.0 0.591 S -116.3 14.5 68.0 0.591 0.0 HOH
 2.736
 O
 O
ALA B:42 B:42 71.0 0.617 S -141.3 156.1 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 ALA A:42 A:42 64.0 0.557 S -127.1 3.5 64.0 0.557 0.0 HOH
 2.596
 O
 O
ALA B:42 B:42 63.0 0.548 S -126.8 7.0 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ALA A:42 A:42 66.0 0.574 -131.1 174.8 66.0 0.574 0.0 IOD
HOH
 5.945
3.536
 N
CA
 I
O
ALA B:42 B:42 63.0 0.548 S -134.5 171.0 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ALA A:42 A:42 62.0 0.539 S -122.2 -23.4 62.0 0.539 0.0 HOH
 3.340
 CA
 O
ALA B:42 B:42 70.0 0.609 -135.9 164.0 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 ALA A:42 A:42 73.0 0.635 S -100.6 -7.0 73.0 0.635 0.0 HOH
 2.923
 O
 O
ALA B:42 B:42 73.0 0.635 S -98.9 -16.6 73.0 0.635 0.0 HOH
 2.751
 O
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 VAL A:42 A:42 97.0 0.626 S -124.9 169.7 97.0 0.626 0.0 HOH
 3.224
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ALA A:72 A:72 70.0 0.609 S -119.9 162.4
af-o00241-f1 1 O00241 86.98 0.0 ALA A:71 A:71 68.0 0.591 S -121.9 162.9