Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 1895889 | . | G | A | CCDS13022.1:NM_001040022.1:c.224gGc>gAc_NP_001035111.1:p.75G>D | Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2wng | 1 | P78324 | 95.94 | 0.0 |
X-RAY |
2009-07-21 | ALA | A:45 | A:45 | 108.0 | 0.939 | T | 54.5 | 52.6 | 108.0 | 0.939 | 0.0 |
HOH |
9.646 |
O |
O |
||
4i2x | 3 | Q9P1W8 | 82.19 | 0.0 |
X-RAY |
2013-12-18 | GLY | E:45 | E:45 | 76.0 | 1.0 | T | -87.5 | 3.9 | 76.0 | 1.0 | 0.0 |
HOH |
7.623 |
N |
O |
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GLY | F:45 | F:45 | 74.0 | 0.987 | T | -83.0 | 10.1 | NA | NA | NA | |||||||||||||
4cmm | 1 | P78324 | 100.0 | 6e-82 |
X-RAY |
2014-02-26 | GLY | A:45 | A:45 | 65.0 | 0.867 | T | -96.4 | 18.9 | 65.0 | 0.867 | 0.0 |
HOH |
5.741 |
C |
O |
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6nmr | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | GLY | C:45 | S:45 | 83.0 | 1.0 | T | -98.4 | 48.3 | 83.0 | 1.0 | 0.0 |
HOH |
6.449 |
O |
O |
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GLY | F:45 | E:45 | 83.0 | 1.0 | S | 126.1 | 49.5 | NA | NA | NA | |||||||||||||
GLY | I:45 | I:45 | 68.0 | 0.907 | T | -72.6 | 56.6 | NA | NA | NA | |||||||||||||
GLY | L:45 | M:45 | 77.0 | 1.0 | T | -82.1 | 25.5 | NA | NA | NA | |||||||||||||
6nms | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | GLY | C:45 | S:45 | 76.0 | 1.0 | T | -88.5 | 30.6 | 76.0 | 1.0 | 0.0 |
HOH |
6.461 |
C |
O |
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GLY | F:45 | C:45 | 71.0 | 0.947 | T | -89.4 | 36.3 | NA | NA | NA | |||||||||||||
6nmt | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | GLY | C:45 | C:45 | 76.0 | 1.0 | T | -82.6 | 9.4 | 76.0 | 1.0 | 0.0 |
HOH |
6.616 |
C |
O |
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6nmu | 3 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | GLY | C:45 | S:45 | 63.0 | 0.84 | T | -82.5 | 5.3 | 43.0 | 0.573 | 0.267 |
B:None:0.267 |
HOH |
2.635 |
N |
O |
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GLY | F:45 | C:45 | 65.0 | 0.867 | T | -72.9 | -5.1 | NA | NA | NA | |||||||||||||
6nmv | 1 | P78324 | 99.16 | 7e-81 |
X-RAY |
2019-08-07 | GLY | A:45 | S:45 | 75.0 | 1.0 | T | -91.2 | 21.1 | 0.0 | 0.0 | 1.0 |
B:None:1.0 |
HOH |
6.336 |
O |
O |
|
6bit | 3 | P78324 | 100.0 | 2e-80 |
X-RAY |
2017-12-06 | GLY | C:45 | H:45 | 77.0 | 1.0 | T | -90.9 | 22.1 | 67.0 | 0.893 | 0.107 |
B:None:0.133 |
HOH |
3.792 |
C |
O |
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GLY | F:45 | G:45 | 80.0 | 1.0 | T | -88.8 | 12.6 | NA | NA | NA | |||||||||||||
7kpg | 3 | P78324 | 99.13 | 7e-78 |
X-RAY |
2020-12-16 | GLY | C:43 | S:45 | 75.0 | 1.0 | T | -86.0 | 7.0 | 75.0 | 1.0 | 0.0 |
HOH |
4.170 |
C |
O |
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2jjv | 1 | Q5TFQ8 | 94.12 | 1e-76 |
X-RAY |
2008-08-05 | GLY | A:45 | A:45 | 69.0 | 0.92 | T | -111.5 | 21.8 | 69.0 | 0.92 | 0.0 |
SO4 HOH |
5.763 3.967 |
O C |
O1 O |
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GLY | B:45 | B:45 | 80.0 | 1.0 | T | -88.2 | 1.4 | NA | NA | NA | |||||||||||||
2jju | 1 | O00241 | 89.92 | 5e-73 |
X-RAY |
2008-08-05 | GLY | A:45 | A:45 | 78.0 | 1.0 | T | -89.6 | 15.3 | 78.0 | 1.0 | 0.0 |
HOH |
2.766 |
O |
O |
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GLY | B:45 | B:45 | 80.0 | 1.0 | T | -88.6 | 15.4 | NA | NA | NA | |||||||||||||
2jjs | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2008-08-05 | ALA | A:45 | A:45 | 98.0 | 0.852 | T | -101.4 | 14.9 | 98.0 | 0.852 | 0.0 |
IOD HOH |
8.383 3.737 |
O C |
I O |
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ALA | B:45 | B:45 | 96.0 | 0.835 | T | -82.7 | -5.3 | NA | NA | NA | |||||||||||||
2jjt | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2008-08-05 | ALA | A:45 | A:45 | 101.0 | 0.878 | T | -89.1 | 12.2 | 101.0 | 0.878 | 0.0 |
HOH |
8.372 |
C |
O |
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ALA | B:45 | B:45 | 106.0 | 0.922 | T | -89.3 | 4.8 | NA | NA | NA | |||||||||||||
2uv3 | 1 | P78324 | 89.08 | 2e-69 |
X-RAY |
2007-03-27 | ALA | A:45 | A:45 | 99.0 | 0.861 | T | -102.4 | 24.5 | 99.0 | 0.861 | 0.0 |
HOH |
2.616 |
O |
O |
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ALA | B:45 | B:45 | 100.0 | 0.87 | T | -101.3 | 18.1 | 100.0 | 0.87 | 0.0 |
HOH |
3.977 |
C |
O |
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2jjw | 1 | Q9P1W8 | 80.67 | 1e-66 |
X-RAY |
2008-08-05 | GLY | A:45 | A:45 | 80.0 | 1.0 | T | -79.7 | 2.6 | 80.0 | 1.0 | 0.0 |
HOH |
6.162 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p78324-f1 | 1 | P78324 | 100.0 | 0.0 | GLY | A:75 | A:75 | 76.0 | 1.0 | T | -90.3 | 9.3 | |
af-o00241-f1 | 1 | O00241 | 86.98 | 0.0 | GLY | A:74 | A:74 | 80.0 | 1.0 | G | -92.3 | 7.5 |