Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895965 . C A CCDS13022.1:NM_001040022.1:c.300aaC>aaA_NP_001035111.1:p.100N>K Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 GLU A:70 A:70 128.0 0.674 T -87.9 16.6 128.0 0.674 0.0
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 ASN E:70 E:70 126.0 0.787 T -91.6 -12.2 117.0 0.731 0.056 B:None:0.056
 HOH
 4.389
 O
 O
ASN F:70 F:70 122.0 0.762 T -90.6 10.0 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ASN A:70 A:70 125.0 0.781 T -88.5 1.2 125.0 0.781 0.0 HOH
 2.699
 OD1
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ASN C:70 S:70 119.0 0.744 T 54.7 39.1 39.0 0.244 0.5 B:None:0.5
 HOH
 2.185
 ND2
 O
ASN F:70 E:70 116.0 0.725 T 55.3 32.2 NA NA NA
ASN I:70 I:70 136.0 0.85 T 57.9 36.7 NA NA NA
ASN L:70 M:70 113.0 0.706 T 54.4 39.3 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ASN C:70 S:70 99.0 0.619 T -93.7 9.9 99.0 0.619 0.0 HOH
 6.490
 N
 O
ASN F:70 C:70 129.0 0.806 T -94.5 13.0 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ASN C:70 C:70 136.0 0.85 T -93.5 4.4 136.0 0.85 0.0 HOH
 2.641
 O
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ASN C:70 S:70 114.0 0.713 T 121.2 -27.0 114.0 0.713 0.0 HOH
 4.637
 C
 O
ASN F:70 C:70 122.0 0.762 T -119.4 45.2 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ASN A:70 S:70 101.0 0.631 T -96.2 44.1 101.0 0.631 0.0
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ASN C:70 H:70 116.0 0.725 T -93.5 10.5 116.0 0.725 0.0 HOH
 4.020
 O
 O
ASN F:70 G:70 95.0 0.594 T 64.2 31.7 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ASN C:68 S:70 115.0 0.719 T -82.4 -16.6 78.0 0.487 0.232 B:None:0.175
A:None:0.056
 HOH
 3.660
 ND2
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 ASN A:70 A:70 74.0 NA T 75.5 11.2 74.0 NA NA HOH
 8.984
 O
 O
ASN B:70 B:70 122.0 0.762 T -118.1 23.4 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 ASN A:70 NA:NA DO NA DO DO DO NA NA NA
ASN B:70 B:70 114.0 0.713 T 66.0 13.2 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 GLU A:70 A:70 135.0 0.711 T -81.9 -9.0 123.0 0.647 0.064 C:Q08722:0.063
 IOD
HOH
 7.836
2.877
 O
O
 I
O
GLU B:70 B:70 145.0 0.763 T -73.7 -15.7 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 GLU A:70 A:70 147.0 0.774 T -71.5 -17.6 130.0 0.684 0.09 C:Q08722:0.089
 HOH
 4.424
 C
 O
GLU B:70 B:70 83.0 NA T -70.4 -18.8 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 GLU A:70 A:70 111.0 0.584 T -85.2 -7.6 55.0 0.289 0.295 B:P78324:0.295
 SO4
SO4
SO4
MES
HOH
 8.291
4.299
4.269
6.871
2.488
 OE1
OE1
OE2
O
OE1
 O2
O2
O4
C2
O
GLU B:70 B:70 108.0 0.568 T -92.7 3.6 48.0 0.253 0.315 A:P78324:0.316
 MES
HOH
 6.662
2.667
 O
O
 C6
O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 ASN A:70 A:70 102.0 0.637 T -100.6 24.3 102.0 0.637 0.0 HOH
 2.747
 ND2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ASN A:100 A:100 126.0 0.787 T -111.0 26.7
af-o00241-f1 1 O00241 86.98 0.0 ASN A:99 A:99 134.0 0.838 T -114.6 27.5