Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895984 . C A CCDS13022.1:NM_001040022.1:c.319Cgc>Agc_NP_001035111.1:p.107R>S Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 SER A:77 A:77 22.0 0.191 E -121.9 133.6 22.0 0.191 0.0 HOH
 8.338
 CA
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 ARG E:77 E:77 99.0 0.44 E -107.2 127.0 93.0 0.413 0.027 B:None:0.027
 HOH
 5.029
 NH2
 O
ARG F:77 F:77 103.0 0.458 E -121.3 126.9 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ARG A:77 A:77 99.0 0.44 E -123.5 136.3 99.0 0.44 0.0 HOH
 2.862
 O
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:77 S:77 91.0 0.404 E -130.0 124.6 91.0 0.404 0.0 HOH
 4.038
 CD
 O
ARG F:77 E:77 92.0 0.409 E -131.9 123.0 NA NA NA
ARG I:77 I:77 88.0 0.391 E -137.4 128.3 NA NA NA
ARG L:77 M:77 85.0 0.378 E -137.3 121.1 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:77 S:77 95.0 0.422 E -124.1 137.3 95.0 0.422 0.0 HOH
 2.879
 O
 O
ARG F:77 C:77 100.0 0.444 E -124.3 134.9 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:77 C:77 89.0 0.396 E -117.8 129.5 89.0 0.396 0.0 HOH
 2.921
 O
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:77 S:77 96.0 0.427 E -111.7 132.7 96.0 0.427 0.0 HOH
 7.510
 O
 O
ARG F:77 C:77 99.0 0.44 E -108.1 136.5 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG A:77 S:77 97.0 0.431 E -124.5 98.4 97.0 0.431 0.0 HOH
 9.464
 N
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ARG C:77 H:77 98.0 0.436 E -122.2 129.7 98.0 0.436 0.0 HOH
 2.484
 NH2
 O
ARG F:77 G:77 96.0 0.427 E -122.7 135.5 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ARG C:75 S:77 91.0 0.404 E -115.0 131.5 91.0 0.404 0.0 SO4
HOH
 2.409
3.288
 NH2
O
 O2
O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 ARG A:77 A:77 98.0 0.436 E -122.7 129.2 98.0 0.436 0.0 HOH
 2.751
 NH1
 O
ARG B:77 B:77 104.0 0.462 E -117.0 125.1 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 SER A:77 A:77 28.0 0.243 E -123.8 132.1 28.0 0.243 0.0 SO4
HOH
 8.454
2.597
 O
OG
 O1
O
SER B:77 B:77 27.0 0.235 E -114.5 131.7 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:77 A:77 32.0 0.278 E -112.2 135.6 32.0 0.278 0.0 NAG
HOH
 2.568
2.833
 OG
OG
 O4
O
SER B:77 B:77 32.0 0.278 E -106.4 136.3 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:77 A:77 26.0 0.226 E -118.7 129.3 26.0 0.226 0.0 HOH
 7.177
 OG
 O
SER B:77 B:77 18.0 0.157 E -119.0 123.7 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 SER A:77 A:77 24.0 0.209 E -115.9 136.2 24.0 0.209 0.0 SO4
HOH
 8.474
2.711
 O
OG
 O2
O
SER B:77 B:77 25.0 0.217 E -109.7 128.5 25.0 0.217 0.0 HOH
 2.681
 OG
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 ARG A:77 A:77 105.0 0.467 E -111.0 127.8 90.0 0.4 0.067 A:Q9P1W8:0.067
 HOH
 2.645
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ARG A:107 A:107 96.0 0.427 E -115.3 131.3
af-o00241-f1 1 O00241 86.98 0.0 SER A:106 A:106 22.0 0.191 E -115.4 125.5