Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895990 . G A CCDS13022.1:NM_001040022.1:c.325Ggt>Agt_NP_001035111.1:p.109G>S Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 SER A:79 A:79 46.0 0.4 -79.2 160.5 46.0 0.4 0.0 HOH
 8.645
 O
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 SER E:79 E:79 41.0 0.357 -89.0 156.1 41.0 0.357 0.0 HOH
 3.741
 CA
 O
SER F:79 F:79 42.0 0.365 -80.8 162.0 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 GLY A:79 A:79 17.0 0.227 -85.7 163.6 17.0 0.227 0.0 HOH
 3.346
 N
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:79 S:79 17.0 0.227 -84.0 165.0 17.0 0.227 0.0 HOH
 3.754
 CA
 O
GLY F:79 E:79 14.0 0.187 -87.3 167.4 NA NA NA
GLY I:79 I:79 22.0 0.293 S -28.8 -87.2 NA NA NA
GLY L:79 M:79 16.0 0.213 -84.5 172.6 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:79 S:79 19.0 0.253 -89.7 163.4 19.0 0.253 0.0 HOH
 3.479
 N
 O
GLY F:79 C:79 20.0 0.267 -89.0 162.6 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:79 C:79 20.0 0.267 -89.9 158.5 20.0 0.267 0.0 HOH
 3.372
 C
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:79 S:79 18.0 0.24 -73.9 149.8 18.0 0.24 0.0 HOH
 6.310
 O
 O
GLY F:79 C:79 16.0 0.213 -75.5 154.4 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY A:79 S:79 20.0 0.267 -93.3 159.0 20.0 0.267 0.0 HOH
 8.096
 CA
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 GLY C:79 H:79 22.0 0.293 -89.7 157.7 22.0 0.293 0.0 HOH
 3.788
 CA
 O
GLY F:79 G:79 15.0 0.2 -88.1 155.9 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 GLY C:77 S:79 22.0 0.293 -84.6 158.0 22.0 0.293 0.0 HOH
 3.606
 N
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 SER A:79 A:79 36.0 0.313 -85.5 155.0 36.0 0.313 0.0 HOH
 3.707
 CA
 O
SER B:79 B:79 55.0 0.478 S -82.5 147.2 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 SER A:79 A:79 55.0 0.478 -79.3 151.7 55.0 0.478 0.0 SO4
HOH
 2.926
3.118
 OG
OG
 O1
O
SER B:79 B:79 47.0 0.409 S -78.6 155.2 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:79 A:79 33.0 0.287 -83.3 155.3 33.0 0.287 0.0 NAG
HOH
 3.526
2.826
 CB
OG
 O3
O
SER B:79 B:79 34.0 0.296 -82.4 156.9 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 SER A:79 A:79 31.0 0.27 -99.5 161.2 31.0 0.27 0.0 HOH
 9.599
 N
 O
SER B:79 B:79 29.0 0.252 -99.9 161.5 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 SER A:79 A:79 45.0 0.391 S -88.3 155.9 45.0 0.391 0.0 SO4
HOH
 2.983
3.661
 OG
C
 O2
O
SER B:79 B:79 47.0 0.409 -89.9 157.8 47.0 0.409 0.0 HOH
 2.600
 OG
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 SER A:79 A:79 40.0 0.348 -89.1 160.8 40.0 0.348 0.0 HOH
 2.838
 OG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 GLY A:109 A:109 18.0 0.24 -86.9 159.0
af-o00241-f1 1 O00241 86.98 0.0 SER A:108 A:108 45.0 0.391 -90.1 156.2