Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1895996 . A C CCDS13022.1:NM_001040022.1:c.331Atc>Ctc_NP_001035111.1:p.111I>L Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 ILE A:81 A:81 1.0 0.006 -67.2 140.1 1.0 0.006 0.0 HOH
 7.759
 C
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 ILE E:81 E:81 1.0 0.006 -58.5 127.7 1.0 0.006 0.0 HOH
 4.966
 N
 O
ILE F:81 F:81 1.0 0.006 -52.3 136.9 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ILE A:81 A:81 0.0 0.0 -67.7 139.5 0.0 0.0 0.0 HOH
 4.748
 C
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ILE C:81 S:81 2.0 0.011 -75.3 143.0 2.0 0.011 0.0 HOH
 7.557
 N
 O
ILE F:81 E:81 22.0 NA -84.4 137.8 NA NA NA
ILE I:81 I:81 7.0 0.04 -67.0 145.6 NA NA NA
ILE L:81 M:81 5.0 0.029 -95.1 136.4 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ILE C:81 S:81 1.0 0.006 -69.2 129.1 1.0 0.006 0.0 HOH
 5.200
 O
 O
ILE F:81 C:81 2.0 0.011 -67.7 129.3 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ILE C:81 C:81 0.0 0.0 -69.1 135.5 0.0 0.0 0.0 HOH
 4.597
 N
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ILE C:81 S:81 0.0 0.0 -77.0 136.1 0.0 0.0 0.0 HOH
 5.317
 CD1
 O
ILE F:81 C:81 0.0 0.0 -80.9 133.7 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ILE A:81 S:81 1.0 0.006 -59.5 117.9 1.0 0.006 0.0 HOH
 7.870
 O
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ILE C:81 H:81 0.0 0.0 -71.1 135.1 0.0 0.0 0.0 HOH
 4.862
 N
 O
ILE F:81 G:81 0.0 0.0 -72.9 130.3 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ILE C:79 S:81 2.0 0.011 -67.9 145.0 2.0 0.011 0.0 HOH
 5.757
 CD1
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 ILE A:81 A:81 0.0 0.0 -65.4 137.9 0.0 0.0 0.0 HOH
 4.769
 C
 O
ILE B:81 B:81 0.0 0.0 -62.8 134.2 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 ILE A:81 A:81 1.0 0.006 -67.7 136.9 1.0 0.006 0.0 SO4
HOH
 5.693
5.031
 N
N
 O1
O
ILE B:81 B:81 1.0 0.006 -72.2 127.5 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ILE A:81 A:81 1.0 0.006 -62.2 133.6 1.0 0.006 0.0 NAG
HOH
 7.904
4.814
 N
N
 O7
O
ILE B:81 B:81 1.0 0.006 -63.3 136.5 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ILE A:81 A:81 1.0 0.006 -65.0 129.4 1.0 0.006 0.0 HOH
 7.629
 CG1
 O
ILE B:81 B:81 1.0 0.006 -65.9 129.0 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 ILE A:81 A:81 0.0 0.0 -66.5 136.2 0.0 0.0 0.0 SO4
HOH
 5.729
4.939
 N
N
 O2
O
ILE B:81 B:81 0.0 0.0 -66.6 135.4 0.0 0.0 0.0 HOH
 3.727
 O
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 ILE A:81 A:81 2.0 0.011 -63.2 135.0 2.0 0.011 0.0 HOH
 4.662
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ILE A:111 A:111 1.0 0.006 -62.0 136.6
af-o00241-f1 1 O00241 86.98 0.0 ILE A:110 A:110 1.0 0.006 -63.8 133.6