Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1896014 . G A CCDS13022.1:NM_001040022.1:c.349Ggc>Agc_NP_001035111.1:p.117G>S Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 GLY A:87 A:87 22.0 0.293 E 149.2 -178.3 22.0 0.293 0.0 HOH
 4.555
 N
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 GLY E:87 E:87 23.0 0.307 E 165.0 -175.5 23.0 0.307 0.0 HOH
 9.728
 O
 O
GLY F:87 F:87 24.0 0.32 E 154.4 -171.3 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 GLY A:87 A:87 17.0 0.227 E 148.5 -176.4 17.0 0.227 0.0 HOH
 3.397
 CA
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:87 S:87 24.0 0.32 E 159.6 -163.8 24.0 0.32 0.0
GLY F:87 E:87 25.0 0.333 S 162.2 -163.1 NA NA NA
GLY I:87 I:87 26.0 0.347 S 163.1 -166.0 NA NA NA
GLY L:87 M:87 26.0 0.347 E 160.9 -165.8 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:87 S:87 26.0 0.347 E 148.7 -175.2 20.0 0.267 0.08 B:None:0.067
A:None:0.013
 HOH
 3.382
 CA
 O
GLY F:87 C:87 30.0 0.4 E 145.0 -175.7 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:87 C:87 25.0 0.333 E 155.7 -172.7 25.0 0.333 0.0 HOH
 3.163
 C
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY C:87 S:87 17.0 0.227 E 145.7 -160.3 17.0 0.227 0.0 HOH
 3.658
 CA
 O
GLY F:87 C:87 9.0 0.12 E 135.6 -175.3 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 GLY A:87 S:87 18.0 0.24 E 150.2 175.6 0.0 0.0 0.24 B:None:0.24
 HOH
 4.239
 N
 O
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 GLY C:87 H:87 15.0 0.2 E 157.7 -173.0 15.0 0.2 0.0 HOH
 4.090
 N
 O
GLY F:87 G:87 23.0 0.307 E 154.8 -171.2 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 GLY C:85 S:87 19.0 0.253 E 139.4 -176.4 19.0 0.253 0.0 HOH
 6.081
 N
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 GLY A:87 A:87 18.0 0.24 E 153.8 -176.6 18.0 0.24 0.0 HOH
 3.417
 CA
 O
GLY B:87 B:87 27.0 0.36 E 155.6 -172.5 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 GLY A:87 A:87 23.0 0.307 E 160.1 -174.6 23.0 0.307 0.0 HOH
 3.483
 C
 O
GLY B:87 B:87 26.0 0.347 E 160.4 -175.7 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 GLY A:87 A:87 16.0 0.213 E 154.3 -178.4 16.0 0.213 0.0 IOD
HOH
 3.754
3.565
 CA
CA
 I
O
GLY B:87 B:87 14.0 0.187 E 159.3 -170.5 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 GLY A:87 A:87 17.0 0.227 E 159.6 -171.5 17.0 0.227 0.0
GLY B:87 B:87 18.0 0.24 E 156.2 -173.1 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 GLY A:87 A:87 26.0 0.347 E 156.2 169.4 26.0 0.347 0.0 HOH
 3.300
 CA
 O
GLY B:87 B:87 21.0 0.28 E 150.0 -176.0 21.0 0.28 0.0 HOH
 3.295
 C
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 GLY A:87 A:87 20.0 0.267 E 153.8 179.8 20.0 0.267 0.0 HOH
 3.543
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 GLY A:117 A:117 27.0 0.36 E 141.2 179.5
af-o00241-f1 1 O00241 86.98 0.0 GLY A:116 A:116 17.0 0.227 E 134.1 -177.8