Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 1896039 . G A CCDS13022.1:NM_001040022.1:c.374cGg>cAg_NP_001035111.1:p.125R>Q Homo sapiens signal regulatory protein alpha (SIRPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wng 1 P78324 95.94 0.0 X-RAY
 2009-07-21 ARG A:95 A:95 117.0 0.52 E -93.1 141.1 117.0 0.52 0.0 HOH
 8.923
 CG
 O
4i2x 3 Q9P1W8 82.19 0.0 X-RAY
 2013-12-18 ARG E:95 E:95 114.0 0.507 E -110.8 165.5 114.0 0.507 0.0 HOH
 6.948
 O
 O
ARG F:95 F:95 99.0 0.44 E -105.4 148.7 NA NA NA
4cmm 1 P78324 100.0 6e-82 X-RAY
 2014-02-26 ARG A:95 A:95 136.0 0.604 E -100.5 152.4 134.0 0.596 0.008 B:Q08722:0.009
 HOH
 4.135
 CA
 O
6nmr 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:95 S:95 139.0 0.618 E -96.1 139.0 90.0 0.4 0.218 B:None:0.218
 HOH
 2.968
 NH1
 O
ARG F:95 E:95 109.0 0.484 E -96.0 138.3 NA NA NA
ARG I:95 I:95 127.0 0.564 E -96.3 136.8 NA NA NA
ARG L:95 M:95 145.0 0.644 E -93.1 137.1 NA NA NA
6nms 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:95 S:95 99.0 0.44 E -121.2 150.0 99.0 0.44 0.0
ARG F:95 C:95 106.0 0.471 E -123.1 153.2 NA NA NA
6nmt 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:95 C:95 100.0 0.444 E -109.0 165.7 100.0 0.444 0.0 HOH
 3.249
 CD
 O
6nmu 3 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG C:95 S:95 100.0 0.444 E -118.8 163.0 100.0 0.444 0.0 HOH
 6.439
 O
 O
ARG F:95 C:95 107.0 0.476 E -99.4 163.3 NA NA NA
6nmv 1 P78324 99.16 7e-81 X-RAY
 2019-08-07 ARG A:95 S:95 91.0 0.404 E -106.9 172.0 91.0 0.404 0.0
6bit 3 P78324 100.0 2e-80 X-RAY
 2017-12-06 ARG C:95 H:95 101.0 0.449 E -115.8 165.3 101.0 0.449 0.0 HOH
 3.286
 NH1
 O
ARG F:95 G:95 100.0 0.444 E -120.4 160.9 NA NA NA
7kpg 3 P78324 99.13 7e-78 X-RAY
 2020-12-16 ARG C:93 S:95 104.0 0.462 E -97.8 161.7 104.0 0.462 0.0 HOH
 6.019
 O
 O
2jjv 1 Q5TFQ8 94.12 1e-76 X-RAY
 2008-08-05 ARG A:95 A:95 21.0 NA E -92.1 139.1 21.0 NA NA HOH
 7.386
 O
 O
ARG B:95 B:95 108.0 0.48 E -125.3 169.1 NA NA NA
2jju 1 O00241 89.92 5e-73 X-RAY
 2008-08-05 ARG A:95 A:95 104.0 0.462 E -99.5 146.9 104.0 0.462 0.0 CL
HOH
 6.902
3.278
 CB
NE
 CL
O
ARG B:95 B:95 118.0 0.524 E -96.9 127.8 NA NA NA
2jjs 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ARG A:95 A:95 130.0 0.578 E -105.9 149.0 130.0 0.578 0.0 IOD
IOD
HOH
 3.549
5.515
3.755
 CZ
NH2
CB
 I
I
O
ARG B:95 B:95 122.0 0.542 E -106.5 145.4 NA NA NA
2jjt 1 P78324 89.08 2e-69 X-RAY
 2008-08-05 ARG A:95 A:95 121.0 0.538 E -113.4 146.5 121.0 0.538 0.0 HOH
 7.476
 C
 O
ARG B:95 B:95 121.0 0.538 E -111.0 147.2 NA NA NA
2uv3 1 P78324 89.08 2e-69 X-RAY
 2007-03-27 ARG A:95 A:95 111.0 0.493 E -93.1 124.0 111.0 0.493 0.0 HOH
 3.559
 NH2
 O
ARG B:95 B:95 116.0 0.516 E -92.5 127.4 116.0 0.516 0.0 HOH
 6.197
 C
 O
2jjw 1 Q9P1W8 80.67 1e-66 X-RAY
 2008-08-05 ARG A:95 A:95 21.0 NA E -106.9 155.0 21.0 NA NA HOH
 7.369
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78324-f1 1 P78324 100.0 0.0 ARG A:125 A:125 113.0 0.502 E -93.2 136.5
af-o00241-f1 1 O00241 86.98 0.0 ARG A:124 A:124 118.0 0.524 E -87.1 136.1