Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 44751261 | . | G | A | CCDS13393.1:NM_001250.4:c.269cGg>cAg_NP_001241.1:p.90R>Q | Homo sapiens CD40 molecule, TNF receptor superfamily member 5 (CD40), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6fax | 3 | P25942 | 100.0 | 3e-126 |
X-RAY |
2018-02-07 | ARG | C:70 | R:90 | 115.0 | 0.511 | E | -147.1 | 171.4 | 115.0 | 0.511 | 0.0 |
HOH |
9.437 |
CD |
O |
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| 6pe8 | 3 | P25942 | 100.0 | 3e-126 |
X-RAY |
2019-08-14 | ARG | E:70 | T:90 | 117.0 | 0.52 | E | -119.6 | 172.7 | NA | NA | NA | ||||||
| ARG | F:70 | U:90 | 137.0 | 0.609 | E | -102.0 | 167.3 | 111.0 | 0.493 | 0.116 |
B:None:0.071 A:None:0.049 |
HOH |
6.806 |
CB |
O |
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| 6pe9 | 3 | P25942 | 100.0 | 3e-126 |
X-RAY |
2019-08-14 | ARG | G:70 | G:90 | 42.0 | NA | E | -99.8 | 173.2 | NA | NA | NA | ||||||
| ARG | I:70 | I:90 | 39.0 | NA | E | -111.1 | 157.1 | NA | NA | NA | |||||||||||||
| ARG | J:70 | J:90 | 52.0 | NA | E | -115.0 | 146.8 | NA | NA | NA | |||||||||||||
| ARG | N:70 | U:90 | 86.0 | 0.382 | E | -128.7 | 152.9 | NA | NA | NA | |||||||||||||
| ARG | O:70 | V:90 | 128.0 | 0.569 | E | -124.0 | 161.3 | NA | NA | NA | |||||||||||||
| 3qd6 | 2 | P25942 | 97.71 | 4e-124 |
X-RAY |
2011-02-02 | ARG | G:70 | R:90 | 93.0 | 0.413 | E | -156.2 | 147.4 | 93.0 | 0.413 | 0.0 | ||||||
| ARG | H:70 | S:90 | 91.0 | 0.404 | E | -155.2 | 150.9 | 91.0 | 0.404 | 0.0 | |||||||||||||
| ARG | I:70 | T:90 | 92.0 | 0.409 | E | -160.0 | 149.8 | NA | NA | NA | |||||||||||||
| ARG | J:70 | U:90 | 91.0 | 0.404 | E | -156.9 | 145.9 | NA | NA | NA | |||||||||||||
| 5dmi | 1 | P25942 | 98.83 | 8e-123 |
X-RAY |
2016-06-01 | ARG | A:68 | A:90 | 33.0 | NA | -97.8 | -173.6 | 33.0 | NA | NA | |||||||
| 5dmj | 1 | P25942 | 98.83 | 8e-123 |
X-RAY |
2016-06-01 | ARG | A:68 | A:90 | 34.0 | NA | E | -135.1 | 140.0 | 34.0 | NA | NA | ||||||
| ARG | C:68 | D:90 | 124.0 | 0.551 | E | -138.7 | 137.9 | NA | NA | NA | |||||||||||||
| ARG | E:68 | F:90 | 40.0 | NA | E | -141.1 | 145.9 | NA | NA | NA | |||||||||||||
| 5ihl | 1 | P25942 | 98.83 | 8e-123 |
X-RAY |
2016-06-01 | ARG | A:68 | A:90 | 60.0 | NA | E | -127.6 | 161.5 | 60.0 | NA | NA | ||||||
| ARG | C:68 | D:90 | 28.0 | NA | E | -119.4 | 161.7 | NA | NA | NA | |||||||||||||
| ARG | E:68 | F:90 | 48.0 | NA | E | -123.5 | 160.5 | NA | NA | NA | |||||||||||||
| ARG | G:68 | H:90 | 57.0 | NA | E | -122.1 | 159.9 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p25942-f1 | 1 | P25942 | 100.0 | 0.0 | ARG | A:90 | A:90 | 116.0 | 0.516 | E | -131.5 | 155.9 | |