Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 6759527 | . | G | A | CCDS13099.1:NM_001200.2:c.982Gaa>Aaa_NP_001191.1:p.328E>K | Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1es7 | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2000-10-07 | GLU | A:48 | A:46 | 100.0 | 0.526 | B | -75.3 | 156.6 | 100.0 | 0.526 | 0.0 |
HOH |
2.850 |
CB |
O |
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GLU | C:48 | C:546 | 101.0 | 0.532 | B | -75.3 | 156.9 | 101.0 | 0.532 | 0.0 |
HOH |
2.680 |
OE2 |
O |
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2qj9 | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | GLU | A:48 | B:46 | 87.0 | 0.458 | B | -66.6 | 146.0 | 87.0 | 0.458 | 0.0 |
HOH |
2.876 |
CB |
O |
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GLU | B:48 | A:46 | 61.0 | 0.321 | B | -69.5 | 146.1 | 61.0 | 0.321 | 0.0 |
HOH |
2.356 |
OE1 |
O |
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2qja | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | GLU | A:48 | A:46 | 72.0 | 0.379 | B | -68.9 | 151.4 | 72.0 | 0.379 | 0.0 |
HOH |
6.505 |
O |
O |
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GLU | B:48 | B:46 | 72.0 | 0.379 | B | -60.0 | 145.8 | 72.0 | 0.379 | 0.0 |
HOH |
7.269 |
OE1 |
O |
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2qjb | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | GLU | A:48 | A:46 | 96.0 | 0.505 | B | -73.3 | 152.1 | 96.0 | 0.505 | 0.0 |
HOH |
6.462 |
O |
O |
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GLU | B:48 | B:46 | 75.0 | 0.395 | B | -63.6 | 149.0 | 75.0 | 0.395 | 0.0 |
HOH |
2.944 |
OE2 |
O |
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1rew | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2004-05-04 | GLU | A:46 | A:46 | 88.0 | 0.463 | B | -68.5 | 150.2 | 88.0 | 0.463 | 0.0 |
HOH |
2.522 |
OE1 |
O |
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GLU | B:46 | B:46 | 92.0 | 0.484 | B | -70.8 | 149.2 | 92.0 | 0.484 | 0.0 |
HOH |
3.881 |
C |
O |
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2goo | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2006-05-09 | GLU | A:46 | A:46 | 101.0 | 0.532 | B | -66.2 | 146.9 | 101.0 | 0.532 | 0.0 |
HOH |
3.682 |
C |
O |
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GLU | D:46 | D:46 | 94.0 | 0.495 | B | -72.4 | 146.5 | 94.0 | 0.495 | 0.0 |
HOH |
2.763 |
OE1 |
O |
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2h62 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2007-04-10 | GLU | A:46 | A:46 | 95.0 | 0.5 | B | -73.6 | 157.8 | 95.0 | 0.5 | 0.0 |
HOH |
3.573 |
CA |
O |
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GLU | B:46 | B:46 | 93.0 | 0.489 | B | -70.6 | 142.1 | 93.0 | 0.489 | 0.0 |
HOH |
2.533 |
OE2 |
O |
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3bmp | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2000-03-12 | GLU | A:46 | A:46 | 97.0 | 0.511 | B | -59.9 | 147.6 | 97.0 | 0.511 | 0.0 |
HOH |
9.658 |
N |
O |
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4uhy | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | GLU | A:46 | A:328 | 66.0 | 0.347 | B | -75.9 | 152.7 | 66.0 | 0.347 | 0.0 | ||||||
GLU | B:46 | B:328 | 71.0 | 0.374 | B | -65.8 | 146.7 | 71.0 | 0.374 | 0.0 | |||||||||||||
4uhz | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | GLU | A:46 | A:328 | 73.0 | 0.384 | B | -63.8 | 142.7 | 73.0 | 0.384 | 0.0 |
SO4 SO4 SO4 |
6.927 5.132 5.685 |
O OE2 N |
O2 O2 O3 |
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4ui0 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | GLU | A:46 | A:328 | 83.0 | 0.437 | B | -68.9 | 142.4 | 83.0 | 0.437 | 0.0 |
HOH |
3.917 |
CA |
O |
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GLU | B:46 | B:328 | 80.0 | 0.421 | B | -62.2 | 144.1 | 80.0 | 0.421 | 0.0 |
HOH |
9.544 |
N |
O |
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4ui1 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | GLU | A:46 | A:328 | 89.0 | 0.468 | B | -63.3 | 151.1 | 89.0 | 0.468 | 0.0 |
HOH |
4.430 |
CA |
O |
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GLU | B:46 | B:328 | 84.0 | 0.442 | B | -63.2 | 153.7 | NA | NA | NA | |||||||||||||
4ui2 | 2 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | GLU | B:46 | B:328 | 80.0 | 0.421 | -77.5 | 161.3 | 80.0 | 0.421 | 0.0 | |||||||
2h64 | 1 | P12643 | 98.25 | 8e-81 |
X-RAY |
2007-04-10 | GLU | A:46 | A:46 | 85.0 | 0.447 | B | -72.3 | 148.5 | 85.0 | 0.447 | 0.0 |
HOH |
2.875 |
OE2 |
O |
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3bk3 | 1 | P12643 | 98.25 | 1e-80 |
X-RAY |
2008-05-27 | GLU | A:46 | A:46 | 71.0 | 0.374 | B | -78.1 | 151.6 | 71.0 | 0.374 | 0.0 |
HOH |
4.736 |
CA |
O |
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GLU | B:46 | B:46 | 41.0 | 0.216 | B | -81.4 | 139.2 | 41.0 | 0.216 | 0.0 |
HOH |
4.721 |
OE2 |
O |
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6omn | 1 | P12643 | 100.0 | 1e-77 |
X-RAY |
2019-05-08 | GLU | A:40 | E:46 | 122.0 | 0.642 | B | -74.1 | 154.0 | 122.0 | 0.642 | 0.0 |
NAG |
8.625 |
O |
C8 |
||
GLU | B:40 | F:46 | 81.0 | 0.426 | B | -80.3 | 147.0 | 81.0 | 0.426 | 0.0 |
NAG HOH |
8.514 7.196 |
O OE2 |
C8 O |
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GLU | C:40 | G:46 | 72.0 | 0.379 | B | -88.2 | 147.5 | NA | NA | NA | |||||||||||||
GLU | D:40 | H:46 | 80.0 | 0.421 | B | -74.9 | 145.7 | NA | NA | NA | |||||||||||||
1reu | 1 | P12643 | 99.03 | 2e-75 |
X-RAY |
2004-05-04 | GLU | A:35 | A:46 | 107.0 | 0.563 | B | -86.9 | 137.1 | 107.0 | 0.563 | 0.0 |
HOH |
5.680 |
N |
O |
||
4mid | 1 | ? | 81.42 | 2e-68 |
X-RAY |
2014-05-07 | GLU | A:47 | A:46 | 84.0 | 0.442 | B | -83.5 | 160.5 | 84.0 | 0.442 | 0.0 |
HOH |
4.152 |
CA |
O |
||
6oml | 1 | ? | 85.71 | 9e-65 |
X-RAY |
2019-05-15 | GLU | A:36 | X:46 | 91.0 | 0.479 | B | -83.8 | 146.3 | 91.0 | 0.479 | 0.0 |
HOH |
6.877 |
OE2 |
O |
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GLU | B:36 | Y:46 | 80.0 | 0.421 | B | -87.7 | 150.3 | 80.0 | 0.421 | 0.0 |
NAG HOH |
7.967 3.114 |
O CB |
C8 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p12643-f1 | 1 | P12643 | 100.0 | 0.0 | GLU | A:328 | A:328 | 98.0 | 0.516 | B | -88.2 | 150.1 |