Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759585 . C A CCDS13099.1:NM_001200.2:c.1040aCg>aAg_NP_001191.1:p.347T>K Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 THR A:67 A:65 2.0 0.014 H -61.4 -38.6 1.0 0.007 0.007 B:P36894:0.007
 HOH
 2.475
 OG1
 O
THR C:67 C:565 1.0 0.007 H -62.8 -37.8 1.0 0.007 0.0 HOH
 2.401
 OG1
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 THR A:67 B:65 6.0 0.043 H -60.4 -45.4 5.0 0.036 0.007 C:P36894:0.007
 HOH
 2.583
 O
 O
THR B:67 A:65 5.0 0.036 H -70.7 -32.4 3.0 0.021 0.015 D:P36894:0.014
 HOH
 2.646
 OG1
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 THR A:67 A:65 4.0 0.029 H -63.0 -41.3 3.0 0.021 0.008 C:P36894:0.007
 HOH
 2.718
 OG1
 O
THR B:67 B:65 5.0 0.036 H -61.1 -44.9 5.0 0.036 0.0 HOH
 2.661
 O
 O
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 THR A:67 A:65 2.0 0.014 H -65.2 -44.7 1.0 0.007 0.007 C:P36894:0.007
 HOH
 6.077
 N
 O
THR B:67 B:65 5.0 0.036 H -72.5 -35.2 4.0 0.029 0.007 D:P36894:0.007
 HOH
 2.744
 O
 O
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 THR A:65 A:65 5.0 0.036 H -58.4 -43.1 4.0 0.029 0.007 C:P36894:0.007
 HOH
 2.716
 OG1
 O
THR B:65 B:65 5.0 0.036 H -60.2 -44.0 4.0 0.029 0.007 D:P36894:0.007
 HOH
 2.725
 OG1
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 THR A:65 A:65 4.0 0.029 H -60.7 -42.2 3.0 0.021 0.008 B:P36894:0.007
 HOH
 2.565
 OG1
 O
THR D:65 D:65 6.0 0.043 H -55.9 -46.3 5.0 0.036 0.007 E:P36894:0.007
 HOH
 2.653
 OG1
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 THR A:65 A:65 2.0 0.014 H -65.7 -41.4 2.0 0.014 0.0 HOH
 2.752
 O
 O
THR B:65 B:65 3.0 0.021 H -63.2 -44.4 2.0 0.014 0.007 C:P36894:0.007
 HOH
 2.657
 O
 O
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 THR A:65 A:65 1.0 0.007 H -60.8 -46.9 1.0 0.007 0.0 MPD
HOH
 9.272
5.968
 CB
N
 O2
O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 THR A:65 A:347 8.0 0.057 H -64.9 -45.7 8.0 0.057 0.0
THR B:65 B:347 14.0 0.1 H -64.4 -45.7 13.0 0.093 0.007 C:Q96B86:0.007
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 THR A:65 A:347 16.0 0.114 H -73.3 -22.3 16.0 0.114 0.0 SO4
 7.914
 O
 O3
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 THR A:65 A:347 16.0 0.114 H -63.8 -41.0 16.0 0.114 0.0 HOH
 6.743
 OG1
 O
THR B:65 B:347 2.0 0.014 H -63.3 -41.7 2.0 0.014 0.0 HOH
 5.973
 N
 O
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 THR A:65 A:347 8.0 0.057 H -63.8 -39.1 8.0 0.057 0.0 CL
HOH
 5.934
2.869
 CG2
OG1
 CL
O
THR B:65 B:347 8.0 0.057 H -62.3 -40.1 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 THR B:65 B:347 14.0 0.1 H -65.9 -30.5 14.0 0.1 0.0
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 THR A:65 A:65 3.0 0.021 H -64.8 -38.5 2.0 0.014 0.007 B:P36894:0.007
 HOH
 2.645
 OG1
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 THR A:65 A:65 5.0 0.036 H -59.0 -47.2 5.0 0.036 0.0 HOH
 2.720
 OG1
 O
THR B:65 B:65 3.0 0.021 H -69.4 -47.8 3.0 0.021 0.0 HOH
 2.853
 OG1
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 THR A:59 E:65 3.0 0.021 H -53.1 -45.0 3.0 0.021 0.0
THR B:59 F:65 0.0 0.0 H -63.7 -34.2 0.0 0.0 0.0 HOH
 4.112
 CB
 O
THR C:59 G:65 4.0 0.029 H -64.8 -39.3 NA NA NA
THR D:59 H:65 3.0 0.021 H -65.9 -32.4 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 THR A:54 A:65 7.0 0.05 H -68.4 -34.1 7.0 0.05 0.0 HOH
 6.236
 N
 O
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 THR A:66 A:65 6.0 0.043 H -63.1 -43.1 6.0 0.043 0.0 HOH
 2.323
 O
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 THR A:55 X:65 19.0 0.136 H -67.8 -45.6 19.0 0.136 0.0 HOH
 8.394
 CG2
 O
THR B:55 Y:65 5.0 0.036 H -59.1 -48.4 5.0 0.036 0.0 HOH
 3.304
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 THR A:347 A:347 0.0 0.0 H -70.0 -35.0