Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759670 . C A CCDS13099.1:NM_001200.2:c.1125gaC>gaA_NP_001191.1:p.375D>E Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 ASP A:95 A:93 26.0 0.173 -83.4 167.7 26.0 0.173 0.0 HOH
 9.121
 CB
 O
ASP C:95 C:593 26.0 0.173 -84.2 167.8 26.0 0.173 0.0 HOH
 3.593
 CA
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ASP A:95 B:93 37.0 0.247 -108.5 -173.4 25.0 0.167 0.08 D:P36894:0.08
 HOH
 9.500
 CB
 O
ASP B:95 A:93 57.0 0.38 -97.8 150.1 57.0 0.38 0.0 HOH
 2.689
 OD1
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ASP A:95 A:93 52.0 0.347 -107.7 -174.4 46.0 0.307 0.04 D:P36894:0.04
ASP B:95 B:93 38.0 0.253 -94.6 -161.0 29.0 0.193 0.06 C:P36894:0.06
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ASP A:95 A:93 57.0 0.38 -59.8 149.5 54.0 0.36 0.02 D:P36894:0.02
 HOH
 7.579
 C
 O
ASP B:95 B:93 48.0 0.32 E -83.5 167.7 43.0 0.287 0.033 C:P36894:0.033
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 ASP A:93 A:93 59.0 0.393 -96.0 -170.1 59.0 0.393 0.0 HOH
 8.546
 CA
 O
ASP B:93 B:93 45.0 0.3 -88.4 168.1 45.0 0.3 0.0 HOH
 8.352
 O
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 ASP A:93 A:93 57.0 0.38 -78.5 -174.3 33.0 0.22 0.16 C:P27038:0.16
 HOH
 6.646
 OD2
 O
ASP D:93 D:93 53.0 0.353 -86.2 -174.3 46.0 0.307 0.046 F:P27038:0.047
 HOH
 2.422
 OD1
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 ASP A:93 A:93 27.0 0.18 -82.1 179.3 27.0 0.18 0.0 HOH
 6.048
 OD2
 O
ASP B:93 B:93 34.0 NA E -80.8 158.2 34.0 NA NA
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 ASP A:93 A:93 28.0 0.187 -66.5 -175.5 28.0 0.187 0.0 HOH
 3.516
 C
 O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ASP A:93 A:375 68.0 0.453 -91.4 168.2 55.0 0.367 0.086 C:Q96B86:0.087
ASP B:93 B:375 51.0 0.34 -86.7 -169.9 51.0 0.34 0.0
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ASP A:93 A:375 81.0 0.54 -103.2 -177.4 54.0 0.36 0.18 B:Q6NW40:0.18
 SO4
 8.019
 OD2
 O2
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ASP A:93 A:375 52.0 0.347 -89.1 179.9 38.0 0.253 0.094 C:Q6NW40:0.093
 HOH
 7.110
 N
 O
ASP B:93 B:375 56.0 0.373 -86.2 -161.2 56.0 0.373 0.0
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ASP A:93 A:375 81.0 0.54 -100.7 -162.9 81.0 0.54 0.0 HOH
 3.738
 O
 O
ASP B:93 B:375 36.0 0.24 -80.3 -170.7 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 ASP B:93 B:375 49.0 0.327 -84.7 -171.5 37.0 0.247 0.08 C:Q6NW40:0.08
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 ASP A:93 A:93 46.0 0.307 -77.1 -175.5 46.0 0.307 0.0 HOH
 3.357
 O
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 ASP A:93 A:93 39.0 0.26 -71.1 -178.8 39.0 0.26 0.0
ASP B:93 B:93 35.0 0.233 -80.3 -178.4 35.0 0.233 0.0 HOH
 3.037
 CB
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 ASP A:87 E:93 47.0 0.313 -83.9 178.3 47.0 0.313 0.0
ASP B:87 F:93 53.0 0.353 -73.8 175.9 53.0 0.353 0.0
ASP C:87 G:93 45.0 0.3 -97.7 178.8 NA NA NA
ASP D:87 H:93 39.0 0.26 -122.1 -173.2 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 ASP A:82 A:93 41.0 0.273 -83.1 -160.4 41.0 0.273 0.0
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 ASP A:94 A:93 53.0 0.353 -85.8 -169.2 53.0 0.353 0.0 HOH
 8.746
 O
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 ASP A:84 X:93 50.0 0.333 -64.9 172.5 50.0 0.333 0.0 HOH
 5.499
 C
 O
ASP B:84 Y:93 11.0 0.073 -63.2 170.7 11.0 0.073 0.0 HOH
 3.507
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 ASP A:375 A:375 11.0 0.073 -81.9 -179.7