Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10258334 . C A CCDS13109.1:NM_003081.3:c.74tCg>tAg_NP_003072.2:p.25S>* Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 SER G:28 H:25 68.0 0.591 H -54.3 -37.4 7.0 0.061 0.53 H:P32851:0.53
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 SER G:28 H:25 83.0 0.722 H -56.0 -41.8 4.0 0.035 0.687 H:P32851:0.687
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 SER G:28 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 SER G:28 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 SER M:19 M:25 74.0 0.643 H -68.2 -26.9 0.0 0.0 0.643 L:P32851:0.643
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 SER M:9 M:25 60.0 0.522 H -67.8 -31.5 0.0 0.0 0.522 L:P32851:0.522
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 SER M:9 M:25 58.0 0.504 H -69.6 -26.6 1.0 0.009 0.495 L:P32851:0.496
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 SER M:9 M:25 58.0 0.504 H -69.7 -26.4 1.0 0.009 0.495 L:P32851:0.496
6ip1 3 P60881 91.0 1e-59 EM
 2019-04-24 SER C:27 C:25 46.0 0.4 H -65.5 -26.9 6.0 0.052 0.348 D:P60881:0.078
B:P32851:0.27
1sfc 3 P60881 100.0 3e-51 X-RAY
 1998-10-28 SER C:25 C:25 76.0 0.661 H -58.4 -44.3 0.0 0.0 0.661 B:P32851:0.626
D:P60881:0.157
 HOH
 7.165
 CB
 O
SER G:25 G:25 76.0 0.661 H -60.5 -52.6 NA NA NA
SER K:25 K:25 70.0 0.609 H -90.9 -39.5 NA NA NA
1urq 3 P13795 97.47 4e-47 X-RAY
 2004-08-26 SER C:22 C:25 76.0 0.661 H -66.1 -42.4 4.0 0.035 0.626 B:P32851:0.513
D:P13795:0.13
 HOH
 2.710
 OG
 O
3hd7 3 P60881 97.47 4e-47 X-RAY
 2009-07-14 SER C:22 C:25 77.0 0.67 H -77.6 -42.6 8.0 0.07 0.6 B:P32851:0.522
D:P60881:0.165
SER G:22 G:25 75.0 0.652 H -76.7 -42.9 NA NA NA
3ipd 3 P60881 97.47 4e-47 X-RAY
 2009-09-01 SER C:22 C:25 76.0 0.661 H -85.5 -21.1 8.0 0.07 0.591 B:P32851:0.461
D:P60881:0.2
SER G:22 G:25 78.0 0.678 H -85.8 -21.1 NA NA NA
1n7s 3 P60881 100.0 5e-47 X-RAY
 2002-12-27 SER C:21 C:25 76.0 0.661 H -65.3 -43.0 3.0 0.026 0.635 B:P32851:0.565
D:P60881:0.148
 CA
CA
HOH
 9.392
8.715
2.692
 N
N
OG
 CA
CA
O
2n1t 3 P60880 100.0 5e-47 NMR
 2015-06-03 SER C:19 C:25 68.0 0.591 H -64.6 -40.0 4.0 0.035 0.556 B:P32851:0.452
D:P60880:0.13
5ccg 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 SER C:19 C:25 77.0 0.67 H -64.7 -42.2 4.0 0.035 0.635 B:P32851:0.574
D:P60881:0.13
SER I:19 I:25 73.0 0.635 H -64.0 -41.3 NA NA NA
5cch 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 SER C:19 C:25 76.0 0.661 H -52.7 -35.7 7.0 0.061 0.6 B:P32851:0.53
D:P60881:0.139
5cci 3 P60881 100.0 5e-47 X-RAY
 2015-08-12 SER C:19 C:25 67.0 0.583 H -61.4 -39.9 9.0 0.078 0.505 B:P32851:0.383
D:P60881:0.183
5w5c 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 SER C:19 C:25 76.0 0.661 H -69.6 -47.8 8.0 0.07 0.591 B:P32851:0.478
D:P60881:0.157
 GOL
HOH
 8.138
7.059
 N
N
 O2
O
5w5d 3 P60881 100.0 5e-47 X-RAY
 2017-08-23 SER C:19 C:25 75.0 0.652 H -66.6 -50.0 0.0 0.0 0.652 D:P60881:0.148
B:P32851:0.6
 HOH
 7.108
 N
 O
6mti 5 P60881 100.0 5e-47 EM
 2019-04-24 SER I:19 C:25 67.0 0.583 H -61.4 -40.0 10.0 0.087 0.496 J:P60881:0.183
H:P32851:0.383
SER M:19 G:25 65.0 0.565 H -61.4 -39.9 8.0 0.07 0.495 N:P60881:0.183
L:P32851:0.374
SER Q:19 K:25 64.0 0.557 H -61.4 -40.0 8.0 0.07 0.487 P:P32851:0.374
R:P60881:0.174
SER U:19 O:25 65.0 0.565 H -61.4 -39.9 8.0 0.07 0.495 V:P60881:0.183
T:P32851:0.374
SER Y:19 S:25 67.0 0.583 H -61.3 -40.0 8.0 0.07 0.513 X:P32851:0.383
Z:P60881:0.191
SER CA:19 W:25 67.0 0.583 H -61.4 -40.0 8.0 0.07 0.513 BA:P32851:0.391
DA:P60881:0.191
5low 2 P60881 100.0 3e-46 X-RAY
 2017-06-21 SER D:38 D:25 62.0 0.539 H -70.5 -46.1 2.0 0.017 0.522 G:P60881:0.426
F:P60881:0.165
E:P60881:0.139
 HOH
 5.979
 OG
 O
SER F:38 F:25 59.0 0.513 H -73.6 -25.6 3.0 0.026 0.487 D:P60881:0.243
G:P60881:0.104
E:P60881:0.339
SER K:38 K:25 66.0 0.574 H -65.9 -40.2 NA NA NA
SER M:38 M:25 53.0 0.461 H -74.2 -37.9 NA NA NA
5lob 2 P60881 100.0 4e-46 X-RAY
 2017-06-21 SER D:43 D:25 67.0 0.583 H -65.5 -28.6 0.0 0.0 0.583 F:P60881:0.191
G:P60881:0.461
E:P60881:0.113
SER F:43 F:25 57.0 0.496 H -80.0 -41.1 0.0 0.0 0.496 G:P60881:0.122
D:P60881:0.191
E:P60881:0.4
1jth 1 P60881 92.68 4e-46 X-RAY
 2001-11-28 SER A:25 A:25 75.0 0.652 H -57.6 -34.4 7.0 0.061 0.591 B:P32851:0.026
D:P32851:0.565
 HOH
 3.852
 O
 O
SER C:25 C:25 72.0 0.626 H -62.2 -45.5 1.0 0.009 0.617 B:P32851:0.487
D:P32851:0.209
 HOH
 4.908
 N
 O
3rk2 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 SER C:23 C:25 76.0 0.661 H -58.1 -38.5 0.0 0.0 0.661 D:P60880:0.139
B:P32851:0.609
 HOH
 2.852
 OG
 O
SER G:23 G:25 76.0 0.661 H -60.0 -38.6 NA NA NA
3rk3 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 SER C:23 C:25 77.0 0.67 H -66.0 -43.4 3.0 0.026 0.644 B:P32851:0.6
D:P60880:0.122
3rl0 3 P60880 100.0 4e-46 X-RAY
 2011-07-27 SER C:23 C:25 73.0 0.635 H -65.3 -41.7 6.0 0.052 0.583 D:P60880:0.157
B:P32851:0.443
SER G:23 G:25 75.0 0.652 H -64.8 -43.0 NA NA NA
SER K:23 K:25 74.0 0.643 H -64.7 -42.1 NA NA NA
SER O:23 O:25 73.0 0.635 H -64.1 -42.6 NA NA NA
SER S:23 S:25 73.0 0.635 H -65.2 -42.3 NA NA NA
SER W:23 W:25 72.0 0.626 H -65.5 -41.9 NA NA NA
SER AA:23 a:25 73.0 0.635 H -64.6 -42.3 NA NA NA
SER EA:23 e:25 75.0 0.652 H -65.0 -42.1 NA NA NA
5kj7 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 SER C:17 C:25 75.0 0.652 H -65.8 -40.1 4.0 0.035 0.617 B:P32851:0.565
D:P60881:0.113
SER I:17 I:25 75.0 0.652 H -65.7 -39.0 NA NA NA
5kj8 3 P60881 100.0 2e-45 X-RAY
 2016-10-19 SER C:17 C:25 74.0 0.643 H -68.4 -36.0 3.0 0.026 0.617 D:P60881:0.165
B:P32851:0.53
SER I:17 I:25 75.0 0.652 H -68.0 -36.5 NA NA NA
6wvw 3 P60881 98.65 1e-43 X-RAY
 2021-03-17 SER C:16 C:25 74.0 0.643 H -63.6 -42.6 0.0 0.0 0.643 D:P60881:0.13
B:P32851:0.609
 MPD
HOH
 8.776
2.875
 O
OG
 HO2
O
SER G:16 G:25 72.0 0.626 H -64.0 -44.6 NA NA NA
1kil 3 P60880 100.0 3e-42 X-RAY
 2002-03-13 SER C:17 C:25 72.0 0.626 H -71.6 -34.3 8.0 0.07 0.556 D:P60880:0.157
B:P32851:0.426
 HOH
 6.237
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 SER A:25 A:25 56.0 0.487 H -67.5 -39.9