Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10273815 . T A CCDS13110.1:NM_130811.2:c.170cTg>cAg_NP_570824.1:p.57L>Q Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 95.59 1e-141 EM
 2018-09-19 LEU G:60 H:57 39.0 0.229 H -65.1 -24.2 19.0 0.112 0.117 H:P32851:0.1
I:P63045:0.018
6mdn 2 P60881 95.59 1e-141 EM
 2018-09-19 LEU G:60 H:57 34.0 0.2 H -57.4 -24.3 28.0 0.165 0.035 H:P32851:0.018
I:P63045:0.012
6mdo 2 P60881 95.59 1e-141 EM
 2018-09-19 LEU G:60 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 95.59 1e-141 EM
 2018-09-19 LEU G:60 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 96.97 1e-140 EM
 2015-01-28 LEU M:51 M:57 36.0 0.212 H -99.3 -24.8 3.0 0.018 0.194 L:P32851:0.124
K:P63045:0.082
3j96 5 ? 96.81 2e-133 EM
 2015-01-28 LEU M:41 M:57 32.0 0.188 H -86.5 -36.7 3.0 0.018 0.17 L:P32851:0.165
K:P63045:0.041
3j98 5 ? 96.81 2e-133 EM
 2015-01-28 LEU M:41 M:57 39.0 0.229 H -55.9 -25.6 4.0 0.024 0.205 L:P32851:0.147
K:P63045:0.059
3j99 5 ? 96.81 2e-133 EM
 2015-01-28 LEU M:41 M:57 40.0 0.235 H -55.9 -25.6 4.0 0.024 0.211 L:P32851:0.153
K:P63045:0.059
6ip1 3 P60881 100.0 1e-66 EM
 2019-04-24 LEU C:59 C:57 111.0 0.653 H -75.8 -16.6 1.0 0.006 0.647 D:P60881:0.535
B:P32851:0.082
A:P63045:0.188
1jth 1 P60881 100.0 1e-49 X-RAY
 2001-11-28 LEU A:57 A:57 108.0 0.635 H -70.0 -28.8 2.0 0.012 0.623 B:P32851:0.471
D:P32851:0.141
C:P60881:0.106
 HOH
 3.944
 CD1
 O
LEU C:57 C:57 104.0 0.612 H -64.5 -31.2 0.0 0.0 0.612 B:P32851:0.124
D:P32851:0.465
A:P60881:0.112
 HOH
 3.687
 CD1
 O
1sfc 3 P60881 92.77 9e-47 X-RAY
 1998-10-28 LEU C:57 C:57 114.0 0.671 H -58.8 -41.8 0.0 0.0 0.671 B:P32851:0.194
D:P60881:0.447
A:P63045:0.306
 SR
HOH
 7.095
5.937
 CB
CD1
 SR
O
LEU G:57 G:57 118.0 0.694 H -63.0 -35.0 NA NA NA
LEU K:57 K:57 115.0 0.676 H -65.2 -41.6 NA NA NA
1urq 3 P13795 89.87 1e-42 X-RAY
 2004-08-26 LEU C:54 C:57 119.0 0.7 H -65.9 -36.5 0.0 0.0 0.7 B:P32851:0.188
D:P13795:0.482
A:Q9Z152:0.265
 HOH
 4.145
 CB
 O
3hd7 3 P60881 89.87 1e-42 X-RAY
 2009-07-14 LEU C:54 C:57 118.0 0.694 H -62.4 -33.0 6.0 0.035 0.659 B:P32851:0.135
D:P60881:0.5
A:P63045:0.206
LEU G:54 G:57 113.0 0.665 H -67.4 -33.6 NA NA NA
3ipd 3 P60881 89.87 1e-42 X-RAY
 2009-09-01 LEU C:54 C:57 111.0 0.653 H -70.1 -14.2 14.0 0.082 0.571 B:P32851:0.135
A:P63045:0.182
D:P60881:0.424
LEU G:54 G:57 111.0 0.653 H -70.6 -13.7 NA NA NA
1n7s 3 P60881 92.21 2e-42 X-RAY
 2002-12-27 LEU C:53 C:57 115.0 0.676 H -62.4 -36.3 0.0 0.0 0.676 A:P63045:0.265
B:P32851:0.182
D:P60881:0.465
 HOH
 4.467
 CB
 O
2n1t 3 P60880 92.21 2e-42 NMR
 2015-06-03 LEU C:51 C:57 120.0 0.706 H -62.5 -38.9 8.0 0.047 0.659 A:P63045:0.106
B:P32851:0.118
D:P60880:0.488
5ccg 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 LEU C:51 C:57 120.0 0.706 H -65.5 -36.7 2.0 0.012 0.694 B:P32851:0.159
D:P60881:0.5
A:P63045:0.276
 CA
CA
 6.246
6.580
 CB
O
 CA
CA
LEU I:51 I:57 113.0 0.665 H -65.4 -35.0 NA NA NA
5cch 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 LEU C:51 C:57 119.0 0.7 H -61.9 -38.1 0.0 0.0 0.7 B:P32851:0.194
D:P60881:0.488
A:P63045:0.259
5cci 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 LEU C:51 C:57 116.0 0.682 H -63.0 -37.9 2.0 0.012 0.67 B:P32851:0.141
D:P60881:0.471
A:P63045:0.259
5w5c 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 LEU C:51 C:57 114.0 0.671 H -63.3 -34.5 4.0 0.024 0.647 B:P32851:0.165
A:P63045:0.212
D:P60881:0.471
 MG
HOH
 6.439
4.113
 CB
CB
 MG
O
5w5d 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 LEU C:51 C:57 114.0 0.671 H -68.0 -40.4 4.0 0.024 0.647 D:P60881:0.482
B:P32851:0.153
A:P63045:0.212
 MG
HOH
 7.059
4.692
 CB
CB
 MG
O
6mti 5 P60881 92.21 2e-42 EM
 2019-04-24 LEU I:51 C:57 117.0 0.688 H -62.9 -38.0 2.0 0.012 0.676 J:P60881:0.471
G:P63045:0.259
H:P32851:0.147
LEU M:51 G:57 116.0 0.682 H -63.0 -37.8 2.0 0.012 0.67 N:P60881:0.471
K:P63045:0.259
L:P32851:0.141
LEU Q:51 K:57 118.0 0.694 H -63.0 -37.9 2.0 0.012 0.682 P:P32851:0.147
R:P60881:0.488
O:P63045:0.259
LEU U:51 O:57 117.0 0.688 H -63.0 -37.8 2.0 0.012 0.676 V:P60881:0.476
T:P32851:0.147
S:P63045:0.265
LEU Y:51 S:57 118.0 0.694 H -62.9 -37.9 2.0 0.012 0.682 X:P32851:0.153
W:P63045:0.259
Z:P60881:0.488
LEU CA:51 W:57 118.0 0.694 H -63.0 -37.8 2.0 0.012 0.682 BA:P32851:0.147
AA:P63045:0.253
DA:P60881:0.476
5low 2 P60881 92.11 8e-42 X-RAY
 2017-06-21 LEU D:70 D:57 98.0 0.576 H -68.3 -31.1 3.0 0.018 0.558 G:P60881:0.106
F:P60881:0.082
E:P60881:0.424
 HOH
 5.560
 O
 O
LEU F:70 F:57 89.0 0.524 H -68.1 -21.5 1.0 0.006 0.518 D:P60881:0.082
G:P60881:0.406
E:P60881:0.106
 HOH
 5.749
 N
 O
LEU K:70 K:57 101.0 0.594 H -59.8 -36.9 NA NA NA
LEU M:70 M:57 97.0 0.571 H -61.9 -32.9 NA NA NA
5lob 2 P60881 92.11 9e-42 X-RAY
 2017-06-21 LEU D:75 D:57 103.0 0.606 H -65.3 -31.9 1.0 0.006 0.6 F:P60881:0.088
G:P60881:0.094
E:P60881:0.459
 SO4
 9.377
 N
 O4
LEU F:75 F:57 101.0 0.594 H -68.4 -28.6 1.0 0.006 0.588 G:P60881:0.459
D:P60881:0.088
E:P60881:0.106
 SO4
SO4
 6.647
6.987
 N
CB
 O1
O1
3rk2 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 LEU C:55 C:57 117.0 0.688 H -65.1 -34.1 5.0 0.029 0.659 D:P60880:0.482
B:P32851:0.165
A:P63027:0.2
 HOH
 7.549
 O
 O
LEU G:55 G:57 118.0 0.694 H -66.7 -33.8 NA NA NA
3rk3 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 LEU C:55 C:57 113.0 0.665 H -58.1 -36.8 9.0 0.053 0.612 B:P32851:0.141
A:P63027:0.106
D:P60880:0.459
3rl0 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 LEU C:55 C:57 116.0 0.682 H -61.8 -36.4 7.0 0.041 0.641 D:P60880:0.465
A:P63027:0.1
B:P32851:0.176
LEU G:55 G:57 112.0 0.659 H -61.2 -36.4 NA NA NA
LEU K:55 K:57 113.0 0.665 H -61.8 -36.9 NA NA NA
LEU O:55 O:57 113.0 0.665 H -62.3 -36.4 NA NA NA
LEU S:55 S:57 113.0 0.665 H -61.2 -36.6 NA NA NA
LEU W:55 W:57 111.0 0.653 H -61.6 -36.3 NA NA NA
LEU AA:55 a:57 113.0 0.665 H -62.1 -36.7 NA NA NA
LEU EA:55 e:57 112.0 0.659 H -62.4 -36.5 NA NA NA
5kj7 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 LEU C:49 C:57 121.0 0.712 H -65.5 -35.2 3.0 0.018 0.694 B:P32851:0.165
A:P63025:0.282
D:P60881:0.494
 CA
CA
 6.100
6.237
 CB
O
 CA
CA
LEU I:49 I:57 116.0 0.682 H -65.0 -34.7 NA NA NA
5kj8 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 LEU C:49 C:57 121.0 0.712 H -65.2 -35.5 0.0 0.0 0.712 D:P60881:0.471
A:P63025:0.312
B:P32851:0.212
 CA
CA
 6.440
7.347
 CB
O
 CA
CA
LEU I:49 I:57 115.0 0.676 H -65.1 -35.3 NA NA NA
6wvw 3 P60881 90.54 5e-39 X-RAY
 2021-03-17 LEU C:48 C:57 114.0 0.671 H -64.5 -35.5 1.0 0.006 0.665 D:P60881:0.471
B:P32851:0.171
A:P63045:0.218
 CA
HOH
 3.779
4.449
 HB2
HD12
 CA
O
LEU G:48 G:57 118.0 0.694 H -66.3 -35.6 NA NA NA
1kil 3 P60880 91.55 1e-37 X-RAY
 2002-03-13 LEU C:49 C:57 113.0 0.665 H -61.6 -38.6 1.0 0.006 0.659 D:P60880:0.453
B:P32851:0.176
A:P63045:0.265
 MG
HOH
 6.816
4.356
 CB
CB
 MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 100.0 1e-150 LEU A:57 A:57 24.0 0.141 H -66.2 -37.9