Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10273842 . A C CCDS13110.1:NM_130811.2:c.197cAa>cCa_NP_570824.1:p.66Q>P Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 95.59 1e-141 EM
 2018-09-19 HIS G:69 H:66 112.0 0.574 H -80.1 -24.1 75.0 0.385 0.189 H:P32851:0.19
6mdn 2 P60881 95.59 1e-141 EM
 2018-09-19 HIS G:69 H:66 110.0 0.564 H -76.2 -31.7 57.0 0.292 0.272 J:P54921:0.082
H:P32851:0.272
6mdo 2 P60881 95.59 1e-141 EM
 2018-09-19 HIS G:69 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 95.59 1e-141 EM
 2018-09-19 HIS G:69 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 96.97 1e-140 EM
 2015-01-28 HIS M:60 M:66 110.0 0.564 H -76.0 -41.7 22.0 0.113 0.451 I:P54921:0.179
L:P32851:0.277
3j96 5 ? 96.81 2e-133 EM
 2015-01-28 HIS M:50 M:66 109.0 0.559 H -65.2 -45.0 11.0 0.056 0.503 L:P32851:0.256
I:P54921:0.262
3j98 5 ? 96.81 2e-133 EM
 2015-01-28 HIS M:50 M:66 114.0 0.585 H -66.9 -42.0 29.0 0.149 0.436 I:P54921:0.179
L:P32851:0.267
3j99 5 ? 96.81 2e-133 EM
 2015-01-28 HIS M:50 M:66 111.0 0.569 H -66.9 -42.0 31.0 0.159 0.41 I:P54921:0.144
L:P32851:0.262
6ip1 3 P60881 100.0 1e-66 EM
 2019-04-24 GLN C:68 C:66 118.0 0.656 H -51.5 -24.5 38.0 0.211 0.445 B:P32851:0.106
G:A5D7S0:0.344
1jth 1 P60881 100.0 1e-49 X-RAY
 2001-11-28 GLN A:66 A:66 125.0 0.694 H -65.0 -46.6 71.0 0.394 0.3 D:P32851:0.3
 HOH
 5.999
 N
 O
GLN C:66 C:66 95.0 0.528 H -60.3 -44.4 61.0 0.339 0.189 B:P32851:0.189
 HOH
 2.476
 OE1
 O
1sfc 3 P60881 92.77 9e-47 X-RAY
 1998-10-28 HIS C:66 C:66 98.0 0.503 H -61.0 -52.9 77.0 0.395 0.108 B:P32851:0.108
HIS G:66 G:66 102.0 0.523 H -62.3 -44.2 NA NA NA
HIS K:66 K:66 103.0 0.528 H -63.1 -39.9 NA NA NA
1urq 3 P13795 89.87 1e-42 X-RAY
 2004-08-26 HIS C:63 C:66 115.0 0.59 H -63.1 -45.0 76.0 0.39 0.2 B:P32851:0.2
 HOH
 2.924
 ND1
 O
3hd7 3 P60881 89.87 1e-42 X-RAY
 2009-07-14 HIS C:63 C:66 119.0 0.61 H -54.7 -58.1 75.0 0.385 0.225 B:P32851:0.226
 SO4
 9.337
 O
 O2
HIS G:63 G:66 118.0 0.605 H -54.5 -56.4 NA NA NA
3ipd 3 P60881 89.87 1e-42 X-RAY
 2009-09-01 HIS C:63 C:66 120.0 0.615 H -57.8 -43.3 83.0 0.426 0.189 B:P32851:0.19
HIS G:63 G:66 119.0 0.61 H -58.0 -42.7 NA NA NA
1n7s 3 P60881 92.21 2e-42 X-RAY
 2002-12-27 HIS C:62 C:66 108.0 0.554 H -63.3 -45.6 61.0 0.313 0.241 B:P32851:0.241
 HOH
 2.680
 ND1
 O
2n1t 3 P60880 92.21 2e-42 NMR
 2015-06-03 HIS C:60 C:66 97.0 0.497 H -62.0 -42.6 87.0 0.446 0.051 B:P32851:0.051
5ccg 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 HIS C:60 C:66 123.0 0.631 H -62.4 -42.7 100.0 0.513 0.118 B:P32851:0.118
HIS I:60 I:66 121.0 0.621 H -62.7 -44.1 NA NA NA
5cch 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 HIS C:60 C:66 107.0 0.549 H -60.5 -45.2 63.0 0.323 0.226 B:P32851:0.226
5cci 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 HIS C:60 C:66 106.0 0.544 H -57.6 -45.4 58.0 0.297 0.247 B:P32851:0.246
5w5c 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 HIS C:60 C:66 111.0 0.569 H -76.6 -36.8 89.0 0.456 0.113 B:P32851:0.113
5w5d 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 HIS C:60 C:66 133.0 0.682 H -68.1 -42.4 89.0 0.456 0.226 B:P32851:0.226
6mti 5 P60881 92.21 2e-42 EM
 2019-04-24 HIS I:60 C:66 108.0 0.554 H -57.6 -45.4 60.0 0.308 0.246 H:P32851:0.246
HIS M:60 G:66 107.0 0.549 H -57.7 -45.4 59.0 0.303 0.246 L:P32851:0.246
HIS Q:60 K:66 108.0 0.554 H -57.7 -45.4 60.0 0.308 0.246 P:P32851:0.246
HIS U:60 O:66 108.0 0.554 H -57.7 -45.5 61.0 0.313 0.241 T:P32851:0.241
HIS Y:60 S:66 109.0 0.559 H -57.6 -45.5 59.0 0.303 0.256 X:P32851:0.256
HIS CA:60 W:66 110.0 0.564 H -57.6 -45.5 63.0 0.323 0.241 BA:P32851:0.241
5low 2 P60881 92.11 8e-42 X-RAY
 2017-06-21 HIS D:79 D:66 90.0 0.462 H -64.2 -48.9 83.0 0.426 0.036 F:P60881:0.036
 HOH
 7.882
 NE2
 O
HIS F:79 F:66 97.0 0.497 H -59.0 -38.6 97.0 0.497 0.0 HOH
 3.235
 O
 O
HIS K:79 K:66 114.0 0.585 H -65.0 -51.3 NA NA NA
HIS M:79 M:66 106.0 0.544 H -67.4 -40.4 NA NA NA
5lob 2 P60881 92.11 9e-42 X-RAY
 2017-06-21 HIS D:84 D:66 106.0 0.544 H -65.4 -27.7 86.0 0.441 0.103 F:P60881:0.103
HIS F:84 F:66 108.0 0.554 H -62.3 -41.3 103.0 0.528 0.026 D:P60881:0.026
3rk2 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 HIS C:64 C:66 120.0 0.615 H -51.1 -57.1 66.0 0.338 0.277 B:P32851:0.277
 HOH
 3.066
 CE1
 O
HIS G:64 G:66 122.0 0.626 H -54.2 -51.0 NA NA NA
3rk3 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 HIS C:64 C:66 117.0 0.6 H -49.4 -39.7 107.0 0.549 0.051 B:P32851:0.051
3rl0 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 HIS C:64 C:66 98.0 0.503 H -60.0 -47.4 69.0 0.354 0.149 B:P32851:0.149
HIS G:64 G:66 98.0 0.503 H -60.4 -46.7 NA NA NA
HIS K:64 K:66 96.0 0.492 H -59.8 -48.0 NA NA NA
HIS O:64 O:66 95.0 0.487 H -60.1 -47.7 NA NA NA
HIS S:64 S:66 97.0 0.497 H -60.5 -46.9 NA NA NA
HIS W:64 W:66 96.0 0.492 H -59.8 -47.7 NA NA NA
HIS AA:64 a:66 97.0 0.497 H -59.9 -47.5 NA NA NA
HIS EA:64 e:66 98.0 0.503 H -59.8 -48.2 NA NA NA
5kj7 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 HIS C:58 C:66 122.0 0.626 H -62.2 -40.7 98.0 0.503 0.123 B:P32851:0.123
HIS I:58 I:66 116.0 0.595 H -62.4 -41.9 NA NA NA
5kj8 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 HIS C:58 C:66 121.0 0.621 H -60.7 -42.7 85.0 0.436 0.185 B:P32851:0.185
HIS I:58 I:66 116.0 0.595 H -60.9 -45.3 NA NA NA
6wvw 3 P60881 90.54 5e-39 X-RAY
 2021-03-17 HIS C:57 C:66 109.0 0.559 H -61.7 -43.8 69.0 0.354 0.205 B:P32851:0.205
 HOH
 2.610
 HD2
 O
HIS G:57 G:66 120.0 0.615 H -66.6 -39.3 NA NA NA
1kil 3 P60880 91.55 1e-37 X-RAY
 2002-03-13 HIS C:58 C:66 105.0 0.538 H -62.7 -47.8 59.0 0.303 0.235 B:P32851:0.236
 HOH
 2.573
 NE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 100.0 1e-150 GLN A:66 A:66 89.0 0.494 H -66.6 -47.8