Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10273857 . T A CCDS13110.1:NM_130811.2:c.212aTg>aAg_NP_570824.1:p.71M>K Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 95.59 1e-141 EM
 2018-09-19 MET G:74 H:71 24.0 0.13 H -96.3 -6.9 2.0 0.011 0.119 H:P32851:0.103
I:P63045:0.038
6mdn 2 P60881 95.59 1e-141 EM
 2018-09-19 MET G:74 H:71 21.0 0.114 H -82.4 -12.9 10.0 0.054 0.06 H:P32851:0.038
I:P63045:0.027
6mdo 2 P60881 95.59 1e-141 EM
 2018-09-19 MET G:74 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 95.59 1e-141 EM
 2018-09-19 MET G:74 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 96.97 1e-140 EM
 2015-01-28 MET M:65 M:71 35.0 0.189 H -65.6 -44.1 5.0 0.027 0.162 L:P32851:0.065
K:P63045:0.114
3j96 5 ? 96.81 2e-133 EM
 2015-01-28 MET M:55 M:71 24.0 0.13 H -59.7 -33.7 2.0 0.011 0.119 L:P32851:0.097
K:P63045:0.038
3j98 5 ? 96.81 2e-133 EM
 2015-01-28 MET M:55 M:71 31.0 0.168 H -53.8 -37.7 1.0 0.005 0.163 L:P32851:0.081
K:P63045:0.114
3j99 5 ? 96.81 2e-133 EM
 2015-01-28 MET M:55 M:71 29.0 0.157 H -53.9 -37.8 1.0 0.005 0.152 L:P32851:0.076
K:P63045:0.108
6ip1 3 P60881 100.0 1e-66 EM
 2019-04-24 MET C:73 C:71 123.0 0.665 H -64.6 -37.2 18.0 0.097 0.568 D:P60881:0.308
B:P32851:0.227
A:P63045:0.119
1jth 1 P60881 100.0 1e-49 X-RAY
 2001-11-28 MET A:71 A:71 157.0 0.849 H -68.4 -39.0 68.0 0.368 0.481 B:P32851:0.308
D:P32851:0.135
C:P60881:0.108
 HOH
 9.562
 CE
 O
MET C:71 C:71 120.0 0.649 H -62.5 -41.1 13.0 0.07 0.579 B:P32851:0.108
D:P32851:0.368
A:P60881:0.27
 HOH
 7.786
 N
 O
1sfc 3 P60881 92.77 9e-47 X-RAY
 1998-10-28 MET C:71 C:71 96.0 0.519 H -58.9 -13.4 0.0 0.0 0.519 B:P32851:0.173
D:P60881:0.314
A:P63045:0.195
MET G:71 G:71 91.0 0.492 H -67.4 -27.9 NA NA NA
MET K:71 K:71 87.0 0.47 H -64.7 -30.4 NA NA NA
1urq 3 P13795 89.87 1e-42 X-RAY
 2004-08-26 MET C:68 C:71 89.0 0.481 H -63.5 -31.8 0.0 0.0 0.481 B:P32851:0.108
D:P13795:0.346
A:Q9Z152:0.141
 HOH
 4.388
 CE
 O
3hd7 3 P60881 89.87 1e-42 X-RAY
 2009-07-14 MET C:68 C:71 119.0 0.643 H -56.3 -21.5 4.0 0.022 0.621 B:P32851:0.119
D:P60881:0.47
A:P63045:0.13
 SO4
 6.816
 CB
 O2
MET G:68 G:71 119.0 0.643 H -62.0 -28.7 NA NA NA
3ipd 3 P60881 89.87 1e-42 X-RAY
 2009-09-01 MET C:68 C:71 117.0 0.632 H -71.3 -36.9 24.0 0.13 0.502 B:P32851:0.092
D:P60881:0.427
MET G:68 G:71 119.0 0.643 H -71.0 -36.7 NA NA NA
1n7s 3 P60881 92.21 2e-42 X-RAY
 2002-12-27 MET C:67 C:71 110.0 0.595 H -68.6 -28.1 3.0 0.016 0.579 A:P63045:0.135
B:P32851:0.124
D:P60881:0.427
 HOH
 3.105
 O
 O
2n1t 3 P60880 92.21 2e-42 NMR
 2015-06-03 MET C:65 C:71 111.0 0.6 H -62.3 -35.7 3.0 0.016 0.584 A:P63045:0.146
B:P32851:0.124
D:P60880:0.411
5ccg 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 MET C:65 C:71 111.0 0.6 H -65.4 -31.3 0.0 0.0 0.6 B:P32851:0.141
D:P60881:0.438
A:P63045:0.162
MET I:65 I:71 105.0 0.568 H -64.8 -31.4 NA NA NA
5cch 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 MET C:65 C:71 116.0 0.627 H -70.9 -30.0 1.0 0.005 0.622 B:P32851:0.119
D:P60881:0.476
A:P63045:0.146
5cci 3 P60881 92.21 2e-42 X-RAY
 2015-08-12 MET C:65 C:71 118.0 0.638 H -70.8 -25.0 1.0 0.005 0.633 B:P32851:0.135
D:P60881:0.476
A:P63045:0.162
5w5c 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 MET C:65 C:71 131.0 0.708 H -68.5 -50.8 27.0 0.146 0.562 B:P32851:0.07
D:P60881:0.497
5w5d 3 P60881 92.21 2e-42 X-RAY
 2017-08-23 MET C:65 C:71 186.0 1.0 -72.5 360.0 94.0 0.508 0.492 D:P60881:0.465
B:P32851:0.032
6mti 5 P60881 92.21 2e-42 EM
 2019-04-24 MET I:65 C:71 118.0 0.638 H -70.8 -25.1 1.0 0.005 0.633 J:P60881:0.481
G:P63045:0.168
H:P32851:0.135
MET M:65 G:71 117.0 0.632 H -70.8 -25.0 1.0 0.005 0.627 N:P60881:0.465
K:P63045:0.162
L:P32851:0.146
MET Q:65 K:71 120.0 0.649 H -70.8 -25.0 1.0 0.005 0.644 P:P32851:0.141
R:P60881:0.486
O:P63045:0.173
MET U:65 O:71 117.0 0.632 H -70.8 -25.0 1.0 0.005 0.627 V:P60881:0.476
T:P32851:0.141
S:P63045:0.162
MET Y:65 S:71 117.0 0.632 H -70.8 -25.1 1.0 0.005 0.627 X:P32851:0.141
W:P63045:0.162
Z:P60881:0.476
MET CA:65 W:71 118.0 0.638 H -70.7 -25.1 1.0 0.005 0.633 BA:P32851:0.135
AA:P63045:0.168
DA:P60881:0.481
5low 2 P60881 92.11 8e-42 X-RAY
 2017-06-21 MET D:84 D:71 167.0 0.903 T -72.2 -28.2 37.0 0.2 0.703 F:P60881:0.33
E:P60881:0.438
 HOH
 7.388
 O
 O
MET F:84 F:71 128.0 0.692 H -67.0 -33.6 4.0 0.022 0.67 D:P60881:0.362
G:P60881:0.47
 HOH
 7.332
 N
 O
MET K:84 K:71 135.0 0.73 T -77.5 146.5 NA NA NA
MET M:84 M:71 109.0 0.589 H -68.0 -48.6 NA NA NA
5lob 2 P60881 92.11 9e-42 X-RAY
 2017-06-21 MET D:89 D:71 102.0 0.551 H -75.9 -44.7 0.0 0.0 0.551 F:P60881:0.319
E:P60881:0.314
MET F:89 F:71 126.0 0.681 H -68.8 -29.5 6.0 0.032 0.649 G:P60881:0.432
D:P60881:0.351
3rk2 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 MET C:69 C:71 94.0 0.508 H -70.0 -27.7 11.0 0.059 0.449 D:P60880:0.368
B:P32851:0.086
 HOH
 7.407
 N
 O
MET G:69 G:71 95.0 0.514 H -70.8 -25.9 NA NA NA
3rk3 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 MET C:69 C:71 142.0 0.768 H -62.1 -19.1 29.0 0.157 0.611 B:P32851:0.086
D:P60880:0.53
3rl0 3 P60880 92.11 1e-41 X-RAY
 2011-07-27 MET C:69 C:71 110.0 0.595 H -70.6 -46.3 20.0 0.108 0.487 D:P60880:0.449
B:P32851:0.038
MET G:69 G:71 103.0 0.557 H -69.9 -46.9 NA NA NA
MET K:69 K:71 99.0 0.535 H -71.1 -47.5 NA NA NA
MET O:69 O:71 120.0 0.649 H -70.5 -47.0 NA NA NA
MET S:69 S:71 108.0 0.584 H -70.2 -46.8 NA NA NA
MET W:69 W:71 116.0 0.627 H -71.1 -45.5 NA NA NA
MET AA:69 a:71 101.0 0.546 H -70.4 -47.0 NA NA NA
MET EA:69 e:71 92.0 0.497 H -70.2 -49.8 NA NA NA
5kj7 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 MET C:63 C:71 113.0 0.611 H -64.7 -30.8 0.0 0.0 0.611 B:P32851:0.146
A:P63025:0.157
D:P60881:0.443
MET I:63 I:71 106.0 0.573 H -64.2 -31.6 NA NA NA
5kj8 3 P60881 92.0 6e-41 X-RAY
 2016-10-19 MET C:63 C:71 116.0 0.627 H -66.0 -31.3 0.0 0.0 0.627 D:P60881:0.465
A:P63025:0.162
B:P32851:0.124
MET I:63 I:71 107.0 0.578 H -65.4 -30.8 NA NA NA
6wvw 3 P60881 90.54 5e-39 X-RAY
 2021-03-17 MET C:62 C:71 115.0 0.622 H -74.2 -32.2 2.0 0.011 0.611 D:P60881:0.422
B:P32851:0.135
A:P63045:0.173
 HOH
 2.850
 O
 O
MET G:62 G:71 111.0 0.6 H -76.0 -32.9 NA NA NA
1kil 3 P60880 91.55 1e-37 X-RAY
 2002-03-13 MET C:63 C:71 90.0 0.486 H -62.0 -27.8 0.0 0.0 0.486 D:P60880:0.351
B:P32851:0.103
A:P63045:0.146
 HOH
 5.235
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 100.0 1e-150 MET A:71 A:71 19.0 0.103 H -66.8 -35.7