Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10280050 . T A CCDS13109.1:NM_003081.3:c.542aTc>aAc_NP_003072.2:p.181I>N Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:184 H:181 29.0 0.166 H -57.8 -49.8 18.0 0.103 0.063 I:P63045:0.063
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:184 H:181 35.0 0.2 H -65.0 -42.0 11.0 0.063 0.137 I:P63045:0.137
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:184 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 ILE G:184 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 ILE M:175 M:181 20.0 0.114 H -84.6 -39.8 2.0 0.011 0.103 L:P32851:0.011
K:P63045:0.091
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:165 M:181 22.0 0.126 H -69.0 -54.3 7.0 0.04 0.086 K:P63045:0.08
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:165 M:181 29.0 0.166 H -59.1 -52.8 6.0 0.034 0.132 K:P63045:0.131
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 ILE M:165 M:181 29.0 0.166 H -59.2 -52.7 6.0 0.034 0.132 K:P63045:0.131
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 ILE D:62 D:181 91.0 0.52 H -42.2 -44.7 0.0 0.0 0.52 B:P32851:0.011
C:P60881:0.446
A:P63045:0.149
 SR
HOH
 9.148
7.482
 CD1
CD1
 SR
O
ILE H:62 H:181 86.0 0.491 H -52.6 -47.4 NA NA NA
ILE L:62 L:181 95.0 0.543 H -60.8 -48.5 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 ILE D:58 D:181 104.0 0.594 H -72.2 -25.7 3.0 0.017 0.577 B:P32851:0.006
C:P60881:0.497
A:P63045:0.086
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 ILE D:51 D:181 98.0 0.56 H -66.7 -44.5 3.0 0.017 0.543 A:P63045:0.08
C:P60880:0.463
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 ILE D:43 D:181 89.0 0.509 H -60.8 -41.6 0.0 0.0 0.509 B:P32851:0.034
C:P60881:0.411
A:P63045:0.131
 HOH
 4.925
 N
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ILE D:41 D:181 101.0 0.577 H -64.7 -35.8 0.0 0.0 0.577 A:P63025:0.143
B:P32851:0.034
C:P60881:0.457
 CA
CA
 9.140
7.041
 CD1
CG1
 CA
CA
ILE J:41 J:181 93.0 0.531 H -65.1 -36.1 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ILE D:41 D:181 96.0 0.549 H -61.8 -41.4 0.0 0.0 0.549 A:P63025:0.126
B:P32851:0.006
C:P60881:0.463
 CA
CA
 8.989
8.211
 CD1
CG1
 CA
CA
ILE J:41 J:181 93.0 0.531 H -62.1 -40.8 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 ILE D:41 D:181 93.0 0.531 H -64.0 -38.7 0.0 0.0 0.531 B:P32851:0.017
C:P60881:0.423
A:P63045:0.143
 CA
HOH
 6.810
3.381
 HD11
HG23
 CA
O
ILE H:41 H:181 96.0 0.549 H -63.9 -40.2 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 ILE D:45 D:181 93.0 0.531 H -55.1 -40.9 0.0 0.0 0.531 B:P32851:0.006
C:P60881:0.434
A:P63045:0.137
ILE H:45 H:181 90.0 0.514 H -56.1 -35.5 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 ILE D:45 D:181 103.0 0.589 H -56.5 -34.8 8.0 0.046 0.543 A:P63045:0.131
C:P60881:0.423
ILE H:45 H:181 102.0 0.583 H -56.3 -34.3 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:42 D:181 101.0 0.577 H -62.8 -39.1 0.0 0.0 0.577 B:P32851:0.029
C:P60881:0.457
A:P63045:0.143
 CA
CA
 9.318
7.380
 CD1
CG1
 CA
CA
ILE J:42 J:181 92.0 0.526 H -63.6 -39.2 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:42 D:181 89.0 0.509 H -57.6 -45.4 0.0 0.0 0.509 B:P32851:0.017
C:P60881:0.4
A:P63045:0.137
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ILE D:42 D:181 89.0 0.509 H -60.8 -43.3 1.0 0.006 0.503 B:P32851:0.006
C:P60881:0.394
A:P63045:0.131
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ILE D:42 D:181 105.0 0.6 H -59.7 -40.4 1.0 0.006 0.594 B:P32851:0.034
C:P60881:0.503
A:P63045:0.114
 MG
HOH
 9.792
6.825
 CD1
N
 MG
O
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ILE D:42 D:181 100.0 0.571 H -61.5 -39.7 2.0 0.011 0.56 B:P32851:0.034
C:P60881:0.469
A:P63045:0.091
 HOH
 8.031
 CD1
 O
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 ILE J:42 D:181 89.0 0.509 H -60.7 -43.3 1.0 0.006 0.503 G:P63045:0.137
I:P60881:0.4
ILE N:42 H:181 89.0 0.509 H -60.7 -43.3 1.0 0.006 0.503 L:P32851:0.006
M:P60881:0.394
K:P63045:0.126
ILE R:42 L:181 90.0 0.514 H -60.7 -43.3 1.0 0.006 0.508 Q:P60881:0.406
P:P32851:0.006
O:P63045:0.131
ILE V:42 P:181 88.0 0.503 H -60.7 -43.3 1.0 0.006 0.497 T:P32851:0.006
S:P63045:0.131
U:P60881:0.394
ILE Z:42 T:181 91.0 0.52 H -60.7 -43.4 1.0 0.006 0.514 W:P63045:0.149
Y:P60881:0.406
X:P32851:0.006
ILE DA:42 X:181 90.0 0.514 H -60.7 -43.3 0.0 0.0 0.514 AA:P63045:0.137
CA:P60881:0.4
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 ILE D:46 D:180 93.0 0.531 H -57.9 -43.2 0.0 0.0 0.531 B:P32851:0.04
C:P13795:0.446
A:Q9Z152:0.149
 HOH
 4.964
 N
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 ILE E:60 E:181 92.0 0.526 H -65.5 -48.8 3.0 0.017 0.509 D:P60881:0.406
G:P60881:0.109
F:P60881:0.057
 HOH
 7.993
 CG1
 O
ILE G:60 G:181 112.0 0.64 H -60.3 -35.2 6.0 0.034 0.606 D:P60881:0.063
F:P60881:0.531
E:P60881:0.097
 HOH
 9.360
 N
 O
ILE L:60 L:181 97.0 0.554 H -68.8 -40.5 NA NA NA
ILE N:60 N:181 97.0 0.554 H -67.3 -41.6 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:43 D:181 99.0 0.566 H -66.4 -43.4 19.0 0.109 0.457 B:P32851:0.051
C:P60880:0.446
 HOH
 5.939
 N
 O
ILE H:43 H:181 99.0 0.566 H -67.9 -40.8 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:43 D:181 96.0 0.549 H -53.2 -41.4 23.0 0.131 0.418 B:P32851:0.051
C:P60880:0.389
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ILE D:43 D:181 95.0 0.543 H -63.3 -37.0 20.0 0.114 0.429 B:P32851:0.051
C:P60880:0.394
ILE H:43 H:181 99.0 0.566 H -63.4 -40.2 NA NA NA
ILE L:43 L:181 98.0 0.56 H -62.9 -37.2 NA NA NA
ILE P:43 P:181 99.0 0.566 H -63.0 -37.9 NA NA NA
ILE T:43 T:181 101.0 0.577 H -63.3 -39.4 NA NA NA
ILE X:43 X:181 100.0 0.571 H -63.8 -38.1 NA NA NA
ILE BA:43 b:181 98.0 0.56 H -62.8 -39.0 NA NA NA
ILE FA:43 f:181 101.0 0.577 H -63.1 -38.1 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 ILE E:74 E:181 94.0 0.537 H -79.9 -37.0 4.0 0.023 0.514 D:P60881:0.446
G:P60881:0.074
F:P60881:0.051
ILE G:74 G:181 96.0 0.549 H -76.5 -36.3 5.0 0.029 0.52 E:P60881:0.074
D:P60881:0.034
F:P60881:0.469
 SO4
 9.201
 CD1
 O3
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 ILE D:43 D:181 87.0 0.497 H -61.5 -31.0 0.0 0.0 0.497 B:P32851:0.006
C:P60880:0.411
A:P63045:0.126
 MG
HOH
 9.737
6.154
 CD1
N
 MG
O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 ILE B:36 B:181 140.0 0.8 -88.3 114.1 10.0 0.057 0.743 A:33321098:0.743
 HOH
 3.241
 CA
 O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 ILE A:487 NA:NA DO NA DO DO DO NA NA NA
ILE B:487 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 ILE A:181 A:181 18.0 0.103 H -59.9 -43.8