Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10286817 . G A CCDS13109.1:NM_003081.3:c.593cGt>cAt_NP_003072.2:p.198R>H Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 ARG G:201 H:198 138.0 0.613 H -67.4 -40.6 138.0 0.613 0.0
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 ARG G:201 H:198 133.0 0.591 H -66.0 -37.2 133.0 0.591 0.0
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 ARG G:201 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 ARG G:201 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 ARG M:192 M:198 138.0 0.613 H -69.3 -22.8 138.0 0.613 0.0
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 ARG M:182 M:198 108.0 0.48 T -86.7 7.4 108.0 0.48 0.0
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 ARG M:182 M:198 127.0 0.564 H -97.9 -23.8 127.0 0.564 0.0
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 ARG M:182 M:198 127.0 0.564 H -97.9 -23.8 127.0 0.564 0.0
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 ARG D:79 D:198 177.0 0.787 H -46.9 -73.7 115.0 0.511 0.276 C:P60881:0.276
ARG H:79 H:198 171.0 0.76 H -49.0 -60.5 NA NA NA
ARG L:79 L:198 166.0 0.738 H -76.8 -11.0 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 ARG D:75 D:198 134.0 0.596 H -77.6 -1.0 83.0 0.369 0.227 C:P60881:0.227
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 ARG D:68 D:198 137.0 0.609 H -61.7 -45.5 79.0 0.351 0.258 C:P60880:0.258
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 ARG D:60 D:198 181.0 0.804 H -61.0 -47.7 95.0 0.422 0.382 C:P60881:0.382
 HOH
 2.965
 NH1
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ARG D:58 D:198 181.0 0.804 H -63.7 -38.4 142.0 0.631 0.173 C:P60881:0.173
 HOH
 7.592
 N
 O
ARG J:58 J:198 173.0 0.769 H -63.1 -38.8 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ARG D:58 D:198 180.0 0.8 H -60.3 -39.9 130.0 0.578 0.222 C:P60881:0.222
ARG J:58 J:198 176.0 0.782 H -60.7 -40.0 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 ARG D:58 D:198 171.0 0.76 H -63.2 -50.0 88.0 0.391 0.369 C:P60881:0.369
 HOH
 5.044
 N
 O
ARG H:58 H:198 180.0 0.8 H -67.1 -48.5 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 ARG D:62 D:198 207.0 0.92 T -94.1 -14.2 123.0 0.547 0.373 C:P60881:0.373
ARG H:62 H:198 205.0 0.911 H -82.5 -14.9 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 ARG D:62 D:198 186.0 0.827 S -100.5 8.4 146.0 0.649 0.178 C:P60881:0.178
ARG H:62 H:198 184.0 0.818 S -100.4 8.3 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ARG D:59 D:198 182.0 0.809 H -61.8 -35.9 139.0 0.618 0.191 C:P60881:0.191
 HOH
 7.458
 N
 O
ARG J:59 J:198 174.0 0.773 H -60.8 -36.7 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ARG D:59 D:198 127.0 0.564 H -64.4 -37.4 73.0 0.324 0.24 C:P60881:0.24
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ARG D:59 D:198 142.0 0.631 H -64.9 -34.9 66.0 0.293 0.338 C:P60881:0.338
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ARG D:59 NA:NA DO NA DO DO DO NA NA NA
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ARG D:59 NA:NA DO NA DO DO DO NA NA NA
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 ARG J:59 D:198 142.0 0.631 H -64.9 -35.0 66.0 0.293 0.338 I:P60881:0.338
ARG N:59 H:198 145.0 0.644 H -65.0 -34.9 66.0 0.293 0.351 M:P60881:0.351
ARG R:59 L:198 145.0 0.644 H -65.0 -35.0 67.0 0.298 0.346 Q:P60881:0.347
ARG V:59 P:198 147.0 0.653 H -64.9 -35.0 69.0 0.307 0.346 U:P60881:0.347
ARG Z:59 T:198 146.0 0.649 H -64.9 -35.0 68.0 0.302 0.347 Y:P60881:0.347
ARG DA:59 X:198 145.0 0.644 H -64.9 -35.0 68.0 0.302 0.342 CA:P60881:0.342
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 ARG D:63 D:197 231.0 1.0 H -62.3 -33.8 89.0 0.396 0.604 C:P13795:0.631
 HOH
 2.759
 O
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 ARG E:77 NA:NA DO NA DO DO DO NA NA NA
ARG G:77 G:198 215.0 0.956 -88.8 -10.9 157.0 0.698 0.258 C:P47709:0.222
D:P60881:0.027
F:P60881:0.004
 HOH
 4.328
 CD
 O
ARG L:77 L:198 178.0 0.791 T -76.3 -6.0 NA NA NA
ARG N:77 N:198 248.0 1.0 -133.6 360.0 NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ARG D:60 D:198 179.0 0.796 H -65.4 -41.0 69.0 0.307 0.489 C:P60880:0.489
 HOH
 2.856
 O
 O
ARG H:60 H:198 180.0 0.8 H -63.0 -39.8 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ARG D:60 D:198 193.0 0.858 H -81.5 -37.8 185.0 0.822 0.036 C:P60880:0.036
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ARG D:60 D:198 196.0 0.871 H -76.9 -44.7 194.0 0.862 0.009 C:P60880:0.009
ARG H:60 H:198 205.0 0.911 H -76.0 -45.0 NA NA NA
ARG L:60 L:198 140.0 0.622 H -74.4 -46.7 NA NA NA
ARG P:60 P:198 150.0 0.667 H -77.6 -45.0 NA NA NA
ARG T:60 T:198 206.0 0.916 H -76.0 -45.3 NA NA NA
ARG X:60 X:198 177.0 0.787 H -76.6 -45.3 NA NA NA
ARG BA:60 b:198 215.0 0.956 H -76.0 -45.7 NA NA NA
ARG FA:60 f:198 183.0 0.813 H -76.1 -45.4 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 ARG E:91 E:198 191.0 0.849 -146.4 135.6 122.0 0.542 0.307 G:P60881:0.218
F:P60881:0.089
ARG G:91 NA:NA DO NA DO DO DO NA NA NA
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 ARG D:60 D:198 157.0 0.698 H -45.6 -49.7 89.0 0.396 0.302 C:P60880:0.302
 HOH
 3.371
 NH2
 O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 ARG B:53 B:198 178.0 0.791 T 31.7 -134.0 68.0 0.302 0.489 A:33321098:0.489
 ZN
HOH
 4.758
3.119
 O
N
 ZN
O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 ARG A:504 NA:NA DO NA DO DO DO NA NA NA
ARG B:504 NA:NA DO NA DO DO DO NA NA NA
3dda 2 P60880 100.0 1.0 X-RAY
 2008-09-16 ARG B:2 B:198 239.0 1.0 -46.7 -46.4 17.0 0.076 0.924 A:A5HZZ9:0.987
 ZN
HOH
 4.053
2.797
 N
NH2
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 ARG A:198 A:198 85.0 0.378 H -64.6 -45.5