Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 10286820 . C A CCDS13109.1:NM_003081.3:c.596gCa>gAa_NP_003072.2:p.199A>E Homo sapiens synaptosome associated protein 25kDa (SNAP25), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6mdm 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:202 H:199 39.0 0.339 H -66.0 -33.7 6.0 0.052 0.287 I:P63045:0.287
6mdn 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:202 H:199 48.0 0.417 H -76.2 -0.8 1.0 0.009 0.408 I:P63045:0.409
6mdo 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:202 NA:NA DO NA DO DO DO NA NA NA
6mdp 2 P60881 100.0 2e-149 EM
 2018-09-19 ALA G:202 NA:NA DO NA DO DO DO NA NA NA
3j97 5 ? 98.48 1e-141 EM
 2015-01-28 ALA M:193 M:199 43.0 0.374 H -82.6 -38.6 8.0 0.07 0.304 K:P63045:0.304
3j96 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:183 M:199 38.0 0.33 T -109.7 -29.0 0.0 0.0 0.33 K:P63045:0.33
3j98 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:183 M:199 37.0 0.322 H -86.2 -44.7 1.0 0.009 0.313 K:P63045:0.313
3j99 5 ? 98.4 3e-134 EM
 2015-01-28 ALA M:183 M:199 35.0 0.304 H -86.1 -44.8 1.0 0.009 0.295 K:P63045:0.296
1sfc 4 P60881 100.0 1e-56 X-RAY
 1998-10-28 ALA D:80 D:199 50.0 0.435 H -35.4 -39.8 0.0 0.0 0.435 B:P32851:0.017
C:P60881:0.139
A:P63045:0.391
ALA H:80 H:199 41.0 0.357 H -44.3 -39.8 NA NA NA
ALA L:80 L:199 36.0 0.313 H -86.2 -39.9 NA NA NA
6ip1 4 P60881 100.0 2e-52 EM
 2019-04-24 ALA D:76 D:199 73.0 0.635 H -120.7 -9.7 0.0 0.0 0.635 C:P60881:0.087
A:P63045:0.591
2n1t 4 P60880 100.0 6e-47 NMR
 2015-06-03 ALA D:69 D:199 55.0 0.478 H -64.7 -43.7 1.0 0.009 0.469 A:P63045:0.409
C:P60880:0.113
1n7s 4 P60881 100.0 9e-39 X-RAY
 2002-12-27 ALA D:61 D:199 42.0 0.365 H -60.7 -43.8 0.0 0.0 0.365 C:P60881:0.122
A:P63045:0.33
 HOH
 4.947
 N
 O
5kj7 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ALA D:59 D:199 53.0 0.461 H -61.9 -43.3 3.0 0.026 0.435 A:P63025:0.4
C:P60881:0.07
 HOH
 9.749
 N
 O
ALA J:59 J:199 61.0 0.53 H -62.2 -44.1 NA NA NA
5kj8 4 P60881 100.0 1e-38 X-RAY
 2016-10-19 ALA D:59 D:199 47.0 0.409 H -63.0 -49.6 2.0 0.017 0.392 A:P63025:0.357
C:P60881:0.061
ALA J:59 J:199 58.0 0.504 H -63.5 -49.4 NA NA NA
6wvw 4 P60881 100.0 1e-38 X-RAY
 2021-03-17 ALA D:59 D:199 45.0 0.391 H -60.3 -38.0 0.0 0.0 0.391 C:P60881:0.13
A:P63045:0.357
 HOH
 3.215
 HB3
 O
ALA H:59 H:199 42.0 0.365 H -60.9 -37.5 NA NA NA
3hd7 4 P60881 100.0 1e-38 X-RAY
 2009-07-14 ALA D:63 D:199 87.0 0.757 -76.6 -24.6 29.0 0.252 0.505 C:P60881:0.078
A:P63045:0.443
ALA H:63 H:199 85.0 0.739 -73.9 -33.4 NA NA NA
3ipd 4 P60881 100.0 1e-38 X-RAY
 2009-09-01 ALA D:63 D:199 76.0 0.661 -91.5 -34.0 32.0 0.278 0.383 A:P63045:0.383
ALA H:63 H:199 77.0 0.67 -91.3 -34.6 NA NA NA
5ccg 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:60 D:199 52.0 0.452 H -63.4 -45.2 2.0 0.017 0.435 C:P60881:0.07
A:P63045:0.391
 HOH
 9.624
 N
 O
ALA J:60 J:199 60.0 0.522 H -64.7 -46.2 NA NA NA
5cch 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:60 D:199 47.0 0.409 H -65.6 -45.4 0.0 0.0 0.409 C:P60881:0.104
A:P63045:0.374
5cci 4 P60881 100.0 1e-38 X-RAY
 2015-08-12 ALA D:60 D:199 56.0 0.487 H -70.5 -44.0 0.0 0.0 0.487 B:P32851:0.017
C:P60881:0.174
A:P63045:0.374
5w5c 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ALA D:60 NA:NA DO NA DO DO DO NA NA NA
5w5d 4 P60881 100.0 1e-38 X-RAY
 2017-08-23 ALA D:60 NA:NA DO NA DO DO DO NA NA NA
6mti 6 P60881 100.0 1e-38 EM
 2019-04-24 ALA J:60 D:199 57.0 0.496 H -70.5 -44.0 0.0 0.0 0.496 G:P63045:0.383
H:P32851:0.017
I:P60881:0.165
ALA N:60 H:199 58.0 0.504 H -70.6 -44.0 1.0 0.009 0.495 L:P32851:0.017
M:P60881:0.174
K:P63045:0.383
ALA R:60 L:199 57.0 0.496 H -70.5 -44.0 1.0 0.009 0.487 Q:P60881:0.174
P:P32851:0.017
O:P63045:0.374
ALA V:60 P:199 56.0 0.487 H -70.4 -44.1 1.0 0.009 0.478 T:P32851:0.017
S:P63045:0.374
U:P60881:0.165
ALA Z:60 T:199 57.0 0.496 H -70.5 -44.0 1.0 0.009 0.487 W:P63045:0.374
Y:P60881:0.165
X:P32851:0.009
ALA DA:60 X:199 58.0 0.504 H -70.5 -44.0 0.0 0.0 0.504 AA:P63045:0.374
BA:P32851:0.017
CA:P60881:0.174
1urq 4 P13795 98.44 2e-38 X-RAY
 2004-08-26 ALA D:64 D:198 84.0 0.73 -90.5 -10.9 18.0 0.157 0.573 C:P13795:0.209
A:Q9Z152:0.513
 HOH
 2.573
 C
 O
5low 3 P60881 100.0 6e-38 X-RAY
 2017-06-21 ALA E:78 NA:NA DO NA DO DO DO NA NA NA
ALA G:78 G:199 144.0 1.0 -109.0 360.0 139.0 1.0 0.0 C:P47709:0.043
 HOH
 9.148
 N
 O
ALA L:78 L:199 86.0 0.748 T -66.3 -14.5 NA NA NA
ALA N:78 NA:NA DO NA DO DO DO NA NA NA
3rk2 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:61 D:199 40.0 0.348 H -64.9 -43.2 34.0 0.296 0.052 C:P60880:0.052
 HOH
 4.767
 N
 O
ALA H:61 H:199 48.0 0.417 H -76.0 -30.6 NA NA NA
3rk3 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:61 D:199 67.0 0.583 H -65.8 -47.1 67.0 0.583 0.0
3rl0 4 P60880 100.0 8e-38 X-RAY
 2011-07-27 ALA D:61 D:199 71.0 0.617 H -67.0 -47.8 71.0 0.617 0.0
ALA H:61 H:199 119.0 1.0 -65.2 360.0 NA NA NA
ALA L:61 L:199 66.0 0.574 H -67.8 -48.2 NA NA NA
ALA P:61 P:199 65.0 0.565 H -61.6 -26.2 NA NA NA
ALA T:61 T:199 88.0 0.765 H -62.1 -29.7 NA NA NA
ALA X:61 X:199 89.0 0.774 H -62.7 -28.7 NA NA NA
ALA BA:61 b:199 120.0 1.0 -65.5 360.0 NA NA NA
ALA FA:61 f:199 88.0 0.765 H -63.2 -30.9 NA NA NA
5lob 3 P60881 100.0 1e-37 X-RAY
 2017-06-21 ALA E:92 E:199 75.0 0.652 -127.1 9.0 75.0 0.652 0.0
ALA G:92 NA:NA DO NA DO DO DO NA NA NA
1kil 4 P60880 100.0 1e-37 X-RAY
 2002-03-13 ALA D:61 D:199 45.0 0.391 H -51.6 -53.0 0.0 0.0 0.391 C:P60880:0.104
A:P63045:0.348
 HOH
 6.785
 CB
 O
1xtg 2 P60880 100.0 3e-35 X-RAY
 2004-12-21 ALA B:54 B:199 74.0 0.643 T -69.8 -8.9 5.0 0.043 0.6 A:33321098:0.6
 ZN
HOH
 6.555
3.093
 N
CB
 ZN
O
3zur 1 P10845,P60880 98.41 9e-34 X-RAY
 2011-12-07 ALA A:505 NA:NA DO NA DO DO DO NA NA NA
ALA B:505 NA:NA DO NA DO DO DO NA NA NA
3dda 2 P60880 100.0 1.0 X-RAY
 2008-09-16 ALA B:3 B:199 36.0 0.313 -148.6 165.3 8.0 0.07 0.243 A:A5HZZ9:0.243
 ZN
HOH
 5.497
2.659
 N
O
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60880-f1 1 P60880 95.63 1e-143 ALA A:199 A:199 26.0 0.226 H -58.8 -47.5