Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 33147190 | . | G | A | CCDS13237.1:NM_181509.2:c.148Gtc>Atc_NP_852610.1:p.50V>I | Homo sapiens microtubule associated protein 1 light chain 3 alpha (MAP1LC3A), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5cx3 | 1 | Q9H492 | 100.0 | 2e-87 |
X-RAY |
2016-08-03 | VAL | A:46 | A:46 | 99.0 | 0.639 | -82.7 | 149.1 | 43.0 | 0.277 | 0.362 |
E:Q9BQS8:0.361 |
HOH |
5.300 |
O |
O |
||
VAL | B:46 | B:46 | 99.0 | 0.639 | -85.5 | 145.9 | NA | NA | NA | ||||||||||||||
VAL | C:46 | C:46 | 68.0 | 0.439 | -85.3 | 151.7 | 68.0 | 0.439 | 0.0 |
HOH |
3.807 |
CA |
O |
||||||||||
VAL | D:46 | D:46 | 91.0 | 0.587 | -87.3 | 147.8 | NA | NA | NA | ||||||||||||||
3eci | 1 | Q9H492 | 100.0 | 3e-87 |
X-RAY |
2008-10-14 | VAL | A:47 | A:46 | 97.0 | 0.626 | -69.9 | 131.0 | 97.0 | 0.626 | 0.0 | |||||||
VAL | B:47 | B:46 | 104.0 | 0.671 | -87.9 | 124.2 | NA | NA | NA | ||||||||||||||
7r9w | 1 | Q9H492 | 100.0 | 1e-86 |
X-RAY |
2022-01-12 | VAL | A:48 | A:46 | 96.0 | 0.619 | -84.2 | 145.2 | 96.0 | 0.619 | 0.0 |
HOH |
2.348 |
O |
O |
|||
7r9z | 1 | Q9H492 | 100.0 | 1e-86 |
X-RAY |
2022-01-12 | VAL | A:48 | A:46 | 109.0 | 0.703 | -77.4 | 142.4 | 109.0 | 0.703 | 0.0 |
HOH |
3.876 |
CG2 |
O |
|||
7ra0 | 1 | Q9H492 | 100.0 | 1e-86 |
X-RAY |
2022-01-12 | VAL | A:48 | A:46 | 100.0 | 0.645 | -87.3 | 138.1 | 100.0 | 0.645 | 0.0 |
HOH |
2.989 |
N |
O |
|||
3wan | 1 | O75143,Q9H492 | 100.0 | 1e-86 |
X-RAY |
2013-12-25 | VAL | A:61 | A:62 | 92.0 | 0.594 | -100.6 | 130.8 | 92.0 | 0.594 | 0.0 |
HOH |
2.750 |
O |
O |
|||
VAL | B:61 | B:62 | 77.0 | 0.497 | -78.3 | 148.9 | 77.0 | 0.497 | 0.0 |
HOH |
2.783 |
O |
O |
||||||||||
5dpr | 1 | Q9Y4G2,Q9H492 | 100.0 | 2e-86 |
X-RAY |
2016-09-28 | VAL | A:61 | A:57 | 75.0 | 0.484 | -85.9 | 146.8 | 75.0 | 0.484 | 0.0 |
HOH |
4.551 |
HG23 |
O |
|||
VAL | B:61 | B:57 | 67.0 | 0.432 | -84.8 | 146.9 | NA | NA | NA | ||||||||||||||
VAL | C:61 | C:57 | 76.0 | 0.49 | -85.3 | 146.8 | NA | NA | NA | ||||||||||||||
VAL | D:61 | D:57 | 84.0 | 0.542 | -85.3 | 146.6 | NA | NA | NA | ||||||||||||||
3wal | 1 | Q9H492 | 100.0 | 3e-86 |
X-RAY |
2013-12-25 | VAL | A:50 | A:50 | 96.0 | 0.619 | -74.4 | 148.9 | 96.0 | 0.619 | 0.0 |
HOH |
3.883 |
O |
O |
|||
4zdv | 1 | Q9H492 | 100.0 | 3e-85 |
X-RAY |
2015-06-03 | VAL | A:58 | A:46 | 70.0 | 0.452 | -76.6 | 134.6 | 70.0 | 0.452 | 0.0 |
HOH |
2.740 |
O |
O |
|||
6tbe | 1 | Q9H492 | 100.0 | 4e-83 |
X-RAY |
2020-11-18 | VAL | A:46 | A:50 | 96.0 | 0.619 | -90.4 | 126.1 | 96.0 | 0.619 | 0.0 |
HOH |
2.909 |
N |
O |
|||
5gmv | 1 | Q9GZQ8 | 82.5 | 3e-72 |
X-RAY |
2017-03-08 | VAL | A:46 | B:46 | 95.0 | 0.613 | -79.1 | 151.9 | 95.0 | 0.613 | 0.0 |
HOH |
2.967 |
N |
O |
|||
VAL | C:46 | A:46 | 93.0 | 0.6 | -90.2 | 139.3 | NA | NA | NA | ||||||||||||||
5wrd | 1 | Q9CQV6 | 82.5 | 4e-72 |
X-RAY |
2017-03-29 | VAL | A:46 | A:46 | 107.0 | 0.69 | -88.6 | 138.4 | 107.0 | 0.69 | 0.0 |
HOH |
6.082 |
CG2 |
O |
|||
VAL | B:46 | B:46 | 108.0 | 0.697 | -79.6 | 141.3 | NA | NA | NA | ||||||||||||||
5yiq | 1 | Q9CQV6 | 82.5 | 4e-72 |
X-RAY |
2018-05-23 | VAL | A:46 | A:46 | 99.0 | 0.639 | -69.5 | 139.8 | 99.0 | 0.639 | 0.0 |
HOH |
8.397 |
N |
O |
|||
5yis | 1 | Q9CQV6 | 82.5 | 4e-72 |
X-RAY |
2018-05-23 | VAL | A:46 | A:46 | 95.0 | 0.613 | -86.1 | 125.1 | 95.0 | 0.613 | 0.0 |
HOH |
5.172 |
CG1 |
O |
|||
VAL | B:46 | B:46 | 94.0 | 0.606 | -83.8 | 134.8 | NA | NA | NA | ||||||||||||||
2k6q | 1 | Q62625 | 82.5 | 5e-72 |
NMR |
2008-09-02 | VAL | A:47 | A:46 | 94.0 | 0.606 | -73.6 | 115.1 | 94.0 | 0.606 | 0.0 | |||||||
2n9x | 1 | Q9GZQ8 | 82.5 | 5e-72 |
NMR |
2016-12-14 | VAL | A:46 | A:46 | 111.0 | 0.716 | -75.2 | 33.3 | 111.0 | 0.716 | 0.0 | |||||||
2zjd | 1 | Q9GZQ8 | 81.82 | 6e-72 |
X-RAY |
2008-06-03 | VAL | A:51 | A:46 | 97.0 | 0.626 | -79.3 | 139.4 | 97.0 | 0.626 | 0.0 |
HOH |
2.803 |
O |
O |
|||
VAL | C:51 | C:46 | 98.0 | 0.632 | -76.9 | 138.9 | NA | NA | NA | ||||||||||||||
5d94 | 1 | Q9GZQ8 | 81.82 | 6e-72 |
X-RAY |
2015-10-21 | VAL | A:51 | A:46 | 89.0 | 0.574 | -90.7 | 137.0 | 89.0 | 0.574 | 0.0 |
HOH |
2.716 |
O |
O |
|||
2z0e | 2 | Q62625 | 82.5 | 6e-72 |
X-RAY |
2007-05-22 | VAL | B:51 | B:46 | 95.0 | 0.613 | -101.9 | 146.2 | 95.0 | 0.613 | 0.0 |
HOH |
3.238 |
CG1 |
O |
|||
2zzp | 2 | Q62625 | 82.5 | 6e-72 |
X-RAY |
2009-03-03 | VAL | B:51 | B:46 | 98.0 | 0.632 | -97.9 | 139.4 | 98.0 | 0.632 | 0.0 |
HOH |
3.567 |
CG1 |
O |
|||
1ugm | 1 | Q62625 | 82.5 | 1e-71 |
X-RAY |
2004-07-06 | VAL | A:51 | A:46 | 99.0 | 0.639 | -91.9 | 147.0 | 99.0 | 0.639 | 0.0 |
HOH |
2.611 |
N |
O |
|||
2z0d | 2 | Q62625 | 82.5 | 1e-71 |
X-RAY |
2007-05-22 | VAL | B:51 | B:46 | 90.0 | 0.581 | -99.8 | 140.1 | 90.0 | 0.581 | 0.0 |
HOH |
2.924 |
N |
O |
|||
5xad | 1 | Q9GZQ8 | 82.35 | 4e-71 |
X-RAY |
2017-07-12 | VAL | A:45 | A:46 | 96.0 | 0.619 | -89.8 | 136.7 | 96.0 | 0.619 | 0.0 |
HOH |
4.226 |
CG1 |
O |
|||
VAL | B:45 | B:46 | 96.0 | 0.619 | -95.0 | 134.5 | NA | NA | NA | ||||||||||||||
6lan | 1 | Q8IVM0,Q9GZQ8 | 81.67 | 4e-71 |
X-RAY |
2020-09-30 | VAL | A:56 | A:46 | 29.0 | 0.187 | -89.6 | 135.7 | 29.0 | 0.187 | 0.0 |
HOH |
1.939 |
H |
O |
|||
5xae | 1 | Q9GZQ8 | 82.35 | 6e-71 |
X-RAY |
2017-07-12 | VAL | A:68 | A:44 | 90.0 | 0.581 | -79.6 | 144.6 | 22.0 | 0.142 | 0.439 |
B:Q9GZQ8:0.439 |
HOH |
2.898 |
N |
O |
||
VAL | B:68 | B:44 | 87.0 | 0.561 | -81.9 | 141.8 | 87.0 | 0.561 | 0.0 |
HOH |
3.233 |
CG1 |
O |
||||||||||
VAL | C:68 | C:44 | 101.0 | 0.652 | -85.7 | 144.7 | 101.0 | 0.652 | 0.0 |
HOH |
3.720 |
CG1 |
O |
||||||||||
VAL | D:68 | D:44 | 93.0 | 0.6 | -82.8 | 144.3 | 93.0 | 0.6 | 0.0 |
HOH |
2.951 |
CG2 |
O |
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5xac | 1 | Q9GZQ8 | 82.35 | 6e-71 |
X-RAY |
2017-07-12 | VAL | A:56 | A:46 | 99.0 | 0.639 | -86.0 | 139.6 | 99.0 | 0.639 | 0.0 |
HOH |
2.930 |
N |
O |
|||
VAL | B:56 | B:46 | 63.0 | 0.406 | -74.9 | 141.9 | 38.0 | 0.245 | 0.161 |
A:Q9GZQ8:0.161 |
HOH |
2.796 |
O |
O |
|||||||||
VAL | C:56 | C:46 | 98.0 | 0.632 | -77.2 | 144.3 | 98.0 | 0.632 | 0.0 |
HOH |
4.636 |
CG1 |
O |
||||||||||
VAL | D:56 | D:46 | 99.0 | 0.639 | -84.0 | 132.1 | 79.0 | 0.51 | 0.129 |
B:Q9GZQ8:0.129 |
HOH |
2.714 |
O |
O |
|||||||||
5ms2 | 2 | Q9GZQ8 | 82.35 | 1e-70 |
X-RAY |
2017-04-19 | VAL | B:51 | B:46 | 89.0 | 0.574 | -94.9 | 107.9 | 89.0 | 0.574 | 0.0 | |||||||
3vtw | 1 | Q96CV9,Q9GZQ8 | 82.2 | 3e-70 |
X-RAY |
2013-06-26 | VAL | A:76 | A:61 | 89.0 | 0.574 | -85.4 | 143.5 | 89.0 | 0.574 | 0.0 |
HOH |
3.381 |
CG2 |
O |
|||
VAL | B:76 | B:61 | 79.0 | 0.51 | -78.7 | 142.3 | NA | NA | NA | ||||||||||||||
VAL | C:76 | C:61 | 93.0 | 0.6 | -86.1 | 143.7 | NA | NA | NA | ||||||||||||||
5v4k | 1 | Q9GZQ8 | 82.2 | 4e-70 |
X-RAY |
2017-05-17 | VAL | A:59 | A:1046 | 94.0 | 0.606 | -94.3 | 147.4 | 94.0 | 0.606 | 0.0 |
HOH |
2.978 |
N |
O |
|||
VAL | B:59 | B:1046 | 98.0 | 0.632 | -94.1 | 135.6 | 98.0 | 0.632 | 0.0 |
HOH |
3.456 |
CG1 |
O |
||||||||||
6j04 | 1 | Q9GZQ8 | 82.2 | 4e-70 |
X-RAY |
2019-11-06 | VAL | A:46 | A:46 | 97.0 | 0.626 | -68.8 | 150.4 | 97.0 | 0.626 | 0.0 |
SO4 HOH |
4.705 3.395 |
CG2 CG1 |
O1 O |
|||
VAL | B:46 | B:46 | 89.0 | 0.574 | -86.5 | 133.4 | NA | NA | NA | ||||||||||||||
VAL | C:46 | C:46 | 90.0 | 0.581 | -85.9 | 134.3 | NA | NA | NA | ||||||||||||||
VAL | D:46 | D:46 | 94.0 | 0.606 | -74.0 | 149.9 | NA | NA | NA | ||||||||||||||
3wao | 1 | O75143,Q9GZQ8 | 82.2 | 5e-70 |
X-RAY |
2013-12-25 | VAL | A:61 | A:62 | 91.0 | 0.587 | -75.0 | 153.2 | 91.0 | 0.587 | 0.0 | |||||||
VAL | B:61 | B:62 | 90.0 | 0.581 | -80.1 | 125.7 | NA | NA | NA | ||||||||||||||
VAL | C:61 | C:62 | 75.0 | 0.484 | -77.0 | 132.8 | NA | NA | NA | ||||||||||||||
VAL | D:61 | D:62 | 104.0 | 0.671 | -67.2 | 134.5 | NA | NA | NA | ||||||||||||||
5dcn | 1 | Q9GZQ8 | 82.2 | 6e-70 |
X-RAY |
2016-03-09 | VAL | A:53 | A:46 | 79.0 | 0.51 | -102.3 | 148.6 | 79.0 | 0.51 | 0.0 |
SO4 HOH |
9.053 3.183 |
CG2 CG2 |
O4 O |
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3vtv | 1 | Q96CV9,Q9GZQ8 | 82.2 | 7e-70 |
X-RAY |
2013-06-26 | VAL | A:61 | A:61 | 91.0 | 0.587 | -84.4 | 145.2 | 91.0 | 0.587 | 0.0 |
HOH |
3.493 |
CG2 |
O |
|||
3x0w | 1 | Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2015-01-14 | VAL | A:61 | A:73 | 97.0 | 0.626 | -90.6 | 138.8 | 97.0 | 0.626 | 0.0 |
HOH |
3.536 |
CA |
O |
|||
VAL | B:61 | B:73 | 104.0 | 0.671 | -96.3 | 140.5 | NA | NA | NA | ||||||||||||||
4waa | 1 | Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2015-09-09 | VAL | A:61 | A:62 | 86.0 | 0.555 | -88.9 | 130.8 | 86.0 | 0.555 | 0.0 |
HOH |
3.742 |
CG1 |
O |
|||
VAL | B:61 | B:62 | 100.0 | 0.645 | -88.1 | 137.9 | 100.0 | 0.645 | 0.0 |
HOH |
2.534 |
O |
O |
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3vtu | 1 | Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2013-06-26 | VAL | A:50 | A:50 | 93.0 | 0.6 | -77.3 | 146.3 | 93.0 | 0.6 | 0.0 |
SO4 SO4 HOH |
9.491 3.381 3.624 |
CG2 O CG2 |
O3 O1 O |
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7elg | 1 | Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2021-10-13 | VAL | A:50 | A:50 | 93.0 | 0.6 | -80.8 | 147.0 | 93.0 | 0.6 | 0.0 |
HOH |
3.382 |
CG2 |
O |
|||
5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2017-04-19 | VAL | A:64 | A:46 | 93.0 | 0.6 | -100.4 | 140.7 | 93.0 | 0.6 | 0.0 |
GOL HOH |
8.553 3.364 |
CG1 CG1 |
C1 O |
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VAL | B:64 | B:46 | 97.0 | 0.626 | -105.2 | 143.9 | NA | NA | NA | ||||||||||||||
5ms6 | 1 | Q9GZQ8 | 82.2 | 9e-70 |
X-RAY |
2017-04-19 | VAL | A:64 | A:46 | 93.0 | 0.6 | -104.7 | 147.0 | 93.0 | 0.6 | 0.0 |
HOH |
3.756 |
CA |
O |
|||
VAL | B:64 | B:46 | 92.0 | 0.594 | -107.8 | 144.2 | NA | NA | NA | ||||||||||||||
2lue | 1 | Q9GZQ8 | 82.61 | 2e-68 |
NMR |
2013-07-17 | VAL | A:46 | A:46 | 93.0 | 0.6 | -87.1 | 140.5 | 93.0 | 0.6 | 0.0 | |||||||
5w9a | 2 | Q9GZQ8 | 81.58 | 1e-66 |
X-RAY |
2018-10-10 | VAL | B:43 | C:46 | 101.0 | 0.652 | -99.8 | 122.2 | 101.0 | 0.652 | 0.0 | |||||||
VAL | C:43 | D:46 | 94.0 | 0.606 | -100.6 | 121.9 | 94.0 | 0.606 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9h492-f1 | 1 | Q9H492 | 100.0 | 8e-88 | VAL | A:46 | A:46 | 76.0 | 0.49 | -83.3 | 130.9 | ||
af-q9gzq8-f1 | 1 | Q9GZQ8 | 82.5 | 1e-72 | VAL | A:46 | A:46 | 66.0 | 0.426 | -86.1 | 131.3 | ||
af-a6nce7-f1 | 1 | A6NCE7 | 80.99 | 5e-71 | VAL | A:46 | A:46 | 68.0 | 0.439 | -85.5 | 132.8 |