Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 33147254 . T A CCDS13237.1:NM_181509.2:c.212aTc>aAc_NP_852610.1:p.71I>N Homo sapiens microtubule associated protein 1 light chain 3 alpha (MAP1LC3A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5cx3 1 Q9H492 100.0 2e-87 X-RAY
 2016-08-03 ILE A:67 A:67 0.0 0.0 H -63.2 -38.9 0.0 0.0 0.0 HOH
 6.328
 O
 O
ILE B:67 B:67 0.0 0.0 H -63.0 -40.7 NA NA NA
ILE C:67 C:67 0.0 0.0 H -65.4 -37.6 0.0 0.0 0.0 HOH
 7.716
 CG2
 O
ILE D:67 D:67 0.0 0.0 H -66.4 -41.7 NA NA NA
3eci 1 Q9H492 100.0 3e-87 X-RAY
 2008-10-14 ILE A:68 A:67 0.0 0.0 H -64.9 -44.4 0.0 0.0 0.0
ILE B:68 B:67 2.0 0.011 H -68.9 -31.9 NA NA NA
7r9w 1 Q9H492 100.0 1e-86 X-RAY
 2022-01-12 ILE A:69 A:67 6.0 0.034 H -66.4 -39.5 6.0 0.034 0.0 JO4
GOL
HOH
 4.064
9.264
5.000
 CG1
CG1
N
 C11
O3
O
7r9z 1 Q9H492 100.0 1e-86 X-RAY
 2022-01-12 ILE A:69 A:67 0.0 0.0 H -67.7 -36.7 0.0 0.0 0.0 2LZ
HOH
 5.492
4.919
 CD1
N
 O15
O
7ra0 1 Q9H492 100.0 1e-86 X-RAY
 2022-01-12 ILE A:69 A:67 1.0 0.006 H -68.5 -38.1 1.0 0.006 0.0 2JI
HOH
 4.801
4.963
 CD1
N
 C1
O
3wan 1 O75143,Q9H492 100.0 1e-86 X-RAY
 2013-12-25 ILE A:82 A:83 0.0 0.0 H -63.6 -40.7 0.0 0.0 0.0 HOH
 5.947
 CD1
 O
ILE B:82 B:83 0.0 0.0 H -71.0 -38.5 0.0 0.0 0.0 HOH
 6.043
 CD1
 O
5dpr 1 Q9Y4G2,Q9H492 100.0 2e-86 X-RAY
 2016-09-28 ILE A:82 A:78 0.0 0.0 H -65.9 -26.9 0.0 0.0 0.0 HOH
 8.260
 HB
 O
ILE B:82 B:78 0.0 0.0 H -65.9 -27.1 NA NA NA
ILE C:82 C:78 0.0 0.0 H -66.1 -26.2 NA NA NA
ILE D:82 D:78 0.0 0.0 H -64.7 -25.1 NA NA NA
3wal 1 Q9H492 100.0 3e-86 X-RAY
 2013-12-25 ILE A:71 A:71 0.0 0.0 H -71.4 -35.5 0.0 0.0 0.0 HOH
 4.848
 N
 O
4zdv 1 Q9H492 100.0 3e-85 X-RAY
 2015-06-03 ILE A:79 A:67 3.0 0.017 H -70.3 -40.0 3.0 0.017 0.0 HOH
 6.202
 C
 O
6tbe 1 Q9H492 100.0 4e-83 X-RAY
 2020-11-18 ILE A:67 A:71 8.0 0.046 H -66.4 -37.7 8.0 0.046 0.0 NOV
HOH
 4.069
4.995
 CG1
N
 C24
O
5gmv 1 Q9GZQ8 82.5 3e-72 X-RAY
 2017-03-08 ILE A:67 B:67 9.0 0.051 H -64.8 -41.8 3.0 0.017 0.034 B:Q8IVP5:0.034
 HOH
 7.200
 N
 O
ILE C:67 A:67 8.0 0.046 H -67.2 -39.8 NA NA NA
5wrd 1 Q9CQV6 82.5 4e-72 X-RAY
 2017-03-29 ILE A:67 A:67 1.0 0.006 H -66.2 -35.8 1.0 0.006 0.0 GOL
HOH
 9.879
8.356
 CB
C
 O1
O
ILE B:67 B:67 0.0 0.0 H -68.2 -43.9 NA NA NA
5yiq 1 Q9CQV6 82.5 4e-72 X-RAY
 2018-05-23 ILE A:67 A:67 4.0 0.023 H -64.3 -38.6 1.0 0.006 0.017 B:O70511:0.017
5yis 1 Q9CQV6 82.5 4e-72 X-RAY
 2018-05-23 ILE A:67 A:67 0.0 0.0 H -69.4 -40.9 0.0 0.0 0.0 HOH
 4.756
 N
 O
ILE B:67 B:67 0.0 0.0 H -68.1 -40.6 NA NA NA
2k6q 1 Q62625 82.5 5e-72 NMR
 2008-09-02 ILE A:68 A:67 0.0 0.0 H -55.9 -55.4 0.0 0.0 0.0
2n9x 1 Q9GZQ8 82.5 5e-72 NMR
 2016-12-14 ILE A:67 A:67 7.0 0.04 H -68.8 -41.2 4.0 0.023 0.017 B:Q8IVP5:0.017
2zjd 1 Q9GZQ8 81.82 6e-72 X-RAY
 2008-06-03 ILE A:72 A:67 6.0 0.034 H -69.0 -44.9 6.0 0.034 0.0 HOH
 4.981
 N
 O
ILE C:72 C:67 3.0 0.017 H -69.1 -44.1 NA NA NA
5d94 1 Q9GZQ8 81.82 6e-72 X-RAY
 2015-10-21 ILE A:72 A:67 0.0 0.0 H -71.6 -33.7 0.0 0.0 0.0 HOH
 4.993
 N
 O
2z0e 2 Q62625 82.5 6e-72 X-RAY
 2007-05-22 ILE B:72 B:67 2.0 0.011 H -65.7 -36.0 2.0 0.011 0.0 HOH
 6.223
 N
 O
2zzp 2 Q62625 82.5 6e-72 X-RAY
 2009-03-03 ILE B:72 B:67 3.0 0.017 H -71.1 -36.9 3.0 0.017 0.0 HOH
 5.969
 N
 O
1ugm 1 Q62625 82.5 1e-71 X-RAY
 2004-07-06 ILE A:72 A:67 3.0 0.017 H -63.9 -44.8 3.0 0.017 0.0 HOH
 5.033
 N
 O
2z0d 2 Q62625 82.5 1e-71 X-RAY
 2007-05-22 ILE B:72 B:67 0.0 0.0 H -63.4 -39.7 0.0 0.0 0.0 HOH
 6.041
 C
 O
5xad 1 Q9GZQ8 82.35 4e-71 X-RAY
 2017-07-12 ILE A:66 A:67 4.0 0.023 H -66.5 -43.1 4.0 0.023 0.0 HOH
 4.849
 N
 O
ILE B:66 B:67 3.0 0.017 H -67.2 -42.9 NA NA NA
6lan 1 Q8IVM0,Q9GZQ8 81.67 4e-71 X-RAY
 2020-09-30 ILE A:77 A:67 0.0 0.0 H -65.3 -42.9 0.0 0.0 0.0 HOH
 5.402
 HG23
 O
5xae 1 Q9GZQ8 82.35 6e-71 X-RAY
 2017-07-12 ILE A:89 A:65 4.0 0.023 H -70.9 -41.5 4.0 0.023 0.0 HOH
 5.446
 N
 O
ILE B:89 B:65 5.0 0.029 H -69.1 -37.5 0.0 0.0 0.029 A:Q9GZQ8:0.029
 HOH
 7.499
 C
 O
ILE C:89 C:65 7.0 0.04 H -71.4 -41.6 7.0 0.04 0.0 HOH
 4.828
 N
 O
ILE D:89 D:65 8.0 0.046 H -68.0 -40.0 8.0 0.046 0.0 HOH
 4.606
 N
 O
5xac 1 Q9GZQ8 82.35 6e-71 X-RAY
 2017-07-12 ILE A:77 A:67 2.0 0.011 H -71.6 -35.1 0.0 0.0 0.011 B:Q9GZQ8:0.011
 HOH
 4.897
 N
 O
ILE B:77 B:67 0.0 0.0 H -71.0 -37.3 0.0 0.0 0.0 HOH
 4.852
 N
 O
ILE C:77 C:67 0.0 0.0 H -68.0 -35.9 0.0 0.0 0.0 HOH
 5.398
 N
 O
ILE D:77 D:67 0.0 0.0 H -72.5 -36.7 0.0 0.0 0.0 HOH
 4.854
 N
 O
5ms2 2 Q9GZQ8 82.35 1e-70 X-RAY
 2017-04-19 ILE B:72 B:67 3.0 0.017 H -67.6 -28.2 3.0 0.017 0.0 HOH
 6.701
 C
 O
3vtw 1 Q96CV9,Q9GZQ8 82.2 3e-70 X-RAY
 2013-06-26 ILE A:97 A:82 8.0 0.046 H -62.8 -47.5 8.0 0.046 0.0 HOH
 6.820
 N
 O
ILE B:97 B:82 1.0 0.006 H -75.3 -33.3 NA NA NA
ILE C:97 C:82 1.0 0.006 H -72.6 -47.2 NA NA NA
5v4k 1 Q9GZQ8 82.2 4e-70 X-RAY
 2017-05-17 ILE A:80 A:1067 0.0 0.0 H -68.0 -40.1 0.0 0.0 0.0 SO4
HOH
 7.166
6.201
 N
C
 O4
O
ILE B:80 B:1067 1.0 0.006 H -64.9 -40.8 1.0 0.006 0.0 HOH
 5.224
 N
 O
6j04 1 Q9GZQ8 82.2 4e-70 X-RAY
 2019-11-06 ILE A:67 A:67 0.0 0.0 H -74.8 -40.2 0.0 0.0 0.0 HOH
 8.210
 CG2
 O
ILE B:67 B:67 0.0 0.0 H -68.5 -44.0 NA NA NA
ILE C:67 C:67 0.0 0.0 H -73.5 -40.6 NA NA NA
ILE D:67 D:67 0.0 0.0 H -70.8 -38.9 NA NA NA
3wao 1 O75143,Q9GZQ8 82.2 5e-70 X-RAY
 2013-12-25 ILE A:82 A:83 7.0 0.04 H -69.0 -49.6 7.0 0.04 0.0
ILE B:82 B:83 3.0 0.017 H -72.9 -54.7 NA NA NA
ILE C:82 C:83 2.0 0.011 H -77.5 -34.0 NA NA NA
ILE D:82 D:83 3.0 0.017 H -63.5 -44.5 NA NA NA
5dcn 1 Q9GZQ8 82.2 6e-70 X-RAY
 2016-03-09 ILE A:74 A:67 3.0 0.017 H -60.8 -41.0 3.0 0.017 0.0 HOH
 6.146
 N
 O
3vtv 1 Q96CV9,Q9GZQ8 82.2 7e-70 X-RAY
 2013-06-26 ILE A:82 A:82 5.0 0.029 H -71.7 -37.8 5.0 0.029 0.0 SO4
HOH
 8.898
4.840
 N
N
 O2
O
3x0w 1 Q9GZQ8 82.2 9e-70 X-RAY
 2015-01-14 ILE A:82 A:94 0.0 0.0 H -77.8 -41.4 0.0 0.0 0.0 HOH
 7.367
 C
 O
ILE B:82 B:94 0.0 0.0 H -77.6 -42.2 NA NA NA
4waa 1 Q9GZQ8 82.2 9e-70 X-RAY
 2015-09-09 ILE A:82 A:83 0.0 0.0 H -76.0 -37.6 0.0 0.0 0.0 HOH
 4.682
 N
 O
ILE B:82 B:83 2.0 0.011 H -67.7 -43.0 2.0 0.011 0.0 HOH
 4.858
 N
 O
3vtu 1 Q9GZQ8 82.2 9e-70 X-RAY
 2013-06-26 ILE A:71 A:71 0.0 0.0 H -73.8 -35.6 0.0 0.0 0.0 SO4
HOH
 6.913
4.788
 O
N
 O1
O
7elg 1 Q9GZQ8 82.2 9e-70 X-RAY
 2021-10-13 ILE A:71 A:71 0.0 0.0 H -71.3 -41.9 0.0 0.0 0.0 8Z6
HOH
 8.632
6.057
 CD1
C
 CAA
O
5ms5 1 Q5ZUV9,Q9GZQ8 82.2 9e-70 X-RAY
 2017-04-19 ILE A:85 A:67 1.0 0.006 H -68.7 -39.5 1.0 0.006 0.0 HOH
 5.893
 C
 O
ILE B:85 B:67 8.0 0.046 H -67.8 -41.9 NA NA NA
5ms6 1 Q9GZQ8 82.2 9e-70 X-RAY
 2017-04-19 ILE A:85 A:67 2.0 0.011 H -68.3 -43.2 2.0 0.011 0.0 HOH
 6.932
 O
 O
ILE B:85 B:67 8.0 0.046 H -67.1 -42.8 NA NA NA
2lue 1 Q9GZQ8 82.61 2e-68 NMR
 2013-07-17 ILE A:67 A:67 4.0 0.023 H -63.1 -42.4 4.0 0.023 0.0
5w9a 2 Q9GZQ8 81.58 1e-66 X-RAY
 2018-10-10 ILE B:64 C:67 0.0 0.0 H -65.1 -36.8 0.0 0.0 0.0
ILE C:64 D:67 0.0 0.0 H -65.9 -36.9 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9h492-f1 1 Q9H492 100.0 8e-88 ILE A:67 A:67 0.0 0.0 H -66.1 -40.3
af-q9gzq8-f1 1 Q9GZQ8 82.5 1e-72 ILE A:67 A:67 0.0 0.0 H -64.8 -40.9
af-a6nce7-f1 1 A6NCE7 80.99 5e-71 ILE A:67 A:67 0.0 0.0 H -66.2 -40.2