Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 39726874 . A C CCDS13312.1:NM_003286.2:c.872aAg>aCg_NP_003277.1:p.291K>T Homo sapiens topoisomerase (DNA) I (TOP1), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1k4s 4 P11387 100.0 0.0 X-RAY
 2002-12-04 LYS D:118 A:291 81.0 0.405 H -46.8 -34.6 81.0 0.405 0.0
1k4t 4 P11387 100.0 0.0 X-RAY
 2002-12-04 LYS D:118 A:291 66.0 0.33 H -66.4 -23.2 66.0 0.33 0.0 HOH
 4.676
 CD
 O
1sc7 4 P11387 100.0 0.0 X-RAY
 2005-04-19 LYS D:118 A:291 74.0 0.37 H -61.8 -33.3 74.0 0.37 0.0
1t8i 4 P11387 100.0 0.0 X-RAY
 2005-05-31 LYS D:118 A:291 77.0 0.385 H -76.3 -12.7 77.0 0.385 0.0
1tl8 4 P11387 100.0 0.0 X-RAY
 2005-06-21 LYS D:118 A:291 84.0 0.42 H -66.1 -13.1 84.0 0.42 0.0
1seu 4 P11387 99.83 0.0 X-RAY
 2005-04-19 LYS D:118 A:291 63.0 0.315 T -65.6 -24.5 63.0 0.315 0.0
1a31 3 P11387 100.0 0.0 X-RAY
 1998-08-28 LYS C:117 A:291 59.0 0.295 H -65.1 -42.2 59.0 0.295 0.0 HOH
 6.162
 N
 O
1r49 3 P11387 99.66 0.0 X-RAY
 2003-12-16 LYS C:118 A:291 66.0 0.33 H -36.8 -56.7 66.0 0.33 0.0 HOH
 3.224
 NZ
 O
1a35 3 P11387 99.83 0.0 X-RAY
 1998-08-28 LYS C:117 A:291 69.0 0.345 H -68.5 -27.9 69.0 0.345 0.0 HOH
 6.418
 NZ
 O
1a36 3 P11387 99.83 0.0 X-RAY
 1998-08-12 LYS C:117 A:291 73.0 0.365 H -61.9 -44.4 73.0 0.365 0.0 HOH
 6.913
 NZ
 O
1rrj 3 P11387 99.82 0.0 X-RAY
 2004-07-06 LYS C:91 A:291 67.0 0.335 H -69.4 -28.2 67.0 0.335 0.0 HOH
 2.963
 NZ
 O
1lpq 3 P11387 99.82 0.0 X-RAY
 2002-08-16 LYS C:90 A:291 70.0 0.35 H -71.1 -40.3 70.0 0.35 0.0 HOH
 2.570
 O
 O
1nh3 4 P11387 100.0 0.0 X-RAY
 2003-03-04 LYS D:89 A:291 41.0 NA H -87.3 3.6 41.0 NA NA
1ej9 3 P11387 99.64 0.0 X-RAY
 2000-08-03 LYS C:89 A:291 59.0 0.295 H -57.0 -30.5 59.0 0.295 0.0 HOH
 3.039
 NZ
 O
1rr8 3 P11387 99.64 0.0 X-RAY
 2004-07-06 LYS C:91 C:291 74.0 0.37 H -63.2 -30.8 74.0 0.37 0.0 HOH
 5.215
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11387-f1 1 P11387 100.0 0.0 LYS A:291 A:291 56.0 0.28 H -59.7 -37.5