Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 39726889 . A C CCDS13312.1:NM_003286.2:c.887aAc>aCc_NP_003277.1:p.296N>T Homo sapiens topoisomerase (DNA) I (TOP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1k4s 4 P11387 100.0 0.0 X-RAY
 2002-12-04 ASN D:123 A:296 35.0 0.219 -155.9 118.3 35.0 0.219 0.0
1k4t 4 P11387 100.0 0.0 X-RAY
 2002-12-04 ASN D:123 A:296 45.0 0.281 -152.1 159.5 45.0 0.281 0.0 HOH
 3.627
 CA
 O
1sc7 4 P11387 100.0 0.0 X-RAY
 2005-04-19 ASN D:123 A:296 46.0 0.287 -142.8 152.2 46.0 0.287 0.0
1t8i 4 P11387 100.0 0.0 X-RAY
 2005-05-31 ASN D:123 A:296 41.0 0.256 -143.2 156.4 41.0 0.256 0.0
1tl8 4 P11387 100.0 0.0 X-RAY
 2005-06-21 ASN D:123 A:296 40.0 0.25 -124.4 173.0 40.0 0.25 0.0
1seu 4 P11387 99.83 0.0 X-RAY
 2005-04-19 ASN D:123 A:296 47.0 0.294 -144.7 159.2 47.0 0.294 0.0
1a31 3 P11387 100.0 0.0 X-RAY
 1998-08-28 ASN C:122 A:296 62.0 0.388 -133.6 114.5 62.0 0.388 0.0 HOH
 4.369
 ND2
 O
1r49 3 P11387 99.66 0.0 X-RAY
 2003-12-16 ASN C:123 A:296 52.0 0.325 -142.3 152.4 52.0 0.325 0.0
1a35 3 P11387 99.83 0.0 X-RAY
 1998-08-28 ASN C:122 A:296 57.0 0.356 -134.8 116.8 57.0 0.356 0.0 HOH
 3.112
 OD1
 O
1a36 3 P11387 99.83 0.0 X-RAY
 1998-08-12 ASN C:122 A:296 42.0 0.263 -144.4 141.9 42.0 0.263 0.0 HOH
 4.524
 ND2
 O
1rrj 3 P11387 99.82 0.0 X-RAY
 2004-07-06 ASN C:96 A:296 46.0 0.287 -146.0 160.7 46.0 0.287 0.0 HOH
 3.566
 CB
 O
1lpq 3 P11387 99.82 0.0 X-RAY
 2002-08-16 ASN C:95 A:296 52.0 0.325 -147.2 -24.3 52.0 0.325 0.0 HOH
 6.441
 N
 O
1nh3 4 P11387 100.0 0.0 X-RAY
 2003-03-04 ASN D:94 A:296 15.0 NA -152.0 134.8 15.0 NA NA
1ej9 3 P11387 99.64 0.0 X-RAY
 2000-08-03 ASN C:94 A:296 42.0 0.263 -149.0 160.0 42.0 0.263 0.0 HOH
 3.163
 CA
 O
1rr8 3 P11387 99.64 0.0 X-RAY
 2004-07-06 ASN C:96 C:296 46.0 0.287 -142.6 164.9 46.0 0.287 0.0 HOH
 3.500
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11387-f1 1 P11387 100.0 0.0 ASN A:296 A:296 74.0 0.463 -136.4 120.3