Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 39726914 . G A CCDS13312.1:NM_003286.2:c.912caG>caA_NP_003277.1:p.304Q>Q Homo sapiens topoisomerase (DNA) I (TOP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1k4s 4 P11387 100.0 0.0 X-RAY
 2002-12-04 GLN D:131 A:304 44.0 0.244 H -53.3 -52.0 44.0 0.244 0.0
1k4t 4 P11387 100.0 0.0 X-RAY
 2002-12-04 GLN D:131 A:304 57.0 0.317 H -65.5 -36.8 57.0 0.317 0.0 HOH
 2.721
 N
 O
1sc7 4 P11387 100.0 0.0 X-RAY
 2005-04-19 GLN D:131 A:304 70.0 0.389 T -112.6 -19.7 70.0 0.389 0.0
1t8i 4 P11387 100.0 0.0 X-RAY
 2005-05-31 GLN D:131 A:304 55.0 0.306 H -75.5 -41.6 55.0 0.306 0.0
1tl8 4 P11387 100.0 0.0 X-RAY
 2005-06-21 GLN D:131 A:304 54.0 0.3 H -75.1 -40.9 54.0 0.3 0.0
1seu 4 P11387 99.83 0.0 X-RAY
 2005-04-19 GLN D:131 A:304 63.0 0.35 H -74.4 -30.4 63.0 0.35 0.0
1a31 3 P11387 100.0 0.0 X-RAY
 1998-08-28 GLN C:130 A:304 63.0 0.35 H -60.6 -38.3 63.0 0.35 0.0 HOH
 3.062
 N
 O
1r49 3 P11387 99.66 0.0 X-RAY
 2003-12-16 GLN C:131 A:304 65.0 0.361 H -74.8 -43.6 65.0 0.361 0.0
1a35 3 P11387 99.83 0.0 X-RAY
 1998-08-28 GLN C:130 A:304 81.0 0.45 H -54.4 -50.1 81.0 0.45 0.0 HOH
 2.885
 N
 O
1a36 3 P11387 99.83 0.0 X-RAY
 1998-08-12 GLN C:130 A:304 74.0 0.411 H -74.5 -44.1 74.0 0.411 0.0 HOH
 7.063
 N
 O
1rrj 3 P11387 99.82 0.0 X-RAY
 2004-07-06 GLN C:104 A:304 61.0 0.339 H -69.3 -35.3 61.0 0.339 0.0 HOH
 2.968
 N
 O
1lpq 3 P11387 99.82 0.0 X-RAY
 2002-08-16 GLN C:103 A:304 26.0 NA H -79.4 -56.7 26.0 NA NA
1nh3 4 P11387 100.0 0.0 X-RAY
 2003-03-04 GLN D:102 A:304 33.0 NA H -73.0 -22.0 33.0 NA NA
1ej9 3 P11387 99.64 0.0 X-RAY
 2000-08-03 GLN C:102 A:304 65.0 0.361 H -52.5 -36.7 65.0 0.361 0.0 HOH
 2.998
 O
 O
1rr8 3 P11387 99.64 0.0 X-RAY
 2004-07-06 GLN C:104 C:304 51.0 0.283 H -74.5 -32.6 51.0 0.283 0.0 HOH
 2.850
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11387-f1 1 P11387 100.0 0.0 GLN A:304 A:304 53.0 0.294 H -64.2 -40.6