Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 39728847 . G A CCDS13312.1:NM_003286.2:c.1127cGa>cAa_NP_003277.1:p.376R>Q Homo sapiens topoisomerase (DNA) I (TOP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1k4s 4 P11387 100.0 0.0 X-RAY
 2002-12-04 ARG D:203 A:376 62.0 0.276 -89.6 110.3 62.0 0.276 0.0
1k4t 4 P11387 100.0 0.0 X-RAY
 2002-12-04 ARG D:203 A:376 58.0 0.258 -62.3 124.3 58.0 0.258 0.0 HOH
 2.808
 NH2
 O
1sc7 4 P11387 100.0 0.0 X-RAY
 2005-04-19 ARG D:203 A:376 61.0 0.271 -71.8 132.4 61.0 0.271 0.0
1t8i 4 P11387 100.0 0.0 X-RAY
 2005-05-31 ARG D:203 A:376 68.0 0.302 -81.7 120.2 68.0 0.302 0.0
1tl8 4 P11387 100.0 0.0 X-RAY
 2005-06-21 ARG D:203 A:376 57.0 0.253 -69.1 133.0 57.0 0.253 0.0
1seu 4 P11387 99.83 0.0 X-RAY
 2005-04-19 ARG D:203 A:376 70.0 0.311 -58.2 128.5 70.0 0.311 0.0
1a31 3 P11387 100.0 0.0 X-RAY
 1998-08-28 ARG C:202 A:376 60.0 0.267 -83.7 117.6 60.0 0.267 0.0 HOH
 2.683
 NH2
 O
1r49 3 P11387 99.66 0.0 X-RAY
 2003-12-16 ARG C:203 A:376 73.0 0.324 -74.5 119.5 73.0 0.324 0.0
1a35 3 P11387 99.83 0.0 X-RAY
 1998-08-28 ARG C:202 A:376 64.0 0.284 -73.8 129.5 64.0 0.284 0.0 HOH
 2.590
 NH1
 O
1a36 3 P11387 99.83 0.0 X-RAY
 1998-08-12 ARG C:202 A:376 68.0 0.302 -86.1 120.0 68.0 0.302 0.0 HOH
 5.091
 NH2
 O
1rrj 3 P11387 99.82 0.0 X-RAY
 2004-07-06 ARG C:176 A:376 60.0 0.267 -64.5 123.7 60.0 0.267 0.0 HOH
 2.811
 NE
 O
1lpq 3 P11387 99.82 0.0 X-RAY
 2002-08-16 ARG C:175 A:376 65.0 0.289 -75.7 126.3 65.0 0.289 0.0 HOH
 2.616
 NH1
 O
1nh3 4 P11387 100.0 0.0 X-RAY
 2003-03-04 ARG D:174 A:376 50.0 0.222 -68.1 127.8 50.0 0.222 0.0
1ej9 3 P11387 99.64 0.0 X-RAY
 2000-08-03 ARG C:174 A:376 71.0 0.316 -88.9 132.0 71.0 0.316 0.0 HOH
 2.792
 NH1
 O
1rr8 3 P11387 99.64 0.0 X-RAY
 2004-07-06 ARG C:176 C:376 61.0 0.271 -73.5 124.2 61.0 0.271 0.0 HOH
 2.796
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11387-f1 1 P11387 100.0 0.0 ARG A:376 A:376 61.0 0.271 -66.5 128.6