Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 39728858 . G A CCDS13312.1:NM_003286.2:c.1138Gag>Aag_NP_003277.1:p.380E>K Homo sapiens topoisomerase (DNA) I (TOP1), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1k4s 4 P11387 100.0 0.0 X-RAY
 2002-12-04 GLU D:207 A:380 65.0 0.342 G -72.2 -13.7 65.0 0.342 0.0
1k4t 4 P11387 100.0 0.0 X-RAY
 2002-12-04 GLU D:207 A:380 80.0 0.421 G -61.4 -21.8 80.0 0.421 0.0 HOH
 5.538
 O
 O
1sc7 4 P11387 100.0 0.0 X-RAY
 2005-04-19 GLU D:207 A:380 78.0 0.411 G -76.7 4.4 78.0 0.411 0.0
1t8i 4 P11387 100.0 0.0 X-RAY
 2005-05-31 GLU D:207 A:380 76.0 0.4 G -72.4 12.3 76.0 0.4 0.0
1tl8 4 P11387 100.0 0.0 X-RAY
 2005-06-21 GLU D:207 A:380 84.0 0.442 G -77.6 13.5 84.0 0.442 0.0
1seu 4 P11387 99.83 0.0 X-RAY
 2005-04-19 GLU D:207 A:380 78.0 0.411 G -75.0 0.8 78.0 0.411 0.0
1a31 3 P11387 100.0 0.0 X-RAY
 1998-08-28 GLU C:206 A:380 75.0 0.395 G -64.6 -15.7 75.0 0.395 0.0 HOH
 3.027
 O
 O
1r49 3 P11387 99.66 0.0 X-RAY
 2003-12-16 GLU C:207 A:380 87.0 0.458 T -64.6 -9.3 87.0 0.458 0.0 HOH
 8.185
 CA
 O
1a35 3 P11387 99.83 0.0 X-RAY
 1998-08-28 GLU C:206 A:380 82.0 0.432 G -75.2 0.4 82.0 0.432 0.0 HOH
 3.169
 O
 O
1a36 3 P11387 99.83 0.0 X-RAY
 1998-08-12 GLU C:206 A:380 69.0 0.363 G -72.2 -0.9 69.0 0.363 0.0 HOH
 7.659
 OE2
 O
1rrj 3 P11387 99.82 0.0 X-RAY
 2004-07-06 GLU C:180 A:380 81.0 0.426 G -66.1 -14.8 81.0 0.426 0.0 HOH
 3.006
 O
 O
1lpq 3 P11387 99.82 0.0 X-RAY
 2002-08-16 GLU C:179 A:380 73.0 0.384 T -79.4 -19.9 73.0 0.384 0.0 HOH
 7.875
 OE2
 O
1nh3 4 P11387 100.0 0.0 X-RAY
 2003-03-04 GLU D:178 A:380 70.0 0.368 T -89.8 -3.0 70.0 0.368 0.0 HOH
 6.560
 O
 O
1ej9 3 P11387 99.64 0.0 X-RAY
 2000-08-03 GLU C:178 A:380 75.0 0.395 G -70.8 -7.1 75.0 0.395 0.0 HOH
 3.873
 CB
 O
1rr8 3 P11387 99.64 0.0 X-RAY
 2004-07-06 GLU C:180 C:380 84.0 0.442 G -70.3 2.3 84.0 0.442 0.0 HOH
 3.318
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11387-f1 1 P11387 100.0 0.0 GLU A:380 A:380 82.0 0.432 G -69.1 -10.0