Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759484 . G A CCDS13099.1:NM_001200.2:c.939tgG>tgA_NP_001191.1:p.313W>* Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 TRP A:33 A:31 88.0 0.345 T -117.8 -13.7 10.0 0.039 0.306 D:P36894:0.306
 HOH
 7.699
 CZ3
 O
TRP C:33 C:531 87.0 0.341 T -119.0 -12.5 10.0 0.039 0.302 B:P36894:0.302
 HOH
 4.329
 CE3
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 TRP A:33 B:31 98.0 0.384 T -117.5 -22.1 10.0 0.039 0.345 D:P36894:0.345
 HOH
 7.065
 CH2
 O
TRP B:33 A:31 97.0 0.38 T -121.3 -10.3 5.0 0.02 0.36 C:P36894:0.361
 HOH
 3.244
 NE1
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 TRP A:33 A:31 94.0 0.369 T -124.7 -10.8 4.0 0.016 0.353 D:P36894:0.353
 HOH
 9.944
 NE1
 O
TRP B:33 B:31 90.0 0.353 T -105.3 -13.0 8.0 0.031 0.322 C:P36894:0.322
 HOH
 6.484
 NE1
 O
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 TRP A:33 A:31 97.0 0.38 T -134.4 -10.1 5.0 0.02 0.36 D:P36894:0.361
 HOH
 7.776
 CZ3
 O
TRP B:33 B:31 95.0 0.373 T -111.8 -14.5 13.0 0.051 0.322 C:P36894:0.322
 HOH
 7.765
 CD1
 O
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 TRP A:31 A:31 93.0 0.365 T -105.7 -29.2 24.0 0.094 0.271 D:P36894:0.271
 HOH
 5.569
 CH2
 O
TRP B:31 B:31 90.0 0.353 T -118.4 -25.8 8.0 0.031 0.322 C:P36894:0.322
 HOH
 3.859
 CB
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 TRP A:31 A:31 84.0 0.329 T -120.3 -39.0 84.0 0.329 0.0 HOH
 5.235
 N
 O
TRP D:31 D:31 95.0 0.373 T -95.4 -47.0 95.0 0.373 0.0 HOH
 3.578
 N
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 TRP A:31 A:31 74.0 0.29 T -107.3 -13.3 10.0 0.039 0.251 C:P36894:0.251
 HOH
 5.561
 N
 O
TRP B:31 B:31 203.0 0.796 T -99.8 -41.1 203.0 0.796 0.0 HOH
 3.829
 N
 O
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 TRP A:31 A:31 70.0 0.275 T -105.4 -21.9 70.0 0.275 0.0 MPD
HOH
 3.933
3.783
 CH2
CD1
 C3
O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 TRP A:31 A:313 90.0 0.353 T -135.6 -24.5 20.0 0.078 0.275 C:Q96B86:0.275
TRP B:31 B:313 91.0 0.357 T -136.2 -24.5 91.0 0.357 0.0
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 TRP A:31 A:313 92.0 0.361 T -113.6 -26.9 12.0 0.047 0.314 B:Q6NW40:0.314
 SO4
SO4
 8.436
9.089
 CH2
CZ3
 O2
O2
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 TRP A:31 A:313 95.0 0.373 T -137.9 -30.7 16.0 0.063 0.31 C:Q6NW40:0.31
 HOH
 3.686
 CB
 O
TRP B:31 B:313 93.0 0.365 T -137.0 -31.0 93.0 0.365 0.0 HOH
 5.577
 N
 O
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 TRP A:31 A:313 82.0 0.322 T -104.6 -25.4 82.0 0.322 0.0 CL
HOH
 6.763
5.230
 CH2
NE1
 CL
O
TRP B:31 B:313 83.0 0.325 T -105.2 -24.5 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 TRP B:31 B:313 96.0 0.376 T -121.4 -19.4 18.0 0.071 0.305 C:Q6NW40:0.294
A:P97798:0.012
 SRT
 6.661
 CH2
 O4
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 TRP A:31 A:31 83.0 0.325 T -112.3 -19.5 9.0 0.035 0.29 B:P36894:0.29
 HOH
 3.804
 CE3
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 TRP A:31 A:31 77.0 0.302 T -122.6 -15.2 20.0 0.078 0.224 C:Q5D734:0.224
 HOH
 9.027
 C
 O
TRP B:31 B:31 79.0 0.31 T -119.2 -13.4 8.0 0.031 0.279 D:Q5D734:0.278
 HOH
 2.755
 CD1
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 TRP A:25 E:31 81.0 0.318 T -90.4 -30.7 81.0 0.318 0.0 HOH
 7.391
 CB
 O
TRP B:25 F:31 187.0 0.733 T -116.7 -34.1 187.0 0.733 0.0 HOH
 3.655
 CB
 O
TRP C:25 G:31 116.0 0.455 T -94.5 -40.1 NA NA NA
TRP D:25 H:31 92.0 0.361 T -103.9 -40.0 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 TRP A:20 A:31 69.0 0.271 T -136.1 -11.3 69.0 0.271 0.0 MPD
HOH
 3.747
7.075
 CH2
NE1
 C1
O
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 TRP A:32 A:31 92.0 0.361 T -86.2 -10.3 92.0 0.361 0.0 HOH
 3.316
 N
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 TRP A:21 X:31 72.0 0.282 T -105.6 -28.2 72.0 0.282 0.0 HOH
 4.267
 CE3
 O
TRP B:21 Y:31 59.0 0.231 T -126.9 -19.4 59.0 0.231 0.0 HOH
 3.839
 CE3
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 TRP A:313 A:313 1.0 0.004 T -118.6 -20.9