Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759507 . A C CCDS13099.1:NM_001200.2:c.962cAc>cCc_NP_001191.1:p.321H>P Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 HIS A:41 A:39 105.0 0.538 E -87.2 112.4 105.0 0.538 0.0 HOH
 3.001
 ND1
 O
HIS C:41 C:539 105.0 0.538 E -88.7 112.2 105.0 0.538 0.0 HOH
 2.774
 N
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 HIS A:41 B:39 106.0 0.544 E -79.4 107.3 106.0 0.544 0.0 HOH
 2.952
 O
 O
HIS B:41 A:39 108.0 0.554 E -77.9 109.9 108.0 0.554 0.0 HOH
 2.916
 O
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 HIS A:41 A:39 102.0 0.523 E -83.1 103.0 102.0 0.523 0.0 HOH
 6.415
 CD2
 O
HIS B:41 B:39 109.0 0.559 E -83.8 106.2 109.0 0.559 0.0 HOH
 6.273
 O
 O
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 HIS A:41 A:39 111.0 0.569 E -78.9 106.1 111.0 0.569 0.0 HOH
 6.711
 O
 O
HIS B:41 B:39 110.0 0.564 E -79.0 112.2 110.0 0.564 0.0 HOH
 3.258
 CD2
 O
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 HIS A:39 A:39 108.0 0.554 E -82.5 111.3 108.0 0.554 0.0 HOH
 2.613
 O
 O
HIS B:39 B:39 109.0 0.559 E -84.7 110.7 109.0 0.559 0.0 HOH
 2.675
 O
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 HIS A:39 A:39 107.0 0.549 E -78.9 109.1 81.0 0.415 0.134 C:P27038:0.133
 HOH
 2.779
 ND1
 O
HIS D:39 D:39 109.0 0.559 E -79.9 98.7 83.0 0.426 0.133 F:P27038:0.133
 HOH
 2.432
 ND1
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 HIS A:39 A:39 113.0 0.579 E -85.3 99.3 87.0 0.446 0.133 D:Q3KQI1:0.133
 HOH
 2.705
 NE2
 O
HIS B:39 B:39 106.0 0.544 E -85.1 107.6 106.0 0.544 0.0 HOH
 7.741
 CE1
 O
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 HIS A:39 A:39 117.0 0.6 E -82.9 96.0 117.0 0.6 0.0 HOH
 2.628
 N
 O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 HIS A:39 A:321 116.0 0.595 E -89.0 103.6 116.0 0.595 0.0
HIS B:39 B:321 117.0 0.6 E -89.4 103.5 117.0 0.6 0.0
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 HIS A:39 A:321 117.0 0.6 E -90.4 88.8 117.0 0.6 0.0 SO4
SO4
 2.805
9.499
 ND1
O
 O4
O2
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 HIS A:39 A:321 117.0 0.6 E -88.0 101.0 117.0 0.6 0.0 FLC
HOH
 6.027
4.069
 ND1
ND1
 OA2
O
HIS B:39 B:321 119.0 0.61 E -88.0 99.0 119.0 0.61 0.0 HOH
 3.313
 O
 O
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 HIS A:39 A:321 112.0 0.574 E -81.3 100.8 112.0 0.574 0.0 HOH
 8.690
 CB
 O
HIS B:39 B:321 112.0 0.574 E -82.9 100.6 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 HIS B:39 B:321 121.0 0.621 E -87.0 99.5 121.0 0.621 0.0 SRT
SRT
ACT
 8.872
3.489
9.239
 CB
NE2
N
 O11
C3
O
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 HIS A:39 A:39 105.0 0.538 E -81.5 108.3 103.0 0.528 0.01 C:Q3KQI1:0.01
 HOH
 2.718
 O
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 HIS A:39 A:39 118.0 0.605 E -84.6 96.2 118.0 0.605 0.0 HOH
 2.857
 ND1
 O
HIS B:39 B:39 122.0 0.626 E -84.6 102.9 122.0 0.626 0.0 HOH
 2.730
 CD2
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 HIS A:33 E:39 117.0 0.6 E -81.8 89.7 117.0 0.6 0.0 BMA
MAN
MAN
HOH
 9.985
5.905
5.679
9.795
 O
O
CD2
N
 O3
O4
O4
O
HIS B:33 F:39 114.0 0.585 E -83.9 98.9 114.0 0.585 0.0 MAN
MAN
HOH
 6.451
5.054
9.636
 O
CD2
N
 C6
O4
O
HIS C:33 G:39 111.0 0.569 E -85.3 84.9 NA NA NA
HIS D:33 H:39 110.0 0.564 E -80.2 95.7 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 HIS A:28 A:39 116.0 0.595 E -87.4 98.0 116.0 0.595 0.0 HOH
 6.164
 N
 O
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 HIS A:40 A:39 116.0 0.595 E -91.0 96.8 116.0 0.595 0.0 HOH
 2.805
 ND1
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 HIS A:29 X:39 118.0 0.605 E -85.0 99.5 118.0 0.605 0.0 HOH
 3.933
 CE1
 O
HIS B:29 Y:39 115.0 0.59 E -84.0 90.1 115.0 0.59 0.0 BMA
MAN
MAN
HOH
 9.939
5.995
4.823
3.110
 O
O
CD2
N
 O3
C6
O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 HIS A:321 A:321 109.0 0.559 E -79.8 91.0