Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759597 . C A CCDS13099.1:NM_001200.2:c.1052tCt>tAt_NP_001191.1:p.351S>Y Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 SER A:71 A:69 77.0 0.67 H -70.1 -29.0 17.0 0.148 0.522 B:P36894:0.522
 HOH
 3.073
 OG
 O
SER C:71 C:569 76.0 0.661 H -72.1 -27.9 16.0 0.139 0.522 D:P36894:0.522
 HOH
 3.029
 OG
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 SER A:71 B:69 82.0 0.713 H -68.4 -12.2 10.0 0.087 0.626 C:P36894:0.626
 HOH
 3.233
 CB
 O
SER B:71 A:69 83.0 0.722 H -84.0 -18.1 18.0 0.157 0.565 D:P36894:0.565
 HOH
 3.912
 N
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 SER A:71 A:69 79.0 0.687 H -76.5 -20.0 11.0 0.096 0.591 C:P36894:0.591
 HOH
 6.505
 OG
 O
SER B:71 B:69 80.0 0.696 H -70.4 -17.7 10.0 0.087 0.609 D:P36894:0.609
 HOH
 3.467
 N
 O
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 SER A:71 A:69 81.0 0.704 H -70.8 -13.4 17.0 0.148 0.556 C:P36894:0.557
 HOH
 6.279
 OG
 O
SER B:71 B:69 79.0 0.687 T -72.4 -15.7 13.0 0.113 0.574 D:P36894:0.574
 HOH
 3.041
 CB
 O
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 SER A:69 A:69 77.0 0.67 H -71.9 -23.5 17.0 0.148 0.522 C:P36894:0.522
 HOH
 2.987
 O
 O
SER B:69 B:69 78.0 0.678 H -61.8 -29.3 15.0 0.13 0.548 D:P36894:0.548
 HOH
 3.146
 O
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 SER A:69 A:69 75.0 0.652 H -59.2 -34.1 18.0 0.157 0.495 B:P36894:0.496
 HOH
 2.554
 OG
 O
SER D:69 D:69 81.0 0.704 H -71.7 -20.9 15.0 0.13 0.574 E:P36894:0.574
 HOH
 3.104
 O
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 SER A:69 A:69 50.0 0.435 H -64.6 -19.5 50.0 0.435 0.0 HOH
 3.323
 N
 O
SER B:69 B:69 75.0 0.652 H -69.6 -24.6 14.0 0.122 0.53 C:P36894:0.53
 HOH
 3.139
 O
 O
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 SER A:69 A:69 55.0 0.478 H -75.1 -8.9 55.0 0.478 0.0 HOH
 7.248
 OG
 O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 SER A:69 A:351 77.0 0.67 T -65.8 -14.4 77.0 0.67 0.0
SER B:69 B:351 89.0 0.774 T -65.3 -13.0 68.0 0.591 0.183 C:Q96B86:0.183
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 SER A:69 A:351 87.0 0.757 H -65.2 -23.9 87.0 0.757 0.0 SO4
 6.711
 N
 O3
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 SER A:69 A:351 63.0 0.548 T -65.7 -11.9 63.0 0.548 0.0 HOH
 9.483
 C
 O
SER B:69 B:351 60.0 0.522 T -65.4 -11.8 47.0 0.409 0.113 C:Q6NW40:0.113
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 SER A:69 A:351 93.0 0.809 H -66.3 -22.3 38.0 0.33 0.479 D:Q6ZVN8:0.478
 HOH
 4.181
 CB
 O
SER B:69 B:351 93.0 0.809 H -66.8 -22.6 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 SER B:69 B:351 51.0 0.443 H -62.0 -25.8 36.0 0.313 0.13 C:Q6NW40:0.13
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 SER A:69 A:69 79.0 0.687 H -63.3 -30.7 15.0 0.13 0.557 B:P36894:0.557
 HOH
 2.543
 OG
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 SER A:69 A:69 52.0 0.452 H -72.8 -20.9 52.0 0.452 0.0 HOH
 7.349
 N
 O
SER B:69 B:69 53.0 0.461 T -67.6 -10.1 53.0 0.461 0.0 HOH
 6.067
 N
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 SER A:63 E:69 56.0 0.487 T -66.2 -14.3 56.0 0.487 0.0
SER B:63 F:69 60.0 0.522 T -68.4 -9.1 60.0 0.522 0.0 HOH
 7.248
 OG
 O
SER C:63 G:69 61.0 0.53 H -60.5 -40.6 NA NA NA
SER D:63 H:69 78.0 0.678 T -63.5 -9.7 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 SER A:58 A:69 56.0 0.487 H -57.4 -32.6 56.0 0.487 0.0 HOH
 7.048
 OG
 O
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 SER A:70 A:69 87.0 0.757 H -63.0 -34.9 87.0 0.757 0.0 HOH
 3.234
 CB
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 LEU A:59 X:69 128.0 0.753 H -68.8 -34.4 128.0 0.753 0.0 HOH
 6.055
 CD2
 O
LEU B:59 Y:69 101.0 0.594 H -57.4 -39.7 101.0 0.594 0.0 HOH
 3.561
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 SER A:351 A:351 63.0 0.548 H -64.0 -25.7