Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 27269898 . T A CCDS13576.1:NM_000484.3:c.2051cAt>cTt_NP_000475.1:p.684H>L Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5buo 1 P05067 100.0 0.0 X-RAY
 2016-07-13 HIS A:316 NA:NA DO NA DO DO DO NA NA NA
HIS B:316 NA:NA DO NA DO DO DO NA NA NA
2lp1 1 P05067 100.0 1e-62 NMR
 2012-06-06 HIS A:14 A:684 157.0 0.805 -96.5 -179.5 157.0 0.805 0.0
7b3j 1 P05067 100.0 1e-30 NMR
 2021-01-13 HIS A:13 A:13 118.0 0.605 H -82.8 -20.4 118.0 0.605 0.0
7b3k 1 P05067 98.18 1e-29 NMR
 2021-01-13 HIS A:13 A:13 117.0 0.6 -157.6 173.1 72.0 0.369 0.231 B:None:0.231
 DAR
DAR
DLE
DHI
2TL
DHI
DAR
DSG
DAR
 8.680
9.933
7.490
6.477
4.433
2.353
1.734
4.759
6.747
 HE2
HE2
HE2
HE2
HE2
HE2
HE2
HE2
HE2
 HH21
O
O
O
O
O
HB3
N
N
2mxu 1 P05067 100.0 1e-22 SOLID-STATE NMR
 2015-05-06 HIS A:13 A:13 169.0 0.867 -121.7 143.3 90.0 0.462 0.405 B:P05067:0.405
HIS B:13 B:13 152.0 0.779 -121.9 133.8 46.0 0.236 0.543 C:P05067:0.282
A:P05067:0.262
HIS C:13 C:13 160.0 0.821 -116.1 133.1 47.0 0.241 0.58 D:P05067:0.344
B:P05067:0.236
HIS D:13 D:13 168.0 0.862 -113.8 127.9 63.0 0.323 0.539 C:P05067:0.174
E:P05067:0.364
HIS E:13 E:13 161.0 0.826 -126.0 127.6 58.0 0.297 0.529 F:P05067:0.328
D:P05067:0.2
HIS F:13 F:13 154.0 0.79 -124.4 127.3 49.0 0.251 0.539 G:P05067:0.318
E:P05067:0.221
HIS G:13 G:13 154.0 0.79 -122.5 128.6 49.0 0.251 0.539 F:P05067:0.21
H:P05067:0.323
HIS H:13 H:13 155.0 0.795 -130.8 129.7 51.0 0.262 0.533 G:P05067:0.226
I:P05067:0.313
HIS I:13 I:13 158.0 0.81 -127.5 129.9 45.0 0.231 0.579 H:P05067:0.282
J:P05067:0.297
HIS J:13 J:13 157.0 0.805 -120.8 135.4 45.0 0.231 0.574 L:P05067:0.005
I:P05067:0.133
K:P05067:0.446
HIS K:13 K:13 150.0 0.769 -123.2 119.0 47.0 0.241 0.528 L:P05067:0.277
I:P05067:0.026
J:P05067:0.251
HIS L:13 L:13 163.0 0.836 -132.3 150.2 142.0 0.728 0.108 K:P05067:0.108
2nao 1 P05067 100.0 1e-22 NMR
 2016-07-27 HIS A:13 A:13 106.0 0.544 -119.0 159.8 95.0 0.487 0.057 B:P05067:0.056
HIS B:13 B:13 181.0 0.928 -161.4 43.8 94.0 0.482 0.446 A:P05067:0.421
C:P05067:0.026
HIS C:13 C:13 155.0 0.795 -162.4 171.5 128.0 0.656 0.139 B:P05067:0.138
HIS D:13 D:13 102.0 0.523 -109.1 -38.7 63.0 0.323 0.2 E:P05067:0.2
HIS E:13 E:13 168.0 0.862 S -170.1 88.7 94.0 0.482 0.38 D:P05067:0.015
F:P05067:0.364
HIS F:13 F:13 143.0 0.733 -177.6 166.7 106.0 0.544 0.189 E:P05067:0.19
2wk3 2 P05067 100.0 1e-22 X-RAY
 2009-11-03 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
HIS D:13 NA:NA DO NA DO DO DO NA NA NA
5kk3 1 P05067 100.0 1e-22 SOLID-STATE NMR
 2016-07-13 HIS A:13 A:13 127.0 0.651 -90.8 134.2 83.0 0.426 0.225 J:P05067:0.169
K:P05067:0.01
B:P05067:0.051
HIS B:13 B:13 152.0 0.779 S -119.5 -72.8 72.0 0.369 0.41 C:P05067:0.133
A:P05067:0.272
HIS C:13 C:13 115.0 0.59 -108.0 155.9 47.0 0.241 0.349 D:P05067:0.103
E:P05067:0.005
B:P05067:0.246
HIS D:13 D:13 141.0 0.723 -118.6 113.3 29.0 0.149 0.574 C:P05067:0.277
M:P05067:0.292
E:P05067:0.021
N:P05067:0.154
B:P05067:0.005
HIS E:13 E:13 124.0 0.636 -140.0 132.7 41.0 0.21 0.426 F:P05067:0.133
C:P05067:0.021
D:P05067:0.287
HIS F:13 F:13 173.0 0.887 S -75.0 71.9 68.0 0.349 0.538 O:P05067:0.087
Q:P05067:0.169
G:P05067:0.221
D:P05067:0.031
E:P05067:0.01
P:P05067:0.231
HIS G:13 G:13 176.0 0.903 -165.1 147.6 54.0 0.277 0.626 F:P05067:0.328
Q:P05067:0.221
H:P05067:0.077
R:P05067:0.164
P:P05067:0.01
HIS H:13 H:13 175.0 0.897 -178.6 -173.4 35.0 0.179 0.718 Q:P05067:0.01
G:P05067:0.344
I:P05067:0.277
R:P05067:0.164
HIS I:13 I:13 161.0 0.826 S -112.4 -51.0 120.0 0.615 0.211 H:P05067:0.21
HIS J:13 J:13 177.0 0.908 S -77.5 60.5 124.0 0.636 0.272 K:P05067:0.272
HIS K:13 K:13 160.0 0.821 -80.7 -174.6 39.0 0.2 0.621 C:P05067:0.256
L:P05067:0.344
D:P05067:0.01
A:P05067:0.036
J:P05067:0.036
B:P05067:0.226
HIS L:13 L:13 147.0 0.754 -137.2 136.7 33.0 0.169 0.585 C:P05067:0.215
M:P05067:0.138
D:P05067:0.282
E:P05067:0.031
N:P05067:0.021
K:P05067:0.164
HIS M:13 M:13 125.0 0.641 -138.9 141.3 38.0 0.195 0.446 L:P05067:0.323
J:P05067:0.026
N:P05067:0.123
K:P05067:0.01
HIS N:13 N:13 122.0 0.626 -75.1 81.0 51.0 0.262 0.364 O:P05067:0.097
M:P05067:0.267
HIS O:13 O:13 116.0 0.595 -173.9 170.9 18.0 0.092 0.503 F:P05067:0.138
L:P05067:0.01
G:P05067:0.082
M:P05067:0.092
E:P05067:0.144
N:P05067:0.164
P:P05067:0.072
HIS P:13 P:13 149.0 0.764 -135.3 148.4 16.0 0.082 0.682 O:P05067:0.149
Q:P05067:0.205
H:P05067:0.313
G:P05067:0.215
I:P05067:0.051
HIS Q:13 Q:13 179.0 0.918 -71.8 -71.8 122.0 0.626 0.292 R:P05067:0.138
P:P05067:0.154
HIS R:13 R:13 164.0 0.841 S -170.8 159.4 124.0 0.636 0.205 Q:P05067:0.169
I:P05067:0.082
5oqv 1 P05067 100.0 1e-22 EM
 2017-09-13 HIS A:13 A:13 99.0 0.508 -118.7 130.6 3.0 0.015 0.493 H:P05067:0.231
C:P05067:0.262
HIS B:13 B:13 101.0 0.518 -118.7 130.6 4.0 0.021 0.497 I:P05067:0.236
D:P05067:0.262
HIS C:13 C:13 99.0 0.508 -118.7 130.6 3.0 0.015 0.493 A:P05067:0.231
E:P05067:0.256
HIS D:13 D:13 100.0 0.513 -118.7 130.6 55.0 0.282 0.231 B:P05067:0.231
HIS E:13 E:13 100.0 0.513 -118.7 130.5 54.0 0.277 0.236 C:P05067:0.236
HIS F:13 F:13 101.0 0.518 -118.7 130.6 50.0 0.256 0.262 H:P05067:0.262
HIS G:13 G:13 99.0 0.508 -118.7 130.5 48.0 0.246 0.262 I:P05067:0.262
HIS H:13 H:13 100.0 0.513 -118.7 130.5 3.0 0.015 0.498 F:P05067:0.236
A:P05067:0.262
HIS I:13 I:13 100.0 0.513 -118.7 130.5 4.0 0.021 0.492 G:P05067:0.231
B:P05067:0.262
6rhy 1 P05067 100.0 1e-22 NMR
 2019-09-25 HIS A:13 A:13 93.0 0.477 E -127.6 135.6 93.0 0.477 0.0
HIS B:13 B:13 96.0 0.492 -75.5 86.7 96.0 0.492 0.0
HIS C:13 C:13 90.0 0.462 E -127.5 136.2 90.0 0.462 0.0
HIS D:13 D:13 95.0 0.487 -75.5 87.0 95.0 0.487 0.0
6szf 1 P05067 100.0 1e-22 NMR
 2020-10-14 HIS A:13 A:13 145.0 0.744 T -46.8 -26.5 145.0 0.744 0.0
6ti6 2 P05067 100.0 1e-22 SOLID-STATE NMR
 2020-07-22 HIS B:13 B:13 166.0 0.851 -85.2 125.5 58.0 0.297 0.554 D:P05067:0.062
A:P05067:0.246
C:P05067:0.308
HIS D:13 D:13 147.0 0.754 -86.8 126.8 50.0 0.256 0.498 C:P05067:0.215
E:P05067:0.282
HIS F:13 F:13 151.0 0.774 -85.8 124.7 43.0 0.221 0.553 G:P05067:0.221
E:P05067:0.333
HIS H:13 H:13 150.0 0.769 -63.5 122.4 94.0 0.482 0.287 G:P05067:0.287
HIS J:13 J:13 162.0 0.831 -83.2 123.3 58.0 0.297 0.534 I:P05067:0.246
L:P05067:0.056
K:P05067:0.287
HIS L:13 L:13 139.0 0.713 -87.6 132.2 37.0 0.19 0.523 M:P05067:0.282
K:P05067:0.236
HIS N:13 N:13 148.0 0.759 -86.7 127.7 42.0 0.215 0.544 O:P05067:0.221
M:P05067:0.328
HIS P:13 P:13 150.0 0.769 -60.8 120.0 96.0 0.492 0.277 O:P05067:0.277
6ti7 2 P05067 100.0 1e-22 SOLID-STATE NMR
 2020-07-22 HIS B:13 B:13 153.0 0.785 -72.9 110.9 53.0 0.272 0.513 C:P05067:0.195
A:P05067:0.313
HIS D:13 D:13 143.0 0.733 -87.4 132.5 52.0 0.267 0.466 C:P05067:0.256
E:P05067:0.21
HIS F:13 F:13 156.0 0.8 -72.9 125.9 48.0 0.246 0.554 G:P05067:0.236
E:P05067:0.318
HIS H:13 H:13 155.0 0.795 -57.3 128.0 98.0 0.503 0.292 G:P05067:0.292
HIS I:13 I:13 145.0 0.744 -80.6 92.2 101.0 0.518 0.226 J:P05067:0.226
HIS K:13 K:13 157.0 0.805 -83.0 92.7 47.0 0.241 0.564 L:P05067:0.236
J:P05067:0.333
HIS M:13 M:13 160.0 0.821 -81.0 102.3 57.0 0.292 0.529 L:P05067:0.287
N:P05067:0.246
HIS O:13 O:13 154.0 0.79 -119.4 114.5 56.0 0.287 0.503 N:P05067:0.272
P:P05067:0.231
7q4b 1 P05067 100.0 1e-22 EM
 2021-11-24 HIS A:13 R:13 97.0 0.497 -149.5 153.4 15.0 0.077 0.42 C:P05067:0.297
E:P05067:0.123
 HOH
 8.175
 C
 O
HIS B:13 A:13 95.0 0.487 -149.4 153.3 17.0 0.087 0.4 F:P05067:0.118
D:P05067:0.287
 HOH
 8.278
 C
 O
HIS C:13 B:13 97.0 0.497 -149.5 153.4 15.0 0.077 0.42 G:P05067:0.297
A:P05067:0.123
 HOH
 8.242
 C
 O
HIS D:13 C:13 95.0 0.487 -149.5 153.4 15.0 0.077 0.41 H:P05067:0.292
B:P05067:0.118
 HOH
 8.253
 C
 O
HIS E:13 D:13 97.0 0.497 -149.5 153.4 39.0 0.2 0.297 A:P05067:0.297
 HOH
 8.243
 C
 O
HIS F:13 E:13 96.0 0.492 -149.4 153.4 39.0 0.2 0.292 B:P05067:0.292
 HOH
 8.169
 C
 O
HIS G:13 F:13 97.0 0.497 -149.5 153.4 15.0 0.077 0.42 I:P05067:0.297
C:P05067:0.123
 HOH
 8.182
 C
 O
HIS H:13 G:13 95.0 0.487 -149.4 153.3 16.0 0.082 0.405 D:P05067:0.113
J:P05067:0.292
 HOH
 8.288
 C
 O
HIS I:13 H:13 96.0 0.492 -149.4 153.3 73.0 0.374 0.118 G:P05067:0.118
 HOH
 8.204
 C
 O
HIS J:13 I:13 97.0 0.497 -149.4 153.4 74.0 0.379 0.118 H:P05067:0.118
 HOH
 8.243
 C
 O
7q4m 1 P05067 100.0 1e-22 EM
 2021-11-24 HIS A:13 A:13 143.0 0.733 -122.0 138.1 45.0 0.231 0.502 C:P05067:0.246
G:P05067:0.256
HIS B:13 B:13 145.0 0.744 -137.9 126.7 46.0 0.236 0.508 H:P05067:0.256
D:P05067:0.251
HIS C:13 C:13 146.0 0.749 -123.5 96.0 53.0 0.272 0.477 A:P05067:0.236
E:P05067:0.246
HIS D:13 D:13 140.0 0.718 -137.9 126.8 45.0 0.231 0.487 F:P05067:0.236
B:P05067:0.251
HIS E:13 E:13 145.0 0.744 -137.0 114.7 95.0 0.487 0.257 C:P05067:0.256
HIS F:13 F:13 142.0 0.728 -134.9 123.9 91.0 0.467 0.261 D:P05067:0.262
HIS G:13 G:13 143.0 0.733 -133.0 130.0 43.0 0.221 0.512 I:P05067:0.282
A:P05067:0.236
HIS H:13 H:13 145.0 0.744 -137.9 126.8 46.0 0.236 0.508 J:P05067:0.251
B:P05067:0.256
HIS I:13 I:13 143.0 0.733 -135.0 125.6 98.0 0.503 0.23 G:P05067:0.231
HIS J:13 J:13 141.0 0.723 -137.8 126.8 95.0 0.487 0.236 H:P05067:0.236
2g47 2 ? 100.0 1e-21 X-RAY
 2006-10-24 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
HIS D:13 NA:NA DO NA DO DO DO NA NA NA
2lfm 1 P05067 100.0 1e-21 NMR
 2011-07-20 HIS A:13 A:13 163.0 0.836 G -74.3 -21.7 163.0 0.836 0.0
2lmn 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2011-12-28 HIS A:13 A:13 163.0 0.836 -106.5 -172.3 152.0 0.779 0.057 B:P05067:0.056
HIS B:13 B:13 156.0 0.8 -132.4 104.9 66.0 0.338 0.462 C:P05067:0.364
A:P05067:0.097
HIS C:13 C:13 163.0 0.836 -130.2 125.5 53.0 0.272 0.564 D:P05067:0.359
E:P05067:0.031
B:P05067:0.164
HIS D:13 D:13 152.0 0.779 -133.0 134.9 40.0 0.205 0.574 C:P05067:0.2
E:P05067:0.374
HIS E:13 E:13 146.0 0.749 -138.9 130.8 49.0 0.251 0.498 F:P05067:0.313
D:P05067:0.185
HIS F:13 F:13 112.0 0.574 -161.1 109.8 84.0 0.431 0.143 E:P05067:0.144
HIS G:13 G:13 123.0 0.631 -104.8 -168.8 109.0 0.559 0.072 H:P05067:0.072
HIS H:13 H:13 160.0 0.821 -127.1 115.7 53.0 0.272 0.549 G:P05067:0.21
I:P05067:0.333
J:P05067:0.01
HIS I:13 I:13 161.0 0.826 -116.2 170.2 71.0 0.364 0.462 H:P05067:0.359
G:P05067:0.092
J:P05067:0.051
HIS J:13 J:13 149.0 0.764 -132.6 147.0 45.0 0.231 0.533 I:P05067:0.19
K:P05067:0.344
HIS K:13 K:13 157.0 0.805 -134.3 127.5 62.0 0.318 0.487 L:P05067:0.313
J:P05067:0.174
HIS L:13 L:13 148.0 0.759 -91.3 -177.5 85.0 0.436 0.323 K:P05067:0.323
2lmo 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2011-12-28 HIS A:13 A:13 144.0 0.738 -106.2 165.9 124.0 0.636 0.102 B:P05067:0.103
HIS B:13 B:13 140.0 0.718 -149.8 163.5 35.0 0.179 0.539 C:P05067:0.128
D:P05067:0.026
A:P05067:0.4
HIS C:13 C:13 175.0 0.897 -152.1 119.3 55.0 0.282 0.615 D:P05067:0.374
B:P05067:0.241
HIS D:13 D:13 190.0 0.974 -78.4 124.6 51.0 0.262 0.712 C:P05067:0.354
E:P05067:0.359
HIS E:13 E:13 151.0 0.774 -121.4 115.0 48.0 0.246 0.528 F:P05067:0.328
D:P05067:0.2
HIS F:13 F:13 141.0 0.723 -153.1 114.0 84.0 0.431 0.292 C:P05067:0.01
D:P05067:0.097
E:P05067:0.19
HIS G:13 G:13 136.0 0.697 -133.4 -177.9 118.0 0.605 0.092 H:P05067:0.092
HIS H:13 H:13 160.0 0.821 -140.1 100.2 54.0 0.277 0.544 G:P05067:0.241
I:P05067:0.318
HIS I:13 I:13 146.0 0.749 -159.4 173.1 25.0 0.128 0.621 H:P05067:0.333
G:P05067:0.031
J:P05067:0.292
K:P05067:0.015
HIS J:13 J:13 200.0 1.0 S -62.0 118.3 58.0 0.297 0.703 I:P05067:0.462
K:P05067:0.267
HIS K:13 K:13 163.0 0.836 -115.9 161.9 43.0 0.221 0.615 L:P05067:0.113
I:P05067:0.01
J:P05067:0.503
HIS L:13 L:13 159.0 0.815 -158.0 107.4 149.0 0.764 0.051 K:P05067:0.051
2lmp 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2011-12-28 HIS A:13 A:13 173.0 0.887 -125.5 133.9 95.0 0.487 0.4 C:P05067:0.215
D:P05067:0.179
B:P05067:0.118
HIS B:13 B:13 198.0 1.0 -71.1 129.1 25.0 0.128 0.872 C:P05067:0.277
D:P05067:0.19
A:P05067:0.431
J:P05067:0.01
E:P05067:0.21
HIS C:13 C:13 144.0 0.738 -117.4 140.6 6.0 0.031 0.707 F:P05067:0.241
D:P05067:0.21
E:P05067:0.241
K:P05067:0.026
B:P05067:0.231
HIS D:13 D:13 154.0 0.79 -161.5 112.9 17.0 0.087 0.703 F:P05067:0.318
C:P05067:0.282
E:P05067:0.313
HIS E:13 E:13 153.0 0.785 -146.7 104.5 73.0 0.374 0.411 F:P05067:0.256
D:P05067:0.226
HIS F:13 F:13 125.0 0.641 -149.7 119.2 90.0 0.462 0.179 E:P05067:0.179
HIS G:13 G:13 185.0 0.949 -92.4 109.6 80.0 0.41 0.539 H:P05067:0.456
I:P05067:0.221
J:P05067:0.062
HIS H:13 H:13 151.0 0.774 -98.2 111.1 11.0 0.056 0.718 G:P05067:0.205
I:P05067:0.462
J:P05067:0.215
P:P05067:0.108
K:P05067:0.062
HIS I:13 I:13 146.0 0.749 -130.8 126.7 14.0 0.072 0.677 H:P05067:0.195
L:P05067:0.041
J:P05067:0.415
K:P05067:0.231
HIS J:13 J:13 173.0 0.887 -139.3 99.8 17.0 0.087 0.8 L:P05067:0.282
I:P05067:0.303
K:P05067:0.421
HIS K:13 K:13 149.0 0.764 -145.5 99.7 26.0 0.133 0.631 Q:P05067:0.005
L:P05067:0.379
I:P05067:0.01
R:P05067:0.036
J:P05067:0.297
HIS L:13 L:13 145.0 0.744 -155.6 126.9 89.0 0.456 0.288 R:P05067:0.159
K:P05067:0.128
HIS M:13 M:13 166.0 0.851 -78.5 99.1 35.0 0.179 0.672 O:P05067:0.221
N:P05067:0.456
P:P05067:0.118
B:P05067:0.174
HIS N:13 N:13 190.0 0.974 S -48.2 119.4 22.0 0.113 0.861 O:P05067:0.277
M:P05067:0.405
P:P05067:0.272
B:P05067:0.179
HIS O:13 O:13 145.0 0.744 -142.2 141.7 8.0 0.041 0.703 Q:P05067:0.246
N:P05067:0.179
P:P05067:0.482
HIS P:13 P:13 154.0 0.79 -117.0 127.3 18.0 0.092 0.698 O:P05067:0.113
Q:P05067:0.569
R:P05067:0.256
HIS Q:13 Q:13 166.0 0.851 -135.4 101.2 42.0 0.215 0.636 R:P05067:0.456
P:P05067:0.272
HIS R:13 R:13 155.0 0.795 -145.4 94.5 111.0 0.569 0.226 F:P05067:0.082
Q:P05067:0.144
2lmq 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2011-12-28 HIS A:13 A:13 141.0 0.723 -98.9 162.1 137.0 0.703 0.02 B:P05067:0.021
HIS B:13 B:13 167.0 0.856 -143.0 94.1 61.0 0.313 0.543 C:P05067:0.354
D:P05067:0.026
A:P05067:0.21
HIS C:13 C:13 172.0 0.882 -139.9 139.8 42.0 0.215 0.667 D:P05067:0.262
A:P05067:0.318
B:P05067:0.2
HIS D:13 D:13 147.0 0.754 -143.9 122.7 8.0 0.041 0.713 C:P05067:0.436
A:P05067:0.205
E:P05067:0.123
B:P05067:0.195
HIS E:13 E:13 166.0 0.851 -64.3 140.9 9.0 0.046 0.805 F:P05067:0.179
C:P05067:0.267
D:P05067:0.492
J:P05067:0.062
B:P05067:0.067
HIS F:13 F:13 131.0 0.672 -146.1 117.3 41.0 0.21 0.462 C:P05067:0.015
D:P05067:0.226
E:P05067:0.323
HIS G:13 G:13 177.0 0.908 -145.4 131.6 129.0 0.662 0.246 H:P05067:0.246
HIS H:13 H:13 151.0 0.774 -147.6 115.0 51.0 0.262 0.512 G:P05067:0.318
I:P05067:0.195
HIS I:13 I:13 161.0 0.826 -147.8 120.2 33.0 0.169 0.657 H:P05067:0.338
G:P05067:0.277
J:P05067:0.108
HIS J:13 J:13 157.0 0.805 -124.9 127.3 2.0 0.01 0.795 H:P05067:0.303
G:P05067:0.133
I:P05067:0.277
K:P05067:0.308
HIS K:13 K:13 171.0 0.877 -110.2 157.6 12.0 0.062 0.815 H:P05067:0.179
L:P05067:0.174
I:P05067:0.246
J:P05067:0.328
P:P05067:0.174
HIS L:13 L:13 167.0 0.856 -146.9 98.0 74.0 0.379 0.477 I:P05067:0.128
J:P05067:0.226
P:P05067:0.144
K:P05067:0.221
HIS M:13 M:13 160.0 0.821 -119.3 130.4 124.0 0.636 0.185 N:P05067:0.185
HIS N:13 N:13 143.0 0.733 -79.7 161.3 59.0 0.303 0.43 O:P05067:0.026
M:P05067:0.415
HIS O:13 O:13 149.0 0.764 -131.3 138.3 29.0 0.149 0.615 M:P05067:0.318
N:P05067:0.231
P:P05067:0.231
HIS P:13 P:13 158.0 0.81 -120.6 110.8 3.0 0.015 0.795 O:P05067:0.379
Q:P05067:0.21
C:P05067:0.087
M:P05067:0.215
D:P05067:0.021
N:P05067:0.205
B:P05067:0.005
HIS Q:13 Q:13 194.0 0.995 -67.4 105.3 17.0 0.087 0.908 O:P05067:0.262
C:P05067:0.082
R:P05067:0.138
D:P05067:0.174
N:P05067:0.21
P:P05067:0.441
HIS R:13 R:13 169.0 0.867 -89.0 119.6 47.0 0.241 0.626 O:P05067:0.133
Q:P05067:0.287
D:P05067:0.262
P:P05067:0.2
2m4j 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2013-09-25 HIS A:13 A:13 119.0 0.61 -135.3 147.4 61.0 0.313 0.297 D:P05067:0.297
HIS B:13 B:13 117.0 0.6 -135.7 147.4 59.0 0.303 0.297 E:P05067:0.297
HIS C:13 C:13 117.0 0.6 -135.4 147.7 60.0 0.308 0.292 F:P05067:0.292
HIS D:13 D:13 118.0 0.605 -130.0 150.7 15.0 0.077 0.528 G:P05067:0.297
A:P05067:0.231
HIS E:13 E:13 117.0 0.6 -135.7 146.4 15.0 0.077 0.523 H:P05067:0.297
B:P05067:0.226
HIS F:13 F:13 116.0 0.595 -135.5 145.9 15.0 0.077 0.518 C:P05067:0.226
I:P05067:0.292
HIS G:13 G:13 119.0 0.61 -135.2 147.1 74.0 0.379 0.231 D:P05067:0.231
HIS H:13 H:13 115.0 0.59 -135.3 147.0 71.0 0.364 0.226 E:P05067:0.226
HIS I:13 I:13 115.0 0.59 -135.2 146.8 71.0 0.364 0.226 F:P05067:0.226
2m9r 1 P05067 100.0 1e-21 NMR
 2013-09-11 HIS A:13 A:13 178.0 0.913 S -87.0 -62.5 178.0 0.913 0.0 23Y
 7.124
 HA
 HCB2
2m9s 1 P05067 100.0 1e-21 NMR
 2013-09-11 HIS A:13 A:13 175.0 0.897 S -122.7 -77.6 175.0 0.897 0.0 23Y
 2.336
 HB2
 HCG4
2otk 1 P05067 100.0 1e-21 NMR
 2008-02-12 HIS A:13 NA:NA DO NA DO DO DO NA NA NA
3ifn 3 P05067 100.0 1e-21 X-RAY
 2009-11-17 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
4m1c 4 P05067 100.0 1e-21 X-RAY
 2014-08-06 HIS G:13 NA:NA DO NA DO DO DO NA NA NA
HIS H:13 NA:NA DO NA DO DO DO NA NA NA
4mvi 2 P05067 100.0 1e-21 X-RAY
 2015-08-12 HIS B:13 NA:NA DO NA DO DO DO NA NA NA
4mvl 2 P05067 100.0 1e-21 X-RAY
 2015-08-12 HIS E:13 NA:NA DO NA DO DO DO NA NA NA
HIS F:13 NA:NA DO NA DO DO DO NA NA NA
HIS G:13 NA:NA DO NA DO DO DO NA NA NA
HIS H:13 NA:NA DO NA DO DO DO NA NA NA
4nge 2 P05067 100.0 1e-21 X-RAY
 2014-05-14 HIS B:13 NA:NA DO NA DO DO DO NA NA NA
HIS E:13 NA:NA DO NA DO DO DO NA NA NA
4ong 3 P05067 100.0 1e-21 X-RAY
 2014-06-11 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
6oc9 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2019-06-05 HIS A:13 A:13 138.0 0.708 -166.3 -174.5 98.0 0.503 0.205 B:P05067:0.205
HIS B:13 B:13 152.0 0.779 165.2 145.1 21.0 0.108 0.671 A:P05067:0.436
E:P05067:0.082
C:P05067:0.277
HIS C:13 C:13 174.0 0.892 -128.8 114.6 43.0 0.221 0.671 A:P05067:0.113
D:P05067:0.062
B:P05067:0.41
E:P05067:0.251
HIS D:13 D:13 162.0 0.831 137.8 172.8 42.0 0.215 0.616 C:P05067:0.092
E:P05067:0.579
HIS E:13 E:13 168.0 0.862 93.9 113.4 126.0 0.646 0.216 D:P05067:0.215
HIS F:13 F:13 126.0 0.646 -178.3 155.1 83.0 0.426 0.22 H:P05067:0.056
G:P05067:0.215
HIS G:13 G:13 157.0 0.805 -134.1 -54.9 87.0 0.446 0.359 F:P05067:0.251
H:P05067:0.113
HIS H:13 H:13 156.0 0.8 -167.1 132.4 14.0 0.072 0.728 F:P05067:0.015
G:P05067:0.323
I:P05067:0.421
J:P05067:0.051
HIS I:13 I:13 173.0 0.887 -153.7 172.6 47.0 0.241 0.646 H:P05067:0.349
J:P05067:0.303
HIS J:13 J:13 180.0 0.923 -149.0 43.0 111.0 0.569 0.354 H:P05067:0.067
I:P05067:0.313
6shs 1 P05067 100.0 1e-21 EM
 2019-11-06 HIS A:13 A:13 99.0 0.508 -145.9 177.5 4.0 0.021 0.487 C:P05067:0.277
G:P05067:0.205
HIS B:13 B:13 97.0 0.497 -145.9 177.5 3.0 0.015 0.482 H:P05067:0.21
D:P05067:0.277
HIS C:13 C:13 99.0 0.508 -145.9 177.5 4.0 0.021 0.487 A:P05067:0.21
E:P05067:0.282
HIS D:13 H:13 96.0 0.492 -145.9 177.5 3.0 0.015 0.477 F:P05067:0.272
B:P05067:0.2
HIS E:13 D:13 102.0 0.523 -145.9 177.5 60.0 0.308 0.215 C:P05067:0.215
HIS F:13 I:13 98.0 0.503 -145.9 177.5 58.0 0.297 0.206 D:P05067:0.205
HIS G:13 E:13 99.0 0.508 -145.9 177.5 4.0 0.021 0.487 I:P05067:0.21
A:P05067:0.277
HIS H:13 J:13 98.0 0.503 -145.9 177.5 3.0 0.015 0.488 J:P05067:0.215
B:P05067:0.272
HIS I:13 F:13 99.0 0.508 -145.9 177.5 4.0 0.021 0.487 G:P05067:0.277
K:P05067:0.21
HIS J:13 K:13 98.0 0.503 -145.9 177.5 3.0 0.015 0.488 H:P05067:0.277
L:P05067:0.205
HIS K:13 G:13 96.0 0.492 -145.9 177.5 44.0 0.226 0.266 I:P05067:0.267
HIS L:13 L:13 100.0 0.513 -145.9 177.5 46.0 0.236 0.277 J:P05067:0.277
6ti5 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2020-07-22 HIS A:13 A:13 132.0 0.677 -104.4 116.3 86.0 0.441 0.236 C:P05067:0.01
B:P05067:0.236
HIS B:13 B:13 135.0 0.692 -118.5 115.9 29.0 0.149 0.543 C:P05067:0.251
D:P05067:0.062
A:P05067:0.292
HIS C:13 C:13 143.0 0.733 -115.3 122.4 27.0 0.138 0.595 D:P05067:0.282
E:P05067:0.062
B:P05067:0.308
HIS D:13 D:13 153.0 0.785 -116.9 122.3 33.0 0.169 0.616 F:P05067:0.051
C:P05067:0.308
E:P05067:0.313
HIS E:13 E:13 159.0 0.815 -102.6 121.4 36.0 0.185 0.63 F:P05067:0.303
G:P05067:0.077
D:P05067:0.328
HIS F:13 F:13 129.0 0.662 -113.9 124.0 16.0 0.082 0.58 H:P05067:0.056
G:P05067:0.251
E:P05067:0.333
HIS G:13 G:13 132.0 0.677 -114.2 121.7 21.0 0.108 0.569 F:P05067:0.303
H:P05067:0.267
HIS H:13 H:13 127.0 0.651 -127.0 127.3 72.0 0.369 0.282 G:P05067:0.282
HIS I:13 I:13 123.0 0.631 -110.0 110.4 81.0 0.415 0.216 J:P05067:0.215
K:P05067:0.01
HIS J:13 J:13 135.0 0.692 -113.5 119.8 26.0 0.133 0.559 L:P05067:0.046
I:P05067:0.303
K:P05067:0.256
HIS K:13 K:13 138.0 0.708 -120.2 118.9 27.0 0.138 0.57 L:P05067:0.282
M:P05067:0.051
J:P05067:0.287
HIS L:13 L:13 139.0 0.713 -117.4 121.7 26.0 0.133 0.58 M:P05067:0.313
N:P05067:0.056
K:P05067:0.262
HIS M:13 M:13 151.0 0.774 -102.2 121.8 32.0 0.164 0.61 O:P05067:0.072
L:P05067:0.292
N:P05067:0.318
HIS N:13 N:13 120.0 0.615 -114.3 120.3 10.0 0.051 0.564 O:P05067:0.236
M:P05067:0.328
P:P05067:0.031
HIS O:13 O:13 120.0 0.615 -113.9 123.1 14.0 0.072 0.543 N:P05067:0.277
P:P05067:0.267
HIS P:13 P:13 124.0 0.636 -119.5 124.7 74.0 0.379 0.257 O:P05067:0.256
6ti6 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2020-07-22 HIS A:13 A:13 149.0 0.764 -66.9 117.6 105.0 0.538 0.226 B:P05067:0.226
HIS C:13 C:13 174.0 0.892 -74.3 87.0 50.0 0.256 0.636 D:P05067:0.308
B:P05067:0.328
HIS E:13 E:13 164.0 0.841 -97.9 91.6 61.0 0.313 0.528 D:P05067:0.308
F:P05067:0.221
HIS G:13 G:13 152.0 0.779 -96.9 93.3 50.0 0.256 0.523 F:P05067:0.303
H:P05067:0.215
HIS I:13 I:13 145.0 0.744 -64.3 112.9 101.0 0.518 0.226 J:P05067:0.226
HIS K:13 K:13 171.0 0.877 -84.2 91.5 50.0 0.256 0.621 L:P05067:0.297
J:P05067:0.323
HIS M:13 M:13 167.0 0.856 -103.8 92.9 68.0 0.349 0.507 L:P05067:0.287
N:P05067:0.221
HIS O:13 O:13 160.0 0.821 -97.4 95.7 55.0 0.282 0.539 N:P05067:0.313
P:P05067:0.221
6ti7 1 P05067 100.0 1e-21 SOLID-STATE NMR
 2020-07-22 HIS A:13 A:13 140.0 0.718 -85.9 96.8 94.0 0.482 0.236 B:P05067:0.236
HIS C:13 C:13 149.0 0.764 -86.2 89.6 47.0 0.241 0.523 B:P05067:0.308
D:P05067:0.221
HIS E:13 E:13 152.0 0.779 -90.9 92.8 58.0 0.297 0.482 D:P05067:0.303
F:P05067:0.179
HIS G:13 G:13 158.0 0.81 -96.4 105.0 51.0 0.262 0.548 H:P05067:0.19
F:P05067:0.364
HIS J:13 J:13 152.0 0.779 -69.6 113.7 48.0 0.246 0.533 K:P05067:0.226
I:P05067:0.308
HIS L:13 L:13 138.0 0.708 -97.4 140.8 40.0 0.205 0.503 K:P05067:0.277
M:P05067:0.226
HIS N:13 N:13 148.0 0.759 -64.9 128.3 44.0 0.226 0.533 M:P05067:0.272
O:P05067:0.256
HIS P:13 P:13 163.0 0.836 -95.6 125.5 101.0 0.518 0.318 O:P05067:0.318
6w0o 1 P05067 100.0 1e-21 EM
SOLID-STATE NMR
 2021-01-13 HIS A:13 1:13 142.0 0.728 -160.1 173.0 102.0 0.523 0.205 B:P05067:0.205
HIS B:13 2:13 141.0 0.723 -159.7 173.1 46.0 0.236 0.487 A:P05067:0.282
C:P05067:0.2
HIS C:13 3:13 142.0 0.728 -159.7 173.1 85.0 0.436 0.292 B:P05067:0.292
HIS D:13 4:13 146.0 0.749 -138.2 119.8 112.0 0.574 0.175 E:P05067:0.174
HIS E:13 5:13 146.0 0.749 -138.1 119.6 41.0 0.21 0.539 D:P05067:0.364
F:P05067:0.174
HIS F:13 6:13 144.0 0.738 -138.6 119.8 75.0 0.385 0.353 E:P05067:0.354
6xov 2 P05067 100.0 1e-21 EM
 2021-07-07 HIS B:13 NA:NA DO NA DO DO DO NA NA NA
2lnq 1 P05067 97.5 6e-21 SOLID-STATE NMR
 2012-02-08 HIS A:13 NA:NA DO NA DO DO DO NA NA NA
HIS B:13 NA:NA DO NA DO DO DO NA NA NA
HIS C:13 NA:NA DO NA DO DO DO NA NA NA
HIS D:13 NA:NA DO NA DO DO DO NA NA NA
HIS E:13 NA:NA DO NA DO DO DO NA NA NA
HIS F:13 NA:NA DO NA DO DO DO NA NA NA
HIS G:13 NA:NA DO NA DO DO DO NA NA NA
HIS H:13 NA:NA DO NA DO DO DO NA NA NA
7o1q 1 P09616,P05067 97.73 1e-20 EM
 2021-04-14 HIS A:118 A:118 133.0 0.682 E -121.4 135.6 98.0 0.503 0.179 B:P09616+P05067:0.179
HIS B:118 B:118 133.0 0.682 E -121.5 135.6 97.0 0.497 0.185 C:P09616+P05067:0.185
HIS C:118 C:118 130.0 0.667 E -121.4 135.6 95.0 0.487 0.18 D:P09616+P05067:0.179
HIS D:118 D:118 134.0 0.687 E -121.5 135.7 100.0 0.513 0.174 E:P09616+P05067:0.174
HIS E:118 E:118 132.0 0.677 E -121.4 135.7 98.0 0.503 0.174 F:P09616+P05067:0.174
HIS F:118 F:118 133.0 0.682 E -121.4 135.6 99.0 0.508 0.174 G:P09616+P05067:0.174
HIS G:118 G:118 131.0 0.672 E -121.4 135.6 97.0 0.497 0.175 A:P09616+P05067:0.174
2mvx 1 P05067 97.5 3e-19 SOLID-STATE NMR
 2014-11-26 HIS A:13 A:13 143.0 0.733 -115.1 114.5 30.0 0.154 0.579 F:P05067:0.323
G:P05067:0.195
B:P05067:0.241
HIS B:13 B:13 144.0 0.738 -115.6 115.7 0.0 0.0 0.738 F:P05067:0.036
H:P05067:0.19
C:P05067:0.241
G:P05067:0.323
A:P05067:0.231
HIS C:13 C:13 145.0 0.744 -115.9 114.8 0.0 0.0 0.744 H:P05067:0.328
G:P05067:0.041
I:P05067:0.19
D:P05067:0.246
B:P05067:0.231
HIS D:13 D:13 143.0 0.733 -116.0 114.9 0.0 0.0 0.733 H:P05067:0.041
C:P05067:0.226
I:P05067:0.318
J:P05067:0.174
E:P05067:0.241
HIS E:13 E:13 141.0 0.723 -116.2 114.1 48.0 0.246 0.477 I:P05067:0.041
D:P05067:0.221
J:P05067:0.318
HIS F:13 F:13 139.0 0.713 -115.4 117.5 30.0 0.154 0.559 G:P05067:0.231
A:P05067:0.318
B:P05067:0.185
HIS G:13 G:13 141.0 0.723 -115.9 117.8 0.0 0.0 0.723 F:P05067:0.221
H:P05067:0.236
C:P05067:0.179
A:P05067:0.046
B:P05067:0.323
HIS H:13 H:13 140.0 0.718 -116.1 116.7 0.0 0.0 0.718 C:P05067:0.318
G:P05067:0.215
I:P05067:0.241
D:P05067:0.174
B:P05067:0.041
HIS I:13 I:13 140.0 0.718 -116.1 117.3 0.0 0.0 0.718 H:P05067:0.221
C:P05067:0.041
D:P05067:0.318
J:P05067:0.236
E:P05067:0.164
HIS J:13 J:13 141.0 0.723 -116.0 116.9 49.0 0.251 0.472 I:P05067:0.215
D:P05067:0.041
E:P05067:0.313
3bae 3 ? 100.0 7e-12 X-RAY
 2008-04-15 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
4hix 3 P05067 100.0 7e-12 X-RAY
 2013-03-13 HIS C:13 NA:NA DO NA DO DO DO NA NA NA
1ze7 1 P05067 100.0 1.0 NMR
 2005-05-03 HIS A:14 A:13 154.0 0.79 T -68.9 -39.5 154.0 0.79 0.0
1ze9 1 P05067 100.0 1.0 NMR
 2005-05-03 HIS A:14 A:13 126.0 0.646 G -65.7 -13.2 126.0 0.646 0.0 ZN
 2.147
 NE2
 ZN
2mgt 1 P05067 93.75 1.0 NMR
 2014-11-12 HIS A:14 A:13 158.0 0.81 G -61.1 -19.0 148.0 0.759 0.051 B:P05067:0.051
 ZN
 3.839
 HD2
 ZN
HIS B:14 B:13 148.0 0.759 T -63.3 -20.1 148.0 0.759 0.0 ZN
 5.076
 HD2
 ZN
4xxd 3 P05067 100.0 1.0 X-RAY
 2015-04-29 HIS C:2 NA:NA DO NA DO DO DO NA NA NA
HIS F:2 NA:NA DO NA DO DO DO NA NA NA
5vzy 3 P05067 100.0 1.0 X-RAY
 2017-08-09 HIS C:3 A:13 228.0 1.0 360.0 -32.4 152.0 0.779 0.221 B:Q0KKI6:0.097
A:P0DOX5:0.292
 HOH
 2.348
 N
 O
5w3p 3 P05067 100.0 1.0 X-RAY
 2017-09-20 HIS C:14 P:13 181.0 0.928 -82.5 98.5 181.0 0.928 0.0 SO4
SO4
SO4
HOH
 6.009
4.774
9.477
2.670
 N
O
N
ND1
 O1
O1
O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05067-f1 1 P05067 100.0 0.0 HIS A:684 A:684 146.0 0.749 -58.4 99.6