Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42598262 . A C CCDS13668.1:NM_012105.4:c.382Acg>Ccg_NP_036237.2:p.128T>P Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 THR A:128 A:66 52.0 0.371 -155.9 167.7 52.0 0.371 0.0 HOH
 4.455
 N
 O
THR B:128 B:66 51.0 0.364 -150.8 170.2 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 THR A:128 A:66 60.0 0.429 -132.1 143.4 60.0 0.429 0.0
THR B:128 B:66 64.0 0.457 -132.9 150.6 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 61.0 0.436 -151.3 165.3 61.0 0.436 0.0 HOH
 2.925
 OG1
 O
THR B:54 B:66 57.0 0.407 -156.0 157.0 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 55.0 0.393 -138.3 152.4 NA NA NA
THR B:54 B:66 58.0 0.414 -135.8 161.0 58.0 0.414 0.0 HOH
 3.553
 OG1
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 46.0 0.329 -150.7 154.0 46.0 0.329 0.0 HOH
 2.971
 OG1
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 48.0 0.343 -127.8 162.7 48.0 0.343 0.0 HOH
 5.244
 OG1
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 70.0 0.5 -143.7 169.9 70.0 0.5 0.0 HOH
 3.365
 CB
 O
THR B:54 B:66 53.0 0.379 -139.5 160.1 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 THR A:54 A:66 53.0 0.379 -145.7 151.8 53.0 0.379 0.0 HOH
 5.385
 N
 O
THR B:54 B:66 56.0 0.4 -149.3 157.4 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 THR A:54 A:66 43.0 NA -138.0 168.8 43.0 NA NA HOH
 4.718
 CB
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 THR A:54 A:66 59.0 0.421 -125.3 165.1 59.0 0.421 0.0 HOH
 3.434
 CA
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 THR A:54 A:66 44.0 0.314 -122.1 157.4 44.0 0.314 0.0 HOH
 4.965
 OG1
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 THR A:54 A:66 49.0 0.35 -142.9 164.6 49.0 0.35 0.0 HOH
 2.354
 HG1
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 THR A:54 A:66 52.0 0.371 -151.4 156.0 52.0 0.371 0.0 HOH
 3.460
 OG1
 O
THR B:54 B:66 52.0 0.371 -158.8 164.2 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 THR A:54 A:66 49.0 0.35 -149.5 157.3 49.0 0.35 0.0 HOH
 3.742
 N
 O
THR B:54 B:66 56.0 0.4 -130.2 146.0 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 THR A:54 A:66 66.0 0.471 -146.4 151.2 66.0 0.471 0.0 HOH
 3.853
 N
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 THR A:54 A:66 50.0 0.357 -133.9 156.6 50.0 0.357 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 THR A:54 A:66 66.0 0.471 -150.7 172.0 66.0 0.471 0.0 HOH
 4.785
 N
 O
THR B:54 B:66 59.0 0.421 -153.3 160.4 59.0 0.421 0.0 HOH
 4.796
 N
 O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 THR A:51 A:66 53.0 0.379 -167.6 162.6 53.0 0.379 0.0 HOH
 9.897
 O
 O
THR B:51 B:66 52.0 0.371 -167.7 162.5 NA NA NA
THR C:51 C:66 53.0 0.379 -167.7 162.5 NA NA NA
THR D:51 D:66 53.0 0.379 -167.6 162.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 THR A:128 A:128 59.0 0.421 -143.9 155.6