Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42609510 . G A CCDS13668.1:NM_012105.4:c.472Gtt>Att_NP_036237.2:p.158V>I Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 VAL A:158 A:96 2.0 0.013 E -99.3 134.4 2.0 0.013 0.0 HOH
 2.763
 O
 O
VAL B:158 B:96 1.0 0.006 E -96.4 130.5 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 VAL A:158 A:96 0.0 0.0 E -94.3 96.3 0.0 0.0 0.0
VAL B:158 B:96 4.0 0.026 E -106.2 128.3 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 1.0 0.006 E -113.0 125.9 1.0 0.006 0.0 SO4
HOH
 8.237
2.752
 CG1
O
 O3
O
VAL B:84 B:96 1.0 0.006 E -105.7 132.1 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 1.0 0.006 E -108.0 133.9 NA NA NA
VAL B:84 B:96 0.0 0.0 E -109.2 134.7 0.0 0.0 0.0 SO4
HOH
 8.630
2.546
 CG1
O
 O4
O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 0.0 0.0 E -99.6 130.0 0.0 0.0 0.0 CL
HOH
 7.593
2.764
 CG1
O
 CL
O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 0.0 0.0 E -97.3 122.9 0.0 0.0 0.0 HOH
 2.785
 O
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 0.0 0.0 E -99.9 130.6 0.0 0.0 0.0 CL
HOH
 7.758
3.801
 CG1
C
 CL
O
VAL B:84 B:96 0.0 0.0 E -95.2 135.3 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 1.0 0.006 E -109.4 127.7 1.0 0.006 0.0 HOH
 3.615
 C
 O
VAL B:84 B:96 1.0 0.006 E -99.2 127.4 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 VAL A:84 A:96 1.0 0.006 E -101.4 129.4 1.0 0.006 0.0 CL
HOH
 7.595
2.965
 CG1
O
 CL
O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 VAL A:84 A:96 1.0 0.006 E -104.4 132.3 1.0 0.006 0.0 CL
HOH
 7.706
2.797
 CG1
O
 CL
O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 VAL A:84 A:96 0.0 0.0 E -110.6 140.3 0.0 0.0 0.0 HOH
 3.551
 C
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 VAL A:84 A:96 1.0 0.006 E -105.2 129.3 1.0 0.006 0.0 HOH
 2.793
 O
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 0.0 0.0 E -104.9 126.4 0.0 0.0 0.0 HOH
 2.873
 O
 O
VAL B:84 B:96 1.0 0.006 E -95.7 128.1 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 0.0 0.0 E -96.6 131.8 0.0 0.0 0.0 HOH
 2.916
 O
 O
VAL B:84 B:96 1.0 0.006 E -90.0 121.4 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 2.0 0.013 E -92.6 126.4 2.0 0.013 0.0 HOH
 3.680
 C
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:84 A:96 2.0 0.013 E -90.2 126.6 2.0 0.013 0.0 HOH
 4.905
 O
 O
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 VAL A:84 A:96 0.0 0.0 E -106.3 127.7 0.0 0.0 0.0 HOH
 3.852
 C
 O
VAL B:84 B:96 2.0 0.013 E -99.0 128.4 2.0 0.013 0.0 HOH
 3.815
 C
 O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 VAL A:81 A:96 1.0 0.006 E -89.6 133.9 1.0 0.006 0.0 HOH
 5.987
 CG2
 O
VAL B:81 B:96 1.0 0.006 E -89.6 133.9 NA NA NA
VAL C:81 C:96 0.0 0.0 E -89.6 133.9 NA NA NA
VAL D:81 D:96 1.0 0.006 E -89.6 133.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 VAL A:158 A:158 1.0 0.006 E -90.8 131.6